Aug 06, 2020

Neurotrophin receptor-interacting MAGE homologue (NRAGE) plays a crucial role in the regulation of bone metabolism. The present study investigated the regulation role of NRAGE on autophagy activation ...

Aug 06, 2020

Hyperostosis in meningiomas can be present in 4.5% to 44% of cases. Radical resection should include aggressive removal of invaded bone. It is not clear however to what extent bone removal should be c...

Aug 06, 2020

Distant metastases occur when non-small cell lung cancer (NSCLC) is at late stages. Bone metastasis is one of the most frequent metastases of NSCLC and leads to poor prognosis. It has been reported th...

Aug 03, 2020

Osteoporosis is a metabolic bone disease that increases the risk for fragility fractures. Screening and diagnosis can be achieved by measuring bone mineral density (BMD) using quantitative CT tomograp...

Aug 03, 2020

Patients undergoing long-segment fusions from the lower thoracic (LT) spine to the sacrum for adult spinal deformity (ASD) correction are at risk for proximal junctional kyphosis (PJK). One mechanism ...

Aug 03, 2020

The purpose of this investigation was to characterize the bone health in preoperative spine surgery patients. This information will provide a framework to understand the needs and methods for providin...

Aug 03, 2020

Patients with osteopenia or osteoporosis who require surgery for symptomatic degenerative spondylolisthesis may have higher rates of postoperative pseudarthrosis and need for revision surgery than pat...

Aug 03, 2020

Postoperative subsidence of transforaminal lumbar interbody fusion (TLIF) cages can result in loss of lordosis and foraminal height, and potential recurrence of nerve root impingement. The objectives ...

Jul 30, 2020

Low back pain is a common condition and one of the leading reasons for years of chronic disability. Rehabilitation has been shown to be effective on low back pain, because it is based on the complex a...

Jul 30, 2020

Over the last few years, various concepts of applying core stabilisation mechanisms in the formation of human motor function have come to existence. The objective of the research was to assess the inf...

Jul 30, 2020

NPR2 encodes atrial natriuretic peptide receptor B (ANPRB), a regulator of skeletal growth. Biallelic loss-of-function mutations in NPR2 result in acromesomelic dysplasia Maroteaux type (AMDM; OMIM 60...

Jul 30, 2020

Genetic variation of insulin receptor substrate 1 (IRS-1) was found to modulate the insulin resistance of adipose tissues, but the underlying mechanism was not clear. To investigate how the IRS-1 was ...

Jul 30, 2020

Bone metastasis of prostate cancer is associated with pain and reduced overall survival (OS). Radium-223, which is expected to reduce bone pain and prolong OS, was recently approved in Japan.The aim o...

Jul 27, 2020

Low back pain (LBP) is a prevalent condition with overwhelming healthcare costs and high disability rates. Characterization of clinical and psychosocial variables over time in patients experiencing an...

Jul 27, 2020

To investigate the effect of supplementary energy on bone formation and resorption during arduous military training in energy deficit.Thirty male soldiers completed an 8-week military combat course (m...

Jul 27, 2020

Military service members commonly sustain lower extremity stress fractures (SFx). How SFx risk factors influence bone metabolism is unknown. Understanding how SFx risk factors influence bone metabolis...

Jul 27, 2020

Preclinical micro-CT provides a hotbed in which to develop new imaging technologies, including spectral CT using photon counting detector (PCD) technology. Spectral imaging using PCDs promises to expa...

Jul 27, 2020

As the percentage of overweight individuals in the population rises, diseases associated with excess weight resulting from poor nutrition are becoming more and more widespread. So far, the influence o...

Jul 27, 2020

Diamond-Blackan anemia (DBA) is the first ribosomopathy described and one of the constitutional inherited bone marrow failure syndromes. Erythroblastopenia is the major characteristic feature of the d...

Jul 23, 2020

Investigations on movement quality deficits associated with jump landing are numerous, however, these studies are often performed in laboratories with little distraction to the participant. This is co...