Jun 27, 2022

Immune checkpoint inhibitors (ICI) are acclaimed for producing long-lasting anti-tumor responses, but they also generate immune-related adverse events (irAEs), which can range in severity and have an ...

Jun 27, 2022

Patients can improve the quality of their dying by preparing for the end of life and their impending death. For a study, researchers sought to determine the never-before-seen relationships between can...

Jun 27, 2022

Opioid misuse and opioid-related consequences, including fatalities, are extensively established in the United States. Opioid consumption, particularly fentanyl, has been growing throughout the Europe...

Jun 27, 2022

During the early COVID-19 epidemic, many hospice patients were physically segregated from family members and healthcare staff. Researchers sought to evaluate the lived experience of physical separatio...

Jun 16, 2022

Despite advances in antiretroviral treatment, people living with HIV infection (PLWH) in the United States continue to have a high symptom load. For a study, researchers sought to determine if the qua...

Jun 16, 2022

For a study, researchers sought to determine the link between palliative care (PC), patient-reported variables (quality of life and functional status), and outcomes. They conducted a prospective cohor...

May 31, 2022

For a study, researchers sought to enhance the conceptual and practical definitions of the term "self-management of cancer pain" in the concept analysis article by identifying associated antecedents, ...

May 31, 2022

For a study, researchers sought to see if intravenous patient-controlled analgesia (IVPCA) in a fast-track joint replacement program was linked to more perioperative opioid intake and a longer stay in...

May 31, 2022

For a study, researchers sought to determine how the presence of a parent affected the level of a child's suffering during invasive treatments. The systematic review began in July 2019 and was updated...

May 31, 2022

For a study, researchers sought to look into the perceptions and experiences of emergency department (ED) patients about pain and emergency care to help build future psychosocial interventions that ba...

May 31, 2022

Post-operative discomfort was one of the most serious issues faced by patients with coronary artery bypass graft surgery. For a study, researchers sought to determine how post-operative pain interfere...

May 31, 2022

Active psychosocial therapies for chronic postsurgical pain have shown promise. Preoperatively disturbed (elevated depressed symptoms, anxious symptoms, or pain catastrophizing) and non-distressed par...

May 16, 2022

Health education is one of the main items to enable the promotion of health for individuals with fibromyalgia (FM) in Primary Health Care (PHC) in Brazil. The purpose of this study was to validate a m...

May 16, 2022

This is a retrospective cohort study.This study aims to determine the proportional incidence, clinical characteristics, treatment patterns with complications and changes in treatment of vertebral frac...

May 16, 2022

Off-label (OL) drug use is the prescription of a drug for indications other than those authorised in its technical datasheet. The objective of this study was to identify drugs recommended in rheumatol...

May 16, 2022

Ankle distraction arthroplasty and supramalleolar osteotomy were both options for post-traumatic varus ankle arthritis (VAA), but their comparative effectiveness was scarcely reported. This study aime...

May 16, 2022

Neuroimaging is a powerful tool to investigate potential associations between chronic pain and brain structure. However, the proliferation of studies across diverse chronic pain syndromes and heteroge...

May 09, 2022

Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic trans...

May 09, 2022

Inflammatory arthritic diseases are characterized by a persistent inflammation of the synovial tissues where tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6) pro-inflammatory cytokines are...

May 09, 2022

Chronic pruritus is a prominent symptom of allergic contact dermatitis (ACD) and represent a huge unmet health problem. However, its underlying cellular and molecular mechanisms remain largely unexplo...