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Pain Management

REN: A Novel Approach to Migraine Treatment

Apr 10, 2020

Evidence suggests that pharmacologic agents often used to treat migraine may at times be ineffective, poorly tolerated, contraindicated, and—if used too frequently—can cause possible medication ov...

Many Legal Marijuana Products Too Strong for Treating Pain

Apr 03, 2020

FRIDAY, April 3, 2020 (HealthDay News) -- Legally dispensed marijuana products have stronger concentrations of tetrahydrocannabinol (THC) and cannabidiol (CBD) than needed for chronic pain relief, acc...

External Trigeminal Nerve Stimulation for VM

Apr 01, 2020

Despite being the most common neurologic cause of vertigo in adults, no FDA-approved treatments are available for vestibular migraine (VM) and few studies have assesses possibly effective rescue treat...

Cannabis & Coronavirus: Is it a Good Idea? Medical Expert Dr. Verbora Explains

Mar 31, 2020

Throughout the United States, legislators and county officials are quickly escalating quarantines to prevent the spread of COVID-19.  Amid the panic, one industry is struggling to keep products in...

Inhaled Cannabis for Headache & Migraine

Mar 23, 2020

Today, a substantial proportion of medical cannabis users report using cannabis to manage headache and migraine, claiming that it is effective. However, research on the effectiveness of cannabis for t...

Lumbar Puncture Guidance

Mar 09, 2020

Data indicate that nearly 400,000 lumbar punctures (LPs) are performed annually for either diagnostic workup or therapeutic relief in the United States. Regular referral to radiology for assistance ...

Opioid Use After ED Visits for Acute Pain

Feb 26, 2020

While the frequency of short-term side effects of opioids are well-known, the long-term risks of opioid use are inadequately quantified. For a study published in Annals of Emergency Medicine, my colle...

nVNS for Vestibular Migraine

Feb 24, 2020

Although data indicate that vestibular migraine (VM) is the most common neurologic cause of vertigo in adults, no FDA-approved agents exist for its treatment. With few studies having pursued rescue tr...

Brain MRIs ID Racial Differences in Pain Response

Feb 11, 2020

TUESDAY, Feb. 11, 2020 (HealthDay News) -- Racial differences in pain may be rooted in life experience, rather than intrinsic biology, according to a study published online Feb. 3 in Nature Human Beha...

Multivariate spatiotemporal modeling of drug- and alcohol-poisoning deaths in New York City, 2009-2014.

Feb 04, 2020

Drug- and alcohol-poisoning deaths remain current public health problems. Studies to date have typically focused on individual-level predictors of drug overdose deaths, and there remains a limited und...

Illicit drug use among college students: The role of social norms and risk perceptions.

Feb 04, 2020

To examine the prevalence and correlates of college student use of illicit substances including cocaine, designer drugs, and nonmedical use of prescription stimulants and opioids, and to identify how ...

Pressure pain thresholds in children before and after surgery: a prospective study.

Feb 04, 2020

Background and aims This prospective study aimed to assess pressure pain thresholds (PPTs) by pressure algometry and the correlation to postoperative pain in children undergoing orthopaedic surgery. W...

CYP450-Mediated Metabolism of Mitragynine and Investigation of Metabolites in Human Urine.

Feb 04, 2020

Mitragyna speciosa (Kratom) has emerged as a recreational drug and a substance of medicinal intrigue. Although the drug was initially used recreationally for its sedating and euphoric effects, more re...

Proactive Pain Management May Cut Postop Opioid Prescriptions

Feb 03, 2020

MONDAY, Feb. 3, 2020 (HealthDay News) -- An enhanced recovery after surgery program complemented by a preemptive pain management program is associated with a decrease in opioid prescriptions at discha...

GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents.

Jan 31, 2020

Treating neuropathic pain is challenging and novel non-opioid based medicines are needed. Using unbiased receptomics, transcriptomic analyses, immunofluorescence and in situ hybridization, we found th...

Opioid Prescribing Behaviors - Prescription Behavior Surveillance System, 11 States, 2010-2016.

Jan 31, 2020

In 2017, a total of 70,237 persons in the United States died from a drug overdose, and 67.8% of these deaths involved an opioid. Historically, the opioid overdose epidemic in the United States has bee...

Achieving Opioid-Free Major Colorectal Surgery: Is It Possible?

Jan 31, 2020

Opioid analgesia remains the mainstay of postoperative pain management strategies despite being associated with many adverse effects. A specific opioid-free protocol was designed to limit opioid usage...

An 8-Year Retrospective Study on Suicides in Washington, DC.

Jan 31, 2020

The suicide rate in the United States has been increasing steadily over the previous 10 years. In DC, these results are not mirrored. The suicide rate has a tendency to be lower than the rest of the c...

Therapeutic Drug Monitoring in Buprenorphine/Naloxone Treatment for Opioid Use Disorder: Clinical Feasibility and Optimizing Assay Precision.

Jan 31, 2020

Compliance with sublingual buprenorphine/naloxone (SL-BUP/NX) is associated with higher abstinence from illicit opioid use. Therapeutic drug monitoring (TDM) has been recommended for adherence monitor...

Prognostic factors for improved physical and emotional functioning one year after interdisciplinary rehabilitation in patients with chronic pain: Results from a national quality registry in Sweden.

Jan 30, 2020

To investigate prognostic factors for physical and emotional functioning following interdisciplinary multimodal pain rehabilitation, by targeting patients' baseline characteristics and health measures...

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