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Pain General

The Association of Coronary Artery Calcium Score and Osteoporosis in Postmenopausal Women: A Cross-Sectional Study.

Dec 19, 2022

The association between osteoporosis, a common metabolic bone disorder, and atherosclerosis has been reported in different studies. In this study, we aimed to investigate the association between the c...

Gene selection by incorporating genetic networks into case-control association studies.

Dec 19, 2022

Large-scale genome-wide association studies (GWAS) have been successfully applied to a wide range of genetic variants underlying complex diseases. The network-based regression approach has been develo...

Predicting placebo analgesia in patients with chronic pain using natural language processing: a preliminary validation study.

Dec 19, 2022

Patients with chronic pain show large placebo effects in clinical trials, and inert pills can lead to clinically meaningful analgesia that can last from days to weeks. Whether the placebo response can...

Opioid dose and pain effects of an online pain self-management program to augment usual care in adults with chronic pain: a multisite randomized clinical trial.

Dec 19, 2022

Readily accessible nonpharmacological interventions that can assist in opioid dose reduction while managing pain is a priority for adults receiving long-term opioid therapy (LOT). Few large-scale eval...

All of Us Research Program: Unrelieved Symptom Predictors in Patients With Chronic Conditions

Dec 14, 2022

The following is a summary of "Predictors of Unrelieved Symptoms in All of Us Research Program Participants With Chronic Conditions" published in the December 2022 issue of Pain and Symptom Management...

Clinical Characteristics of Dysphagia in Solid Tumors Outside the Neck, Head, & Upper GI Tract

Dec 14, 2022

The following is a summary of "Dysphagia in Solid Tumors Outside the Head, Neck or Upper GI Tract: Clinical Characteristics" published in the December 2022 issue of Pain and Symptom Management by Kenn...

Patients with Ovarian Cancer: Race, Affordability and Utilization of Supportive Care

Dec 14, 2022

The following is a summary of "Race, Affordability and Utilization of Supportive Care in Ovarian Cancer Patients" published in the September 2022 issue of Pain and Symptom Management by Anyanwu et al....

The molecular associations in clathrin-coated pit regulate β-arrestin-mediated MAPK signaling downstream of μ-opioid receptor.

Dec 12, 2022

It has been thought that μ-opioid receptors (MOPs) activate the G protein-mediated analgesic pathway and β-arrestin 2-mediated side effect pathway; however, ligands that only minimally recruit β-ar...

Fibromyalgia Presents With A Straight Neck on Radiograph

Dec 09, 2022

Barring any other radiographic abnormalities, a straight neck may be a major anatomical aberration in fibromyalgia that has gone unnoticed. Robert Katz, MD, spoke with Physician’s Weekly abo...

Cancer Pain Treatment: Preferences of Patients for Rescue Medications

Dec 08, 2022

For a study, researchers sought to examine Chinese cancer patients' risk-benefit preferences for rescue medications (RD) and their willingness to pay (WTP) in the treatment of breakthrough cancer pain...

Severe Cancer Pain Treatment Using Intravenous Oxycodone Rapid Titration

Dec 08, 2022

For a study, researchers sought to evaluate the effectiveness of titrating the dosage of oxycodone intravenously in treating severe cancer pain. The second goal was the oral route's conversion ratio, ...

End-of-Life Family Caregivers: Experience with Symptom Management

Dec 08, 2022

About 30% of all fatalities in the US take place at home. Good end-of-life (EOL) care requires effective symptom management. In managing EOL symptom management, family caregivers are crucial. Accordin...

Identifying Factors Tied With Long-Term Opioid Therapy for SLE

Dec 07, 2022

Patients with SLE are more likely to receive opioid therapy not only due to SLE manifestations but also because of associated comorbidities. Patients with systemic lupus erythematosus (SLE) exp...

Adherence to coprescribing of laxatives with opioids and associated characteristics in general practices in the Netherlands.

Dec 05, 2022

Guidelines recommend to prescribe a laxative with an opioid to prevent constipation. We aimed to determine the adherence by general practitioners (GPs) to this recommendation and to explore which GP- ...

Adherence to coprescribing of laxatives with opioids and associated characteristics in general practices in the Netherlands.

Dec 05, 2022

Guidelines recommend to prescribe a laxative with an opioid to prevent constipation. We aimed to determine the adherence by general practitioners (GPs) to this recommendation and to explore which GP- ...

A digital application and augmented physician rounds reduce postoperative pain and opioid consumption after primary total knee replacement (TKR): a randomized clinical trial.

Dec 05, 2022

Severe postoperative pain not only is a considerable burden for patients but also leads to overprescription of opioids, resulting in considerable health concerns. The remarkable development of new tec...

A digital application and augmented physician rounds reduce postoperative pain and opioid consumption after primary total knee replacement (TKR): a randomized clinical trial.

Dec 05, 2022

Severe postoperative pain not only is a considerable burden for patients but also leads to overprescription of opioids, resulting in considerable health concerns. The remarkable development of new tec...

Regional versus general anesthesia in knee arthroplasty in patients with different classes of BMI: A matched analysis of the NSQIP database.

Dec 05, 2022

Knee arthroplasty for knee arthritis is a commonly performed surgery yielding excellent functional results and good pain relief. It is associated with post-surgical complications according to the type...

Regional versus general anesthesia in knee arthroplasty in patients with different classes of BMI: A matched analysis of the NSQIP database.

Dec 05, 2022

Knee arthroplasty for knee arthritis is a commonly performed surgery yielding excellent functional results and good pain relief. It is associated with post-surgical complications according to the type...

The effect of theta burst stimulation over the primary motor cortex on experimental hamstring pain: A randomised, controlled study.

Dec 05, 2022

Theta burst stimulation (TBS) over the primary motor cortex (M1) is an emerging technique that may have utility in the treatment of musculoskeletal pain. However, previous work exploring the analgesic...

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