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Orthopedics General

Mechanism of miRNA-based Aconitum leucostomum Worosch. Monomer inhibition of bone marrow-derived dendritic cell maturation.

Sep 03, 2020

Delvestidine (DLTD) is a monomeric compound isolated from Aconitum leucostomum Worosch, a widely used medicine for local treatment of rheumatoid arthritis (RA). Studies have shown that Aconitum leucos...

Mini-open lateral retropleural/retroperitoneal approaches for thoracic and thoracolumbar junction anterior column pathologies.

Sep 03, 2020

Advancements in less invasive lateral retropleural/retroperitoneal approaches aim to address the limitation of posterolateral approaches and avoid complications associated with anterior open thoracoto...

Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents.

Aug 31, 2020

Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) as major cause of chronic low back pain represent the most common degenerative joint pathologies and are leading causes of pain and disa...

Cartilage and Subchondral Bone Distributions of the Distal Radius: A 3-Dimensional Analysis Using Cadavers.

Aug 31, 2020

To quantify the spatial distributions of cartilage and subchondral bone thickness of the distal radius.Using 17 cadaveric wrists, three types of 3-dimensional models were created: a cartilage-bone mod...

Stretchable, tough and elastic nanofibrous hydrogels with dermis-mimicking network structure.

Aug 31, 2020

Nanofiber-structured hydrogels with robust mechanical properties are promising candidates for the development of multifunctional materials in advanced fields. However, creating such materials that com...

Bio-inspired surface modification of PEEK through the dual cross-linked hydrogel layers.

Aug 31, 2020

The biocompatible high-performance material PEEK (polyetheretherketone) is an attractive implant material, however, its hydrophobicity and high friction coefficients severely hinder its biomedical app...

Combined exposure to formaldehyde and PM: Hematopoietic toxicity and molecular mechanism in mice.

Aug 31, 2020

PM and formaldehyde (FA) are major outdoor and indoor air pollutants in China, respectively, and both are known to be harmful to human health and to be carcinogenic. Of all the known chronic health ef...

Medical prevention and treatment of radiation-induced carotid injury.

Aug 31, 2020

Radiotherapy has significantly improved the survival of cancer patients but is also associated with several adversities, including radiation-induced carotid injury (RICI). The RICI mechanisms are comp...

Prevalence, Characteristics and Clinical Course of Neuropathic Pain in Primary Care Patients Consulting with Low Back-related Leg Pain.

Aug 27, 2020

Little is known about the epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. We aimed to describe prevalence, characteristics and clinical course of l...

Placebo Response Reduction and Accurate Pain Reporting Training Reduces Placebo Responses in a Clinical Trial on Chronic Low Back Pain: Results from a Comparison to the Literature.

Aug 27, 2020

A literature review was conducted to compare placebo responses in a recent trial-which implemented an Accurate Pain Reporting (APR) and Placebo Response Reduction (PRR) training program-to placebo res...

[Classification and surgical strategy of Work Ⅰ congenital first branchial cleft anomaly based on adjacent anatomy].

Aug 27, 2020

To explore the adjacent anatomic relationship and classification of Work Ⅰ congenital first branchial cleft anomaly(CFBCA) in order to guide clinical practice. The data of 48 cases of Work Ⅰ C...

[Clinical characteristics and etiology of temporomandibular joint herniation into external ear canal].

Aug 27, 2020

To summarize the cases of temporomandibular joint herniation into external auditory canal found and treated in our hospital, to improve the understanding of oral and maxillofacial diseases and otologi...

[Clinical research on the surgical treatment of complex maxillary sinus diseases by pyriform aperture extend prelacimal recess approach].

Aug 27, 2020

The aim of this study is to explore the operative method, indication and clinical effect of enlarging anterior lacrimal Fossa via Piriform foramen for complex lesions of maxillary Sinus. By imaging an...

Closed Metacarpal Neck Fractures: A Review of Resource Use in Operative and Nonoperative Management.

Aug 27, 2020

Closed metacarpal neck fractures are extremely common. The authors investigated resource use among those managed operatively versus nonoperatively. They hypothesized that considerable use of services ...

Intramedullary Humeral Nail Placement through the Rotator Interval: An Anatomic and Radiographic Analysis.

Aug 24, 2020

Antegrade intramedullary humeral nails (IMNs) are an effective fixation method for certain proximal humerus and humeral shaft fractures. However, due to potential rotator cuff damage during nail inser...

Back Pain in Surgically Treated Degenerative Lumbar Spondylolisthesis: What can we tell our patients?

Aug 24, 2020

Surgery for degenerative lumbar spondylolisthesis (DLS) has traditionally been indicated for patients with neurogenic claudication. Surgery improves patients' disability and lower extremity symptoms, ...

Anterior cruciate ligament agonist and antagonist muscle force differences between males and females during perturbed walking.

Aug 24, 2020

Anterior cruciate ligament (ACL) injuries most commonly occur following a perturbation. Perturbations make the athlete unbalanced or at loss of control, which ultimately can lead to injury. The purpos...

Regional Variation in Bone Turnover at the Iliac Crest versus the Greater Trochanter.

Aug 24, 2020

Iliac crest bone biopsy with histomorphometry is the gold standard for diagnosis of abnormalities in bone turnover, yet fractures more frequently occur at the greater trochanter of the hip. Whether bo...

Effects of loading direction in prolonged clenching on stress distribution in the temporomandibular joint.

Aug 24, 2020

Parafunctional habits, such as bruxism and prolonged clenching, have been associated with dysfunctional hyperactivity of the masticatory muscles, including the lateral pterygoid muscle. The resultant ...

miR300 intervenes Smad3/β-catenin/RunX2 crosstalk for therapy with an alternate function as indicative biomarker in osteoporosis.

Aug 24, 2020

The study reports a theranostic nature of rno-miR-300 (miR300) in the osteoblast functioning, by influencing the signaling pathway(s), associated with osteoblast differentiation. Excessive expression ...

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