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Orthopedics

SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination.

Feb 12, 2024

We here demonstrate that SERTAD1 is an adaptor protein responsible for the regulation of lysine 63 (K63)-linked NLRP3 polyubiquitination by the Cullin1 E3 ubiquitin ligase upon inflammasome activation...

In OAB, Nocturnal Urinary Frequency Tied to Bruises, Fractures From Falls

Feb 05, 2024

FRIDAY, Feb. 2, 2024 (HealthDay News) -- For patients with overactive bladder (OAB), increasing nocturnal urination frequency is a common risk factor for falls with bruises and fractures, according t...

Thoracic spine X-ray examination of patients with back pain using different breathing technique and exposure times - A diagnostic study.

Feb 05, 2024

The breathing and suspended inspiration techniques are often used interchangeably for spine X-ray examinations. However, these techniques are not always adequately supported by clinical evidence. This...

A CRISPR base editing approach for the functional assessment of telomere biology disorder-related genes in human health and aging.

Feb 05, 2024

Telomere Biology Disorders (TBDs) are a group of rare diseases characterized by the presence of short and/or dysfunctional telomeres. They comprise a group of bone marrow failure syndromes, idiopathic...

Iodine Povacrylex Antisepsis Beneficial for Closed Extremity Fractures

Feb 02, 2024

THURSDAY, Feb. 1, 2024 (HealthDay News) -- For patients with closed extremity fractures, fewer surgical site infections occur with use of antisepsis with iodine povacrylex in alcohol, according to a ...

Shock Wave Therapy + Local Vibration Beneficial for Chronic Plantar Fasciitis

Jan 31, 2024

TUESDAY, Jan. 30, 2024 (HealthDay News) -- For patients with chronic plantar fasciitis, extracorporeal shock wave therapy combined with local vibration (ESWT-LV) is effective compared with ESWT alone...

Living Kidney Donors Have Lower Rates of Fractures Overall

Jan 31, 2024

TUESDAY, Jan. 30, 2024 (HealthDay News) -- During a mean follow-up of 25 years, living kidney donors have a lower rate of overall fractures compared with eligible nondonor controls, according to a st...

Practitioner Empathy Interventions Can Improve Patient Satisfaction

Jan 30, 2024

MONDAY, Jan. 29, 2024 (HealthDay News) -- Health care practitioner empathy interventions seem to improve patient satisfaction, but inadequate reporting hinders the ability to draw definitive conclusi...

Robotic-Assisted Joint Replacement Beneficial for Revision TKA

Jan 29, 2024

FRIDAY, Jan. 26, 2024 (HealthDay News) -- A robotic-assisted joint replacement is beneficial for revision total knee arthroplasties (TKAs), according to a study published in the February issue of Art...

Comparison of clinical outcomes and complications between endoscopic and minimally invasive transforaminal lumbar interbody fusion for lumbar degenerative diseases: a systematic review and meta-analysis.

Jan 29, 2024

This study compares the efficacy and complications of endoscopic transforaminal lumbar fusion (Endo-TLIF) and minimally invasive transforaminal lumbar fusion (MIS-TLIF) in treating lumbar degenerative...

A case of hepatocellular carcinoma with pseudoaneurysm formation upon lenvatinib administration.

Jan 29, 2024

A 79-year-old man received treatment for multiple intrahepatic hepatocellular carcinoma with atezolizumab + bevacizumab. However, he developed lower back pain attributed to spinal metastases upon ...

Denosumab Linked to Severe Hypocalcemia in Dialysis-Dependent Seniors

Jan 26, 2024

THURSDAY, Jan. 25, 2024 (HealthDay News) -- For female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or ve...

Advice Plus Physical Therapy No Better Than Just Advice for Shoulder Dislocation

Jan 26, 2024

THURSDAY, Jan. 25, 2024 (HealthDay News) -- For adults with a first-time traumatic shoulder dislocation, advice plus physical therapy appears to be no better than advice with the option to self-refer...

Self-Reported Walking Limitation Increases Five-Year Fracture Risk

Jan 25, 2024

WEDNESDAY, Jan. 24, 2024 (HealthDay News) -- Walking limitation is significantly associated with five-year fracture risk, according to a study published online Jan. 23 in JAMA Network Open.Dana ...

Improvements in Acute, Subacute Low Back Pain Seen Within First Six Weeks

Jan 23, 2024

MONDAY, Jan. 22, 2024 (HealthDay News) -- Patients with acute and subacute low back pain experience considerable improvements in pain and disability within the first six weeks, according to a review ...

Material-Intrinsic NIR-Fluorescence Enables Image-Guided Surgery for Ceramic Fracture Removal.

Jan 22, 2024

Hip arthroplasty effectively treats advanced osteoarthritis and has therefore been entitled as "operation of the 20th century." With demographic shifts, the USA alone is projected to perform up to 850...

Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair.

Jan 22, 2024

Magnesium is a revolutionary biomaterial for orthopedic implants, owing to its eminent mechanical properties and biocompatibility. However, its uncontrolled degradation rate remains a severe challenge...

A comparison of continuous cold flow and compression device and traditional icing regimen and no icing following anterior cruciate ligament reconstruction: A pilot study.

Jan 15, 2024

The aim of this study was to investigate the effectiveness of continuous cold flow and compression device as against traditional icing regimen and without icing after anterior cruciate ligament (ACL) ...

Complications related to unwitnessed magnet ingestion in paediatrics: Case series.

Jan 15, 2024

Foreign body inges tion is one of the mo s t common problems a mo ng chi ldren. There is a great te ndency among children between the age of six months to six years to p lace objects, such as coins, f...

Association of ACE*(Insertion/Deletion) Variant with the Elevated Risk of Preeclampsia Among Gestational Women.

Jan 15, 2024

The renin-angiotensin-aldosterone system has an indispensable function in the uteroplacental circulation, placental growth, and blood pressure optimization. The angiotensin I converting enzyme (ACE) g...

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