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Orthopedics

Human Umbilical Cord Mesenchymal Stem Cell-induced Osterix, Bone Morphogenetic Protein-2, and Tartrate-resistant Acid Phosphatase Expression in Osteoporotic Mandibular Bone.

Sep 10, 2020

 The aim of this study was to prove that human umbilical cord mesenchymal stem cell (hUCMSC) therapy conducted according to the mandibular osteoporotic model will increase Osterix (Osx) and bone mor...

Effect of Geometry on the Fixation Strength of Anterior Cruciate Ligament Reconstruction Using BASHTI Technique.

Sep 10, 2020

The goal of this study is to investigate the effects of tendon and cannulated drill bit diameter on the strength of the bone and site hold tendon inside (BASHTI) fixation technique for an anterior cru...

Ginsenoside Rg3 attenuates ovariectomy-induced osteoporosis via AMPK/mTOR signaling pathway.

Sep 10, 2020

Ginsenoside Rg3, a ginsenoside isolated from Panax ginseng, can regulate autophagy via AMP-activated protein kinase/mammalian target of rapamycin (AMPK/mTOR) signaling pathway. AMPK/mTOR signaling and...

Effect of Chronic Alcoholism on Traumatic Intracranial Hemorrhage.

Sep 07, 2020

Traumatic Intracranial hemorrhage (TICH) is one of the commonest indications for neurosurgical consultation following trauma. Worsening neurological exam, size of initial TICH, presence of displaced s...

Passive stiffness characteristics and neutral zone quality of the scoliotic lumbar torso in the principle anatomical planes of motion.

Sep 07, 2020

The 1-10% prevalence rate of adult scoliosis frequently requires expensive therapy and surgical treatments and demands further research into the disease, especially with an aging population. Most stud...

A joint kinematics driven model of the pelvic soft tissue artefact.

Sep 07, 2020

When skin-markers trajectories are used in human movement analysis, compensating for their relative movement with respect to the underlying bone (soft tissue artefact, STA) is essential for accurate b...

Pentraxin 3 inhibits fibroblast growth factor 2 induced osteoclastogenesis in rheumatoid arthritis.

Sep 07, 2020

Synovial fibroblasts (SFs) act as key effector cells mediating synovial inflammation and joint destruction in rheumatoid arthritis (RA). Fibroblast growth factor 2 (FGF2) and its receptors (FGFRs) pla...

Evaluating the mechanical response of novel synthetic femurs for representing osteoporotic bone.

Sep 07, 2020

Osteoporosis is a disease prevalent in older adults, characterized by high porosity in bone and subsequent decrease in fracture resistance. This demographic is also the population that most frequently...

Back pain outcomes after minimally invasive anterior lumbar interbody fusion: a systematic review.

Sep 03, 2020

Minimally invasive anterior lumbar interbody fusion surgery (MIS ALIF) is a technique that restores disc height and lumbar lordosis through a smaller exposure and less soft-tissue trauma compared to o...

Minimally invasive lateral corpectomy for thoracolumbar traumatic burst fractures.

Sep 03, 2020

The need for anterior column reconstruction after thoracolumbar burst fractures remains controversial. Here, the authors present their experience with minimally invasive lateral thoracolumbar corpecto...

PEEK versus titanium cages in lateral lumbar interbody fusion: a comparative analysis of subsidence.

Sep 03, 2020

The authors have provided a review of radiographic subsidence after lateral lumbar interbody fusion (LLIF) as a comparative analysis between titanium and polyetheretherketone (PEEK) cages. Many author...

Radiologic comparative analysis between saline and platelet-rich fibrin filling after hydraulic transcrestal sinus lifting without adjunctive bone graft: A randomized controlled trial.

Sep 03, 2020

To evaluate implant survival rate, any complications, and changes of residual alveolar bone height (RABH) using saline or platelet-rich fibrin (PRF) filling after hydraulic transcrestal sinus lifting....

Mechanism of miRNA-based Aconitum leucostomum Worosch. Monomer inhibition of bone marrow-derived dendritic cell maturation.

Sep 03, 2020

Delvestidine (DLTD) is a monomeric compound isolated from Aconitum leucostomum Worosch, a widely used medicine for local treatment of rheumatoid arthritis (RA). Studies have shown that Aconitum leucos...

Mini-open lateral retropleural/retroperitoneal approaches for thoracic and thoracolumbar junction anterior column pathologies.

Sep 03, 2020

Advancements in less invasive lateral retropleural/retroperitoneal approaches aim to address the limitation of posterolateral approaches and avoid complications associated with anterior open thoracoto...

Low Back Pain Also May Resolve in Some After Hip Replacement

Sep 01, 2020

FRIDAY, July 10, 2020 (HealthDay News) -- Symptomatic low back pain (LBP) resolves in 82 percent of patients with hip and back pain who undergo total hip arthroplasty (THA), according to a study prese...

Lung-Specific Risk Factors Linked to Hip Fracture in Smokers

Aug 31, 2020

MONDAY, Aug. 31, 2020 (HealthDay News) -- The addition of lung-specific risk factors into fracture risk assessment tools may more accurately predict hip fracture risk in smokers, according to a study ...

Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents.

Aug 31, 2020

Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) as major cause of chronic low back pain represent the most common degenerative joint pathologies and are leading causes of pain and disa...

Cartilage and Subchondral Bone Distributions of the Distal Radius: A 3-Dimensional Analysis Using Cadavers.

Aug 31, 2020

To quantify the spatial distributions of cartilage and subchondral bone thickness of the distal radius.Using 17 cadaveric wrists, three types of 3-dimensional models were created: a cartilage-bone mod...

Stretchable, tough and elastic nanofibrous hydrogels with dermis-mimicking network structure.

Aug 31, 2020

Nanofiber-structured hydrogels with robust mechanical properties are promising candidates for the development of multifunctional materials in advanced fields. However, creating such materials that com...

Bio-inspired surface modification of PEEK through the dual cross-linked hydrogel layers.

Aug 31, 2020

The biocompatible high-performance material PEEK (polyetheretherketone) is an attractive implant material, however, its hydrophobicity and high friction coefficients severely hinder its biomedical app...

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