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Orthopedics General

Prolyl endopeptidase remodels macrophage function as a novel transcriptional coregulator and inhibits fibrosis.

Jul 03, 2023

Macrophages are immune cells crucial for host defense and homeostasis maintenance, and their dysregulation is involved in multiple pathological conditions, such as liver fibrosis. The transcriptional ...

Study on the infrared dynamic evolution characteristics of different joint inclination phyllite under uniaxial compression.

Jun 19, 2023

The destructive behavior of rocks and the evolution behavior of cracks are highly correlated. With the continuous development process of crack, the stress state of rock is constantly broken until enti...

Percutaneous pedicle screw fixation with percutaneous endoscopic transforaminal lumbar interbody fusion in the treatment of degenerative lumbar spondylolisthesis with instability.

Jun 12, 2023

To evaluate the safety and efficacy of percutaneous endoscopic transforaminal lumbar interbody fusion (PE-TLIF) in patients with L4-L5 degenerative lumbar spondylolisthesis (DLS) with instability.The ...

Fracture strength and bonding interface morphology of CAD/CAM-fabricated ceramic laminate veneers on bleached enamel treated with two different antioxidants.

Jun 12, 2023

This study aimed to investigate the effects of two antioxidants and their application time on the fracture strength of computer-aided design and computer-aided manufacturing (CAD/CAM)-fabricated ceram...

Pharmacokinetic Interaction between Rifampicin and Clindamycin in Staphylococcal Osteoarticular Infections.

Jun 12, 2023

The oral combination of clindamycin and rifampicin is relevant for the treatment of staphylococcal osteoarticular infections (SOAI). However, rifampicin induces CYP3A4, suggesting a pharmacokinetic (P...

Lead exposure of mainland Australia's top avian predator.

Jun 12, 2023

Lead (Pb) toxicity, through ingestion of lead ammunition in carcasses, is a threat to scavenging birds worldwide, but has received little attention in Australia. We analyzed lead exposure in the wedge...

Effects of ceramic type, connector dimension, and thermomechanical-aging on the fracture resistance and fit of CAD-CAM produced inlay-retained fixed partial dentures.

Jun 05, 2023

The purpose of the present study is to evaluate the fracture resistance and the fit of CAD-CAM produced inlay-retained fixed partial dentures. Eighteen experimental groups were generated according to ...

effects of monophosphoryl lipid A and Poly I:C combination on equine cells.

Jun 05, 2023

Toll-like receptor (TLR) agonists have been used as adjuvants to modulate immune responses in both animals and humans.The objective of this study was to evaluate the combined effects of the TLR 4 agon...

Risk of pathological fracture and paralysis during rehabilitation for patients with bone metastases: A questionnaire-based study.

Jun 05, 2023

Bone metastases can cause severe pain, pathological fractures, and spinal cord paralysis, which interrupt treatment for tumors and cause patients to be bedridden. In this study, we aimed to clarify th...

Fabricating super tough polylactic acid based composites by interfacial compatibilization of imidazolium polyurethane modified carbon nanotubes.

May 29, 2023

The interfacial compatibilization and dispersion of carbon nanotubes (CNTs) in incompatible poly(lactic acid)/poly(butylene terephthalate adipate) (PLA/PBAT) composites are key points for evaluating t...

Clinical performance of two onlay designs for molars after root canal treatment.

May 29, 2023

To evaluate the clinical performance of two proposed onlay designs.Molars with occlusal and/or mesial/distal defects after root canal treatment were classified by design into three groups. Onlays with...

A nested case-control study of factors contributing to the development of medication-related osteonecrosis of the jaw in patients using bone resorption inhibitors in Mishima City.

May 29, 2023

Medication-related osteonecrosis of the jaw (MRONJ) is characterized by necrosis of the jawbone with intraoral bacterial infection and has a significant negative impact on oral health-related quality ...

Shared Decision-Making in Athletes Diagnosed with a Cardiovascular Condition: A Scoping Review.

May 22, 2023

This scoping review summarizes existing approaches, benefits, and barriers to shared decision-making (SDM) in the context of sports cardiology. Among 6,058 records screened, 37 articles were included ...

Assessment of gastrointestinal health in racing Alaskan sled dogs using capsule endoscopy and inflammatory cytokines.

May 22, 2023

Exercise-induced gastrointestinal syndrome occurs in dogs and people and might compromise athlete performance by increasing intestinal permeability and causing gastrointestinal erosions. Racing sled d...

Tough and stretchable all-κ-carrageenan hydrogel based on the cooperative effects between chain conformation transition and stepwise mechanical training.

May 15, 2023

The traditional κ-carrageenan (κCG)-based hydrogel obtained from hot water can rupture easily under mechanical loading. To address this vulnerability, here we presented a robust all-κCG hydrogel wi...

Hemostasis-osteogenesis integrated Janus carboxymethyl chitin/hydroxyapatite porous membrane for bone defect repair.

May 15, 2023

Barrier membranes with osteogenesis are desirable for promoting bone repair. Janus membrane, which has a bilayered structure with different properties on each side, could meet the osteogenesis/barrier...

The Potency of Platelet-Rich Plasma for Chronic Low Back Pain: A Systematic Review and Metaanalysis of Randomized Controlled Trial.

May 15, 2023

Low back pain is one of the leading causes of disability in the world. Regenerative medicine can be one of the novel treatment breakthroughs in patients with low back pain, yet its use is still debata...

New Insights into Calorie Restriction Induced Bone Loss.

May 08, 2023

Caloric restriction (CR) is now a popular lifestyle choice due to its ability in experimental animals to improve lifespan, reduce body weight, and lessen oxidative stress. However, more and more emerg...

Concomitant valgus hip osteotomy in operative fixation of displaced proximal femoral neck fractures.

May 08, 2023

Total hip arthroplasty (THA) is considered the preferred treatment for displaced proximal femoral neck fractures. However, in many countries this option is economically unviable. To improve outcomes i...

Orbital wall restoration with primary bone fragments in complex orbital fractures.

May 08, 2023

Complex orbital fractures are impure orbital fractures because they involve the orbital walls and mid-facial bones. The author reported an orbital wall restoration technique in which the primary orbit...

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