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Orthopedics

Sickle cell disease clinical phenotypes in Nigeria: A preliminary analysis of the Sickle Pan Africa Research Consortium Nigeria database.

Jun 08, 2020

Sickle cell disease (SCD) is a monogenic disease with multiple phenotypic expressions. Previous studies describing SCD clinical phenotypes in Nigeria were localized, with limited data, hence the need ...

Biomechanical comparison of anterior cruciate ligament repair with internal brace augmentation versus anterior cruciate ligament repair without augmentation.

Jun 08, 2020

Newer repair techniques of anterior cruciate ligament tears, including augmentation with internal brace, have shown promising clinical results. Few biomechanical studies exist comparing anterior cruci...

Staurosporine and venetoclax induce the caspase-dependent proteolysis of MEF2D-fusion proteins and apoptosis in MEF2D-fusion (+) ALL cells.

Jun 08, 2020

MEF2D-fusion (M-fusion) genes are newly discovered recurrent gene abnormalities that are detected in approximately 5 % of acute lymphoblastic leukemia (ALL) cases. Their introduction to cells has been...

Postoperative Lung Complications Common in Patients With SARS-CoV-2

Jun 05, 2020

FRIDAY, June 5, 2020 (HealthDay News) -- About half of patients with perioperative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have postoperative pulmonary complications, which are as...

Minimum clinically important difference of major patient-reported outcome measures in patients undergoing decompression surgery for lumbar spinal stenosis.

Jun 04, 2020

A minimum clinically important difference (MCID) has been increasingly well known in the current era of patient-centered care because it reflects a smallest change that is meaningful for patients foll...

The Effect of Divided Attention with Bounce Drop Jump on Dynamic Postural Stability.

Jun 04, 2020

This study determined the effect of divided attention on controlling postural stability during a drop vertical jump task. In total, 30 participants were tested for drop vertical jumps from a 30-cm hig...

A comparative study of materials assembled from recombinant K31 and K81 and extracted human hair keratins.

Jun 04, 2020

Natural biopolymers have found success in tissue engineering and regenerative medicine applications. Their intrinsic biocompatibility and biological activity make them well suited for biomaterials dev...

Associations between Proton Pump Inhibitor and Histamine-2 Receptor Antagonist and Bone Mineral Density among Kidney Transplant Recipients.

Jun 04, 2020

In the general population, use of proton pump inhibitor (PPI) has been linked to higher risk of osteoporotic fractures. PPI is commonly prescribed in kidney transplant recipients (KTRs). However, the ...

Stem cell mobilization with plerixafor and healing of diabetic ischemic wounds: A phase IIa, randomized, double-blind, placebo-controlled trial.

Jun 04, 2020

Bone marrow-derived cells contribute to tissue repair, but traffic of hematopoietic stem/progenitor cells (HSPCs) is impaired in diabetes. We therefore tested whether HSPC mobilization with the CXCR4 ...

May 2020 Briefing - Orthopedics

Jun 01, 2020

Here are what the editors at HealthDay consider to be the most important developments in Orthopedics for May 2020. This roundup includes the latest research news from journal articles, as well as the ...

Dextrose Injections Aid Knee Osteoarthritis Pain

Jun 01, 2020

MONDAY, June 1, 2020 (HealthDay News) -- Intra-articular dextrose prolotherapy (DPT) injections are a safe and effective treatment for knee osteoarthritis, according to a study published in the May/Ju...

The Relationship Between Injury-Related Fear and Visuomotor Reaction Time in Individuals With a History of Anterior Cruciate Ligament Reconstruction.

Jun 01, 2020

Deficits in reaction time, decreased self-reported knee function, and elevated levels of injury-related fear have been observed in individuals who sustain anterior cruciate ligament injury. Understand...

Applying the Sport Commitment Model to Sport Injury Rehabilitation.

Jun 01, 2020

Sustaining effort and persistence throughout injury rehabilitation are common goals for sport health care professionals. Considerable research in the sport domain has explored the issue of commitment ...

Injuries in Collegiate Ladies Gaelic Footballers: A 2-Season Prospective Cohort Study.

Jun 01, 2020

Although Ladies Gaelic football is one of the most popular female sports in Ireland, just 2 previous injury surveillance studies have been completed, and both were retrospective in nature.To prospecti...

Analysis of carpal bones on MR images for age estimation: First results of a new forensic approach.

Jun 01, 2020

Current multifactorial age estimation methods are based on radiography, however, in the forensic field there is growing interest in using magnetic resonance imaging (MRI). With regard to the carpal re...

Laminins in osteogenic differentiation and pluripotency maintenance.

Jun 01, 2020

Extracellular matrix (ECM) plays an integral role in different developmental stages and in multiple systems. However, due to ECM being composed of various extracellular components (growth factors, cyt...

Metabolomics in the Development and Progression of rheumatoid arthritis: A Systematic Review.

Jun 01, 2020

A systematic review and analysis of data from several rheumatoid arthritis metabolomics studies attempts to determine which metabolites can be used as potential biomarkers for the diagnosis of rheumat...

Deferment of Elective Surgeries Due to COVID-19 Will Have Lasting Impact

May 30, 2020

FRIDAY, May 29, 2020 (HealthDay News) -- At two years after the end of the elective orthopedic surgery deferment related to the COVID-19 pandemic, there will be a cumulative backlog of more than 1 mil...

An Adjunct Indicator for the Diagnosis of Fracture-Related Infections: Platelet Count to Mean Platelet Volume Ratio.

May 28, 2020

Fracture-related infection (FRI) is a common complication associated with orthopaedic fracture care. Diagnosing these complications in the preoperative setting is difficult. Platelets are a known acu...

The effects of vitamin K-rich green leafy vegetables on bone metabolism: A 4-week randomised controlled trial in middle-aged and older individuals.

May 28, 2020

High vegetable intake is associated with beneficial effects on bone. However, the mechanisms remain uncertain. Green leafy vegetables are a rich source of vitamin K1, which is known to have large effe...

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