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Pain Management

Mean Cost of Bringing New Drug to U.S. Market Is $879.3 Million

Jul 03, 2024

TUESDAY, July 2, 2024 (HealthDay News) -- The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are consider...

Personal Experiences Through Chronic Neck and Low Back Pain

Jul 02, 2024

The following is a summary of “Chronic neck and low back pain from personal experiences: a written narrative approach,” published in the May 2024 issue of Pain by Sora, et al. Despite being...

Cost and Usage Patterns of Transdermal Patch and Buprenorphine Buccal Film for cLBP

Jul 01, 2024

The following is a summary of “Economic burden and dosing trends of buprenorphine buccal film and transdermal patch in chronic low back pain,” published in the May 2024 issue of Pain by Zah, et al...

Examining the Efficacy of WAA in Alleviating Moderate to Severe Postoperative Pain after FESS

Jun 28, 2024

The following is a summary of “Wrist and ankle acupuncture relief moderate to severe postoperative pain after functional endoscopic sinus surgery: A randomized controlled study,” published in the ...

Insights to Neuroimaging Biomarkers in Episodic Migraine for Response to NSAIDs

Jun 27, 2024

The following is a summary of “Exploring potential neuroimaging biomarkers for the response to non-steroidal anti-inflammatory drugs in episodic migraine,” published in the June 2024 issue of Pain...

Platelet Concentration in PRP Ineffective in Altering Pain Outcomes for Lateral Epicondylitis

Jun 27, 2024

The following is a summary of “Concentration of platelets in PRP does not affect pain outcomes in lateral epicondylitis: a systematic review and meta-analysis,” published in the June 2024 issue of...

Algorithm Validation for Predicting Response to M1-rTMS in Peripheral Neuropathic Pain

Jun 27, 2024

The following is a summary of “Prediction of the response to repetitive transcranial magnetic stimulation of the motor cortex in peripheral neuropathic pain and validation of a new algorithm,” pub...

Comparing EMS, IFC, and TENS Patient-Reported Outcomes in CLBP

Jun 27, 2024

The following is a summary of “Effect of EMS, IFC, and TENS on patient-reported outcome measures for chronic low back pain: a systematic review and meta-analysis,” published in the June 2024 issue...

Pediatric Surgical Opioid Prescribing Concentrated Among a Few Procedures

Jun 27, 2024

WEDNESDAY, June 26, 2024 (HealthDay News) -- Pediatric surgical opioid prescribing is concentrated among a small number of procedures, especially tonsillectomy and/or adenectomy, according to a study...

Atogepant Efficacious for Patients With Chronic Migraine

Jun 27, 2024

WEDNESDAY, June 26, 2024 (HealthDay News) -- For patients with chronic migraine (CM), with and without medication overuse, atogepant is efficacious, according to a study published online June 27 in N...

Topical TRPV1-Antagonist Gel Effectively Reduces Evoked Pain

Jun 26, 2024

The following is a summary of “Topically applied novel TRPV1 receptor antagonist, ACD440 Gel, reduces evoked pain in healthy volunteers, a randomized, double-blind, placebo-controlled, crossover stu...

Ensuring Safety of Adjunct Pre-operative IV S-Ketamine in Third Molar Surgery for Pain Relief

Jun 25, 2024

The following is a summary of “Patient safety of adjunct pre-operative intravenous S-ketamine for pain relief in third molar surgery – a randomised, placebo-controlled, double-blind trial,” publ...

Genetic Associations of IL18 Variants RS360717 and RS187238 with Migraine Diagnosis

Jun 24, 2024

The following is a summary of “IL18 rs360717 and rs187238 genetic variants are associated with migraine diagnosis,” published in the June 2024 issue of Pain by Vitali-Silva, et al. Genetics...

Distinguishing PTH in mTBI Through Insular Subdivision Connectivity

Jun 24, 2024

The following is a summary of “Connectivity of the insular subdivisions differentiates posttraumatic headache-associated from nonheadache-associated mild traumatic brain injury: an arterial spin lab...

Aromatherapy Reduces Catheter Insertion Pain

Jun 23, 2024

Rose oil aromatherapy and hand-holding reduced pain during peripheral intravenous catheter (PIVC) insertion, according to findings published in Explore. Tulay Basak and colleagues conducted a comparat...

Fremanezumab Effective and Tolerable in Migraine Prevention

Jun 21, 2024

The following is a summary of “Effectiveness of fremanezumab treatment in patients with migraine headache,” published in the June 2024 issue of Pain by Kikui, et al. Researchers conducted a...

High-Frequency Nerve Block Treatment Reduces Chronic Post-Amputation Pain, Improves QOL, and Decreases Opioid Use

Jun 21, 2024

The following is a summary of "Primary 3-Month Outcomes of a Double-Blind Randomized Prospective Study (The QUEST Study) Assessing Effectiveness and Safety of Novel High-Frequency Electric Nerve Block...

Factors Influencing Post-Operative Opioid Requirements for Tibial Fractures

Jun 21, 2024

The following is a summary of “What influences post-operative opioid requirements for tibial fractures?,” published in the June 2024 issue of Pain by Zhang, et al. The lack of specific opio...

Current Literature Evidence on High-Dose Intravenous L-Ascorbate in Pain Therapy

Jun 21, 2024

The following is a summary of “Use of High-Dose Intravenous L-Ascorbate in Pain Therapy: Current Evidence from the Literature: A prospective clinical study,” published in the June 2024 issue of Pa...

Adapting and Validating the DVPRS for Cross-Cultural Use in Acute and Chronic Pain

Jun 21, 2024

The following is a summary of “Cross-cultural adaptation and psychometric validation of the french version of the “defense and veterans pain rating scale” for acute and chronic pain: A prospecti...

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