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Pain General

Effect of Incisional Negative Pressure Wound Therapy vs Standard Wound Dressing on Deep Surgical Site Infection After Surgery for Lower Limb Fractures Associated With Major Trauma: The WHIST Randomized Clinical Trial.

Feb 13, 2020

Following surgery to treat major trauma-related fractures, deep wound infection rates are high. It is not known if negative pressure wound therapy can reduce infection rates in this setting.To assess ...

Alterations in pronociceptive and antinociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis.

Feb 13, 2020

Altered pronociceptive and antinociceptive mechanisms are often implicated in painful conditions and have been increasingly studied over the past decade. For some painful conditions, alterations are w...

Exploring the neural correlates of touch and pain in women with provoked vestibulodynia.

Feb 13, 2020

Group differences in touch and pain thresholds-and their neural correlates-were studied in women with provoked vestibulodynia (PVD; N = 15), a common subtype of vulvodynia (chronic vulvar pain), and p...

Positive affect and chronic pain: a preregistered systematic review and meta-analysis.

Feb 13, 2020

Chronic non-cancer pain (CNCP) is a significant health burden among adults. Standard behavioral therapies typically focus on targeting negative affect (NA) and yield only modest treatment effects. The...

Bodily changes and sensory sensitivity in complex regional pain syndrome and fibromyalgia.

Feb 13, 2020

Complex regional pain syndrome (CRPS) and fibromyalgia are chronic pain conditions of unexplained origins. In addition to symptoms in the diagnostic criteria, patients can report changes to vision and...

Long-term use of dienogest for the treatment of primary and secondary dysmenorrhea.

Feb 13, 2020

To investigate the safety and efficacy of dienogest (DNG), a progestational 19-norsteroid, administered for 52 weeks in patients with primary and secondary dysmenorrhea.A total of 147 patients with ...

Brain MRIs ID Racial Differences in Pain Response

Feb 11, 2020

TUESDAY, Feb. 11, 2020 (HealthDay News) -- Racial differences in pain may be rooted in life experience, rather than intrinsic biology, according to a study published online Feb. 3 in Nature Human Beha...

Opioid Crisis Along Mexico's Northern Border: Treatment Needs Mexican Opioid Crisis.

Feb 10, 2020

Heroin production for external markets and low rates of use in Mexico have had a long history. A recent shift toward an increase in use and related problems calls for the evaluation of treatment needs...

Opioid Prescribing Patterns of Oral and Maxillofacial Surgery Residents

Feb 10, 2020

The aim of this study was to report on the opioid prescribing patterns of oral and maxillofacial surgery residents for routine office-based procedures.A survey was sent to current resident members of ...

The impact of the abuse-deterrent reformulation of extended-release OxyContin on prescription pain reliever misuse and heroin initiation.

Feb 10, 2020

The introduction of abuse-deterrent OxyContin in 2010 was intended to reduce its misuse by making it more tamper resistant. However, some studies have suggested that this reformulation might have had ...

Nonpharmacological Adjunctive Treatment for Postpartum Women with Opioid Use Disorder

Feb 10, 2020

Over the past decade, opioid use disorder (OUD) among pregnant women has increased by over 400%. Although medication assisted treatment (MAT) provides necessary care for women with OUD, effective adju...

Early Age of Migraine Onset is Independently Related to Cognitive Decline and Symptoms of Anxiety Affect Quality of Life.

Feb 10, 2020

People with migraine experience cognitive decline more often than healthy controls, resulting in a significant functional impact. Early identifying influencing factors that contribute to cognitive dec...

The Profile and Prognosis of Youth With Status Migrainosus

Feb 10, 2020

To characterize the clinical features of a large sample of children, adolescents, and young adults with a history of status migrainosus (SM) and to describe their short-term prognosis.Data on the clin...

Longitudinal neuroimaging over 30 days: Temporal Characteristics of Migraine.

Feb 10, 2020

Although migraine is defined by the headache and headache associated symptoms, the true beginning of a migraine attack lies in the premonitory phase and to understand the generation of attacks one nee...

Exploring naturally occurring clinical subgroups of post-traumatic headache.

Feb 10, 2020

To explore naturally occurring clinical subgroups of post-traumatic headache.Persistent post-traumatic headache (PTH) is defined as a headache developing within 7 days of an injury that lasts for gr...

The prevalence of primary headache disorders in Saudi Arabia: a cross-sectional population-based study.

Feb 10, 2020

The large geographical gaps in our knowledge of the prevalence and burden of headache disorders include most of Eastern Mediterranean Region (EMR). Following a nationwide population-based study in Pak...

Fibromyalgia Symptom Severity and Psychosocial Outcomes in Fibromyalgia Patients with Hypovitaminosis D: A Prospective Questionnaire Study.

Feb 10, 2020

To evaluate the association between hypovitaminosis D and outcomes of symptom severity, mood disorders, fatigue, and quality of life in fibromyalgia (FM) patients.Five hundred ninety-three FM patients...

The mirogabalin ALDAY phase 3 program in pain associated with fibromyalgia: the lessons learned.

Feb 10, 2020

The main aim of this work was to identify and to share the lessons learned from the negative outcome of the mirogabalin ALDAY phase 3 clinical program in pain associated with fibromyalgia. These less...

Complex Regional Pain Syndrome Evolving to Full-Blown Fibromyalgia

Feb 10, 2020

Spread of complex regional pain syndrome (CRPS) outside the affected limb is a well-recognized phenomenon; nevertheless, the actual evolution from CRPS to fibromyalgia is poorly documented. Similar me...

Attitudes Towards and Management of Opioid-induced Hyperalgesia: A Survey of Chronic Pain Practitioners.

Feb 10, 2020

Opioid-induced hyperalgesia (OIH) is a phenomenon whereby opioids increase patients' pain sensitivity, complicating their use in analgesia. We explored practitioners' attitudes towards, and knowledge ...

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