Feb 17, 2020

BACKGROUND The hepatotoxicity of Tripterygium wilfordii Hook. f. (TWHF) limits its clinic utilization. Qingluo Tongbi formula (QTF) was formulated based on a basic Chinese medicine theory. Previous st...

Feb 17, 2020

To develop an automated pipeline based on convolutional neural networks to segment lumbar intervertebral discs and characterize their biochemical composition using voxel-based relaxometry, and establi...

Feb 17, 2020

Pulsed radiofrequency (PRF) has been used successfully to treat myriad types of chronic pain, including spinal radicular pain and that associated with facet arthropathy. Although there are a few repor...

Feb 17, 2020

Modulation of pain perception by oxytocin (OXT) has attracted increased scientific and clinical interest. Neural mechanisms underlying these effects are poorly understood. In this study, we aimed to i...

Feb 13, 2020

Maintaining phosphorus balance in in-center hemodialysis (ICHD) patients is problematic despite recommended dietary restriction, dialysis, and phosphate binder use. Rarely is P content in prescribed m...

Feb 13, 2020

As a post-approval commitment, this dose-ranging study was undertaken to evaluate efficacy and safety of onabotulinumtoxinA in adolescents.In adolescents, migraine is often undiagnosed or misdiagnosed...

Feb 13, 2020

Migraine is one of the most common neurologic disorders in children and adolescents. However, a quantitative comparison of multiple preventive pharmacologic treatments in the pediatric population is l...

Feb 13, 2020

Galcanezumab is a novel monoclonal antibody that target to calcitonin gene-related peptide (CGRP). It has been tested for the preventive treatment of migraine and episodic cluster headache by multiple...

Feb 13, 2020

To describe a patient with migraine with aura (MWA) who was found to have a reversible lesion of the corpus callosum.Reversible lesions of the splenium of the corpus callosum are well-described clin...

Feb 13, 2020

: This study investigates the relationship between exposure to hot/cold weather and the characteristic clinical features of headaches in patients with migraine and tension-type headaches.: This cross-...

Feb 13, 2020

The Positive and Negative Affect Schedule (PANAS) is the most widely and frequently used scale to assess positive and negative affect. The PANAS has been validated in several languages, and it has sho...

Feb 13, 2020

The aim of this cross-sectional study is to determine the prevalence of opioid use in a large sample of fibromyalgia (FM) patients and examine the factors associated with opioid prescription/use despi...

Feb 13, 2020

This review identified prospective cohort studies in the general population which showed incidence (23 papers) and risk factors (37 papers) for fibromyalgia and chronic widespread pain. Median inciden...

Feb 13, 2020

 While total knee arthroplasty (TKA) is a reliable treatment for advanced knee arthritis, up to 19% of patients after TKA remain dissatisfied, especially with residual pain. A less known source of me...

Feb 13, 2020

Naltrexone and nalmefene are approved for the treatment of alcohol use disorders, in different countries. Naltrexone is also approved for the treatment for opioid use disorders, most recently in a dep...

Feb 13, 2020

Pain and emotional distress have a reciprocal relation. The amygdala has been implicated in emotional processing. The central nucleus of amygdala (CeA) receives nociceptive information from the dorsal...

Feb 13, 2020

Medications for opioid use disorder (OUD) are the most effective treatment for OUD, but uptake of these life-saving medications has been extremely limited in US prisons and jail settings, and limited ...

Feb 13, 2020

Long-term engagement in opioid agonist therapy (OAT) has been consistently associated with reduced risk for morbidity and mortality in people with opioid use disorder (OUD). However, the dynamic natur...

Feb 13, 2020

Rheumatoid arthritis (RA) is a systemic autoimmune and inflammatory disease. Our study aimed to determine the effect of saffron supplement on clinical outcomes and metabolic profiles in patients with ...

Feb 13, 2020

Numerous epidemiological studies have suggested a link between vitamin D deficiency and the development of various autoimmune diseases, including diabetes mellitus type 1, rheumatoid arthritis, inflam...