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Orthopedics

NSAIDs May Interfere With Efficacy of Bisphosphonates

Apr 22, 2022

FRIDAY, April 22, 2022 (HealthDay News) -- The efficacy of the bisphosphonate clodronate for reducing osteoporotic fracture risk appears to be negated in adults using nonsteroidal anti-inflammatory dr...

Guideline Issued for Preventing SSI After Major Extremity Trauma

Apr 22, 2022

FRIDAY, April 22, 2022 (HealthDay News) -- In an evidence-based clinical practice guideline published by the American Academy of Orthopaedic Surgeons, recommendations are presented for the prevention ...

Sex Hormone Deficiency May Up Risk for Rotator Cuff Repair

Apr 21, 2022

THURSDAY, April 21, 2022 (HealthDay News) -- Sex hormone deficiency is associated with an increased incidence of rotator cuff repair (RCR), according to a study published online April 12 in the Journa...

Use of Extrapolation Common in FDA New Drug Approvals

Apr 19, 2022

TUESDAY, April 19, 2022 (HealthDay News) -- Extrapolation from pivotal trial data to broader U.S. Food and Drug Administration (FDA)-approved indications is common, according to a study published onli...

Health Supervision Discussed for Children With Down Syndrome

Apr 18, 2022

MONDAY, April 18, 2022 (HealthDay News) -- In a clinical report published online April 18 in Pediatrics, guidelines are presented for the health supervision of children and adolescents with Down syndr...

Vijoice Granted First Approval for Treatment of PROS

Apr 18, 2022

MONDAY, April 18, 2022 (HealthDay News) -- Vijoice (alpelisib) has been granted accelerated approval for severe PIK3CA-related overgrowth spectrum (PROS), the U.S. Food and Drug Administration announ...

Odontoid fracture complicating ankylosing spondylitis presenting with cervical canal stenosis and quadriparesis: A case report with 5-year follow-up and review of the literature.

Apr 18, 2022

Spinal fractures, especially cervical fractures, are more common in patients with ankylosing spondylitis in comparison with unaffected patients. However, odontoid fractures are relatively rare in thes...

Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.

Apr 18, 2022

Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. Circulating free (cfDNA) and circulating tumour DNA (ctDNA) are promising biomarkers for disease surveillance and ...

Bariatric Surgery Before TKA Cuts Complications in Obese Patients

Apr 15, 2022

FRIDAY, April 15, 2022 (HealthDay News) -- People with severe obesity and knee osteoarthritis are advised to attempt weight loss before total knee arthroplasty (TKA) as it could reduce complications o...

Osteopathic Manipulation May Be Effective for Musculoskeletal Conditions

Apr 14, 2022

THURSDAY, April 14, 2022 (HealthDay News) -- Osteopathic manipulative treatment (OMT) may be effective for musculoskeletal disorders, according to a review published online April 12 in BMJ Open.Donate...

Standard Treatments Comparable for Achilles' Tendon Rupture

Apr 14, 2022

THURSDAY, April 14, 2022 (HealthDay News) -- Patient-reported outcomes at 12 months are similar for open-repair, minimally invasive surgery, or nonoperative treatment of Achilles' tendon rupture, acco...

Shorter Prophylactic Antibiotics Feasible After Clean Orthopedic Surgery

Apr 12, 2022

MONDAY, April 12, 2022 (HealthDay News) -- Shorter antimicrobial prophylaxis duration is noninferior in preventing health care-associated infections following clean orthopedic surgery, according to a ...

Less Than Half of U.S.-Based Clinical Trials Report Race/Ethnicity

Apr 11, 2022

MONDAY, April 11, 2022 (HealthDay News) -- Less than half of U.S.-based trials report on race/ethnicity, and the median combined enrollment of minority race/ethnicity groups is below census estimates,...

Assessment of complications associated with casting of acute distal radius fractures in adults.

Apr 11, 2022

Controversy exists regarding the closed treatment of distal radius fractures. Circumferential casting of acute distal radius fractures has been shown to be safe in children, however, little research h...

Higher stress and symptom severity are associated with worse depressive symptom profiles in patients receiving chemotherapy.

Apr 11, 2022

In a sample of oncology patients, identify subgroups of patients with distinct depressive symptom profiles and evaluate for differences in demographic and clinical characteristics, levels of stress an...

Lived experience of State-sponsored intra-national overseas therapeutic mobility for stem cell transplantation.

Apr 11, 2022

This article focuses on the lived experience of patients with haematological cancer who were transferred from La Réunion (a French overseas Department) to mainland France to undergo allogeneic haemat...

How we approach the treatment of patients with high-risk neuroblastoma with naxitamab: experience from the Hospital Sant Joan de Déu in Barcelona, Spain.

Apr 11, 2022

Naxitamab [humanized 3f8 (hu3F8)] is a humanized monoclonal antibody (mAb) targeting the disialoganglioside GD2. It was approved in 2020 by the United States Food and Drug Administration (FDA) in com...

Intra-Articular Injection of Triamcinolone Beneficial in Hip Osteoarthritis

Apr 08, 2022

FRIDAY, April 8, 2022 (HealthDay News) -- For patients with hip osteoarthritis and at least moderate pain, an ultrasound-guided intra-articular hip injection of corticosteroid and local anesthetic, ad...

Psychological Interventions + Physical Therapy Ease Chronic Low Back Pain

Apr 07, 2022

THURSDAY, April 7, 2022 (HealthDay News) -- For people with chronic, nonspecific low back pain, psychological interventions are most effective when delivered in conjunction with physical therapy care ...

Despite Improvements, Disparities in Faculty Diversity Persist

Apr 07, 2022

THURSDAY, April 7, 2022 (HealthDay News) -- From 1977 to 2019, there was an increase in the representation of women compared with men at U.S. medical faculties, while representation of persons underre...

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