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Pain General

Chronic Illness Patient Goals-of-Care Discussion Predictors

Feb 28, 2023

The following is a summary of the “Predictors of Documented Goals-of-Care Discussion for Hospitalized Patients With Chronic Illness,” published in the February 2023 issue of Pain and Symptom Manag...

Clinical differences in a multidisciplinary pediatric pain unit between primary and secondary chronic pain.

Feb 27, 2023

Chronic pain affects an important part of the pediatric population in developed countries. secondary chronic pain (SCP) can have a well-defined medical cause, but primary chronic pain (PCP) can have a...

Are catechol-O-methyltransferase gene polymorphisms genetic markers for pain sensitivity after all? - A review and meta-analysis.

Feb 27, 2023

The catechol-O-methyltransferase (COMT) gene has arguably been the designated pain sensitivity gene for nearly two decades. However, the literature provides inconsistent evidence. We performed several...

Dosimetric assessment of the mono and dual-isocentric VMAT technique based on flattening filter-free beams for SBRT with non-contiguous spinal targets.

Feb 27, 2023

The study aimed to evaluate the planning characteristics of spinal stereotactic body radiotherapy (SBRT) using mono- and dual-isocentric volumetrically modulated arc therapy (VMAT) techniques. The dos...

Spinal Cord Infarction With Prolonged Femoral Venoarterial Extracorporeal Membrane Oxygenation.

Feb 27, 2023

There have been sporadic reports of ischemic spinal cord injury (SCI) during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support. The authors observed a troubling pattern of this catast...

The Efficacy of Acceptance and Commitment Therapy for Chronic Pain: A Systematic Review and Meta-analysis.

Feb 27, 2023

Previous meta-analyses of a small number of trials showed that acceptance and commitment therapy (ACT) might improve chronic pain. Many new trials have been published afterward, and the factors that m...

Acute ostracism-related pain sensitization in the context of accumulated lifetime experiences of ostracism.

Feb 27, 2023

Ostracism (i.e., being ignored/ excluded) is a form of social adversity that powerfully impacts health and well-being. While laboratory research indicates that experimentally manipulated experiences o...

Cervical spine injuries in spinal ankylosing disorders: results of single-stage posterior stabilization without posterolateral fusion.

Feb 20, 2023

Patients with long-segment cervical spinal fusion resulting from spinal ankylosing disorders (SADs) are at high risk for highly unstable cervical spine fractures necessitating surgery as the treatment...

The roles of periaqueductal gray and dorsal raphe nucleus dopaminergic systems in the mechanisms of thermal hypersensitivity and depression in mice.

Feb 20, 2023

Depression and thermal hypersensitivity share pathogenic features and symptomology, but their pathophysiologic interactions have not been fully eluidated. Dopaminergic systems in the ventrolateral per...

Fecal microbiota transplantation revealed a pain-related gut microbiota community in ovariectomized mice.

Feb 20, 2023

Higher sensitivity to pain is a common clinical symptom in postmenopausal females. The gut microbiota (GM) has recently been identified as participating in various pathophysiological processes and may...

Transversus abdominis plane block in adult open liver surgery patients: A systematic review with meta-analysis of randomized controlled trials.

Feb 13, 2023

The objective of this meta-analysis is to evaluate the efficacy of Transversus Abdominis Plane Block (TAPB) in pain control and recovery after open hepatic surgery.We searched for the articles in PubM...

An investigation of the effects of connective tissue massage in women with migraine: A controlled clinical trial.

Feb 13, 2023

To investigate the effects of connective tissue massage (CTM) on pain characteristics, accompanying symptoms, medication usage, disability, sleep quality, psychological status, and quality of life in ...

Treating fibromyalgia with electrical neuromodulation: A systematic review and meta-analysis.

Feb 13, 2023

Several types of electrical neuromodulation (such as transcranial direct current stimulation, tDCS; transcutaneous electrical nerve stimulation) have been applied in the treatment of fibromyalgia. The...

Current attitudes toward carrier screening for spinal muscular atrophy among pregnant women in Eastern China.

Feb 13, 2023

Spinal muscular atrophy (SMA) is an autosomal recessive and often fatal neurological disease. However, very little is known about the attitudes toward SMA carrier screening among Chinese pregnant peop...

WISP-2 modulates the induction of inflammatory mediators and cartilage catabolism in chondrocytes.

Feb 13, 2023

Wnt-1 inducible signaling pathway protein 2 (WISP-2/CCN5) is a recently identified adipokine that has been described as an important mediator of canonical Wnt activation in adipogenic precursor cells....

Childhood-Onset Lupus Nephritis in the Childhood Arthritis and Rheumatology Research Alliance Registry: Short-Term Kidney Status and Variation in Care.

Feb 13, 2023

The goal was to characterize short-term kidney status and describe variation in early care utilization in a multicenter cohort of patients with childhood-onset systemic lupus erythematosus (cSLE) and ...

Positive childhood experiences and chronic pain among children and adolescents in the United States.

Feb 13, 2023

Positive childhood experiences (PCEs) are associated with better mental and physical health outcomes and moderate the negative effects of adverse childhood experiences (ACEs). However, knowledge of th...

Long-acting opioids and cardiovascular diseases: Help or hindrance!

Feb 06, 2023

Opioids are widely being used for chronic pain management, cough and diarrhea suppressants, anesthetic agents, and opioid de-addiction therapy. Opioid receptors, present in the central nervous system ...

[Chinese recommendations for the management of fibromyalgia syndrome].

Feb 06, 2023

Fibromyalgia syndrome (FMS) is a common clinical syndrome. At present, the lack of epidemiological data from large-sample studies in our country persists, and there are many difficulties in diagnosis ...

Corticospinal and spinal adaptations following lower limb motor skill training: a meta-analysis with best evidence synthesis.

Feb 06, 2023

Motor skill training alters the human nervous system; however, lower limb motor tasks have been less researched compared to upper limb tasks. This meta-analysis with best evidence synthesis aimed to d...

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