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Pain General

A retrospective cohort study of cerebrovascular fibromuscular dysplasia.

Jan 16, 2023

Fibromuscular dysplasia (FMD) is a rare vasculopathy for which limited data are available particularly from Europe. Our aim was to study the clinical characteristics of a regional cohort of carotid fi...

Sleep and Sleep Complaints in Juvenile Fibromyalgia Syndrome.

Jan 16, 2023

To investigate sleep quality in juvenile fibromyalgia syndrome (JFS) and its impact on the global burden of the disease.Consecutive JFS patients who performed full-night polysomnography (PSG) were inc...

Comparative Safety Analysis of Opioid Agonist Treatment in Pregnant Women with Opioid Use Disorder: A Population-Based Study.

Jan 16, 2023

Receipt of opioid agonist treatment during early and late pregnancy for opioid use disorder may relate to varying perinatal risks. We aimed to assess the effect of time-varying prenatal exposure toÂ...

On-Site Therapeutic Drug Monitoring of Paracetamol Analgesic in Non-Invasively Collected Saliva for Personalized Medicine.

Jan 16, 2023

Paracetamol or acetaminophen is the main non-opioid analgesic recommended for mild pain by the World Health Organization (WHO) analgesic ladder. However, the high levels used of paracetamol are associ...

Uveitis in children: Epidemiological, clinical and prognostic characteristics.

Jan 16, 2023

The purpose of this study is to describe the characteristics and prognostic factors of pediatric uveitis in a French university referral hospital.We performed a retrospective study of all cases of all...

Nutritional status in rheumatoid arthritis.

Jan 16, 2023

Rheumatoid Arthritis (RA) is a chronic inflammatory autoimmune disease affecting the joints. It has been suggested that obesity increases the likelihood of RA development lowers the chance to achieve ...

Somatostatin Neurons from Periaqueductal Gray to Medulla Facilitate Neuropathic Pain in Male Mice.

Jan 16, 2023

Projections from the periaqueductal gray (PAG) to the rostral ventromedial medulla (RVM) are known to engage in descending pain modulation, but how the neural substrates of the PAG-RVM projections con...

Activation of protease-activated receptor-1 causes chronic pain in lupus-prone mice via suppressing spinal glial glutamate transporter function and enhancing glutamatergic synaptic activity.

Jan 16, 2023

Systemic lupus erythematosus (SLE) is an unpredictable autoimmune disease where the body's immune system mistakenly attacks healthy tissues in many parts of the body. Chronic pain is one of the most f...

Demographic trends associated with substance use disorder and risk for adverse obstetric outcomes with cannabis and opioid use disorders.

Jan 09, 2023

Substance use disorders (SUDs) are increasing in the obstetric population, vary with demographic characteristics, and are associated with adverse pregnancy outcomes. Cannabis use disorder and opioid u...

Aftereffects of alpha transcranial alternating current stimulation over the primary sensorimotor cortex on cortical processing of pain.

Jan 09, 2023

Transcranial alternating current stimulation (tACS) is believed to modulate brain oscillations in a frequency-specific manner. Given the correlation between sensorimotor α-oscillations and pain perce...

A double-blind phase II randomized controlled trial of an online cognitive bias modification for interpretation program with and without psychoeducation for people with chronic pain.

Jan 09, 2023

Cognitive bias modification for interpretation (CBM-I) is an effective intervention for anxiety, but there is only a single trial in people with chronic pain. The aim of this randomized controlled tri...

Lonp1 and Sig-1R contribute to the counteraction of ursolic acid against ochratoxin A-induced mitochondrial apoptosis.

Jan 02, 2023

Ochratoxin A (OTA), a secondary fungal metabolite with nephrotoxicity, is widespread in numerous kinds of feeds and foodstuffs. Ursolic acid (UA), a water-insoluble pentacyclic triterpene acid, exists...

Influence of constant rate infusions of fentanyl alone or in combination with lidocaine and ketamine on the response to surgery and postoperative pain in isoflurane anesthetized dogs undergoing unilateral mastectomy: a randomized clinical trial.

Jan 02, 2023

The aim of this study was to compare the effects of constant rate infusions (CRI) of fentanyl alone or combined with lidocaine and ketamine (FLK), on physiological parameters, isoflurane requirements ...

Long-term Evaluation of Spinal Cord Stimulation in Patients With Painful Diabetic Polyneuropathy: An Eight-to-Ten-Year Prospective Cohort Study.

Jan 02, 2023

This study aimed to evaluate the long-term effects of spinal cord stimulation (SCS) in patients with painful diabetic polyneuropathy (PDPN).This prospective cohort study was the eight-to-ten-year foll...

Effectiveness of Arthroscopically Assisted Surgery for Ankle Arthrodesis.

Jan 02, 2023

Regarding the treatment of ankle arthritis, the choice of arthroscopic ankle arthrodesis (AAA) or open ankle arthrodesis (OAA) remains controversial. To guide clinical decision-making, we conducted a ...

Sex dimorphism in Resolvin D5-induced analgesia in rat models of trigeminal pain.

Jan 02, 2023

Resolvin D5 (RvD5) is a specialized pro-resolving lipid mediator with potent anti-inflammatory and analgesic properties. Orofacial pain conditions, especially those that are chronic, present clinical ...

Na1.7 Channel Blocker [Ala, Phe, Leu, Arg]GpTx-1 Attenuates CFA-induced Inflammatory Hypersensitivity in Rats via Endogenous Enkephalin Mechanism.

Jan 02, 2023

Venom-derived Na1.7 channel blockers have promising prospects in pain management. The 34-residue tarantula peptide GpTx-1 is a potent Na1.7 channel blocker. Its powerful analog [Ala, Phe, Leu, Arg]GpT...

Veterans Affairs Bereaved Family Survey: Psychometric Evaluation

Dec 20, 2022

The following is a summary of "Psychometric Evaluation of the Veterans Affairs Bereaved Family Survey in Community Nursing Homes" published in the December 2022 issue of Pain and Symptom Management by...

COVID-19: Video and In-Person Palliative Care Delivery Challenges

Dec 20, 2022

The following is a summary of "Video and In-Person Palliative Care Delivery Challenges before and during the COVID-19 Pandemic" published in the December 2022 issue of Pain and Symptom Management by C...

Palliative Radiotherapy: Goals and Prognostic Understanding

Dec 20, 2022

The following is a summary of "Prognostic Understanding and Goals of Palliative Radiotherapy: A Qualitative Study" published in the December 2022 issue of Pain and Symptom Management by Chen et al. ...

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