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Orthopedics General

Cortical thinning and accumulation of large cortical pores in the tibia reflect local structural deterioration of the femoral neck.

May 26, 2020

Cortical bone thinning and a rarefaction of the trabecular architecture represent possible causes of increased femoral neck (FN) fracture risk. Due to X-ray exposure limits, the bone microstructure is...

Acute Total Knee Replacement in Rheumatoid Arthritis Patients with Proximal Tibial Fractures: A Case Series.

May 26, 2020

Management of proximal tibial fractures is a challenging issue in patients with rheumatoid arthritis (RA). In the present study, we aimed to describe our experience of acute total knee replacement in ...

A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans.

May 26, 2020

Loss-of-function mutations in the COL2A1 gene were previously described as a cause of type II collagenopathy (e.g., spondyloepiphyseal dysplasia, Stickler syndrome type I), a major subgroup of genetic...

Surface modified and activated waste bone char for rapid and efficient VOCs adsorption.

May 26, 2020

In this work, very efficient VOCs adsorbent was developed from waste bovine bone. After pyrolysis at 450 °C, the bone char was treated by HPO for surface modification and activated by KCO respective...

Heterotopic Transplantation of Allogeneic Vertical Rectus Abdominis Myocutaneous Flaps in Miniature Swine.

May 26, 2020

Vascularized composite tissue allotransplantation (VCA) opens new possibilities for reconstruction of complex tissue defects, including upper extremity and facial transplantation. The main challenges ...

Inhibitory effect of the TSG-6 on the BMP-4/Smad signaling pathway and odonto/osteogenic differentiation of dental pulp stem cells.

May 26, 2020

This study aimed to observe the molecular mechanism underlying the effect of tumor necrosis factor-inducible protein 6 (TSG-6) on the bone morphogenetic protein-4 (BMP-4)/drosophila mothers against de...

Classic and targeted anti-leukaemic agents interfere with the cholesterol biogenesis metagene in acute myeloid leukaemia: Therapeutic implications.

May 26, 2020

Despite significant advances in deciphering the molecular landscape of acute myeloid leukaemia (AML), therapeutic outcomes of this haematological malignancy have only modestly improved over the past d...

Diaphragm Ultrasound: A Novel Approach to Assessing Pulmonary Function in Patients With Traumatic Rib Fractures.

Apr 14, 2020

Rib fractures following blunt trauma are a major cause of morbidity. Various factors have been used for risk stratification for complications. Ultrasound (US) measurements of diaphragm thickness (Tdi)...

Complications and Outcome after Rib Fracture Fixation: A Systematic Review.

Apr 14, 2020

In recent years, there has been a growing interest in operative treatment for multiple rib fractures and flail chest. However, to date, there is no comprehensive study that extensively focused on the ...

Systematic prospective electrophysiological studies of the median nerve after simple distal radius fracture.

Apr 14, 2020

To assess whether there is a measurable impairment of median nerve conduction study parameters with uncomplicated distal radius fracture.Patients were assessed prospectively at the time of cast remova...

Fracture Toughness Comparison of Three Indirect Composite Resins Using 4-Point Flexural Strength Method.

Apr 14, 2020

 The advantages of indirect composite restorations such as less crack formation during their computer-aided design/computer-aided manufacturing process, compared with ceramic restorations, have resu...

X-ray fluorescence microscopy: A method of measuring ion concentrations in the ear.

Apr 14, 2020

This technical note describes synchrotron x-ray fluorescence microscopy (XFM) as a method for measuring the concentrations of different elements in cross-sections of the ear at extremely high resoluti...

Posterior atlantoaxial facet joint reduction, fixation and fusion as revision surgery for failed suboccipital decompression in patients with basilar invagination and atlantoaxial dislocation: Operative nuances, challenges and outcomes.

Apr 14, 2020

To report the technical nuances and clinical outcomes of posterior atlantoaxial facet joint reduction, fixation and fusion (AFRF) technique as a revision procedure for BI and AAD patients with failed ...

Qualitative Assessment of Four Types of Three-Dimensional Printed Anatomical Tibial Bone Models Compared to Commercially Available Models.

Apr 14, 2020

 The aim of this study was to compare technical and physical features of four three-dimensional printed bone models used for teaching purposes to commercial models. A canine tibia was imaged using...

Osteoidosis leads to altered differentiation and function of osteoclasts.

Apr 14, 2020

In patients with osteomalacia, a defect in bone mineralization leads to changed characteristics of the bone surface. Considering that the properties of the surrounding matrix influence function and di...

Mesenchymal stem cells alleviate rat diabetic nephropathy by suppressing CD103 DCs-mediated CD8 T cell responses.

Apr 14, 2020

Diabetic nephropathy (DN) as a kind of serious microvascular complication of Diabetes Mellitus (DM) usually causes the end-stage of renal disease (ESRD). Studies have demonstrated that CD103 dendritic...

Polyetheretherketone Versus Titanium Cages for Posterior Lumbar Interbody Fusion: Meta-Analysis and Review of the Literature.

Apr 07, 2020

Lumbar fusion with implantation of interbody cage is a common procedure for treatment of lumbar degenerative disease. This study aims to compare the fusion and subsidence rates of titanium (Ti) versus...

The Influence of Mechanic Factors in Disc Degeneration Disease as a Determinant for Surgical Indication.

Apr 07, 2020

Low back pain is the most common reason for physician visit in Western population. It's one of the factors that affect health-related quality of life. Intervertebral disc degeneration is one of the le...

Reinforcing interpenetrating network hydrogels with 3D printed polymer networks to engineer cartilage mimetic composites.

Apr 07, 2020

Engineering constructs that mimic the complex structure, composition and biomechanics of the articular cartilage represents a promising route to joint regeneration. Such tissue engineering strategies ...

Modulation of bone formation and resorption using a novel ZOL loaded gelatin NPs integrated porous titanium scaffold: An in vitro and in vivo study.

Apr 07, 2020

Osteoporotic bone defect is a major challenge in clinics for bone regeneration. Under the condition of osteoporosis, excessive bone absorption and impaired osteogenesis resulted in unexpected long hea...

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