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Pain General

The Effect of Parental Presence on Pain Levels of Children During Invasive Procedures

May 31, 2022

For a study, researchers sought to determine how the presence of a parent affected the level of a child's suffering during invasive treatments. The systematic review began in July 2019 and was updated...

Patient Pain Experiences & the Emergency Department (ED) Encounter

May 31, 2022

For a study, researchers sought to look into the perceptions and experiences of emergency department (ED) patients about pain and emergency care to help build future psychosocial interventions that ba...

Pain Interference: Coronary Artery Bypass Graft (CABG) Surgery

May 31, 2022

Post-operative discomfort was one of the most serious issues faced by patients with coronary artery bypass graft surgery. For a study, researchers sought to determine how post-operative pain interfere...

The Impact of Preoperative Distress: PePS Intervention

May 31, 2022

Active psychosocial therapies for chronic postsurgical pain have shown promise. Preoperatively disturbed (elevated depressed symptoms, anxious symptoms, or pain catastrophizing) and non-distressed par...

(Fibro Friends): Validation of an Educational Program to Promote Health in Fibromyalgia.

May 16, 2022

Health education is one of the main items to enable the promotion of health for individuals with fibromyalgia (FM) in Primary Health Care (PHC) in Brazil. The purpose of this study was to validate a m...

Epidemiologic analysis of 8000 acute vertebral fractures: evolution of treatment and complications at 10-year follow-up.

May 16, 2022

This is a retrospective cohort study.This study aims to determine the proportional incidence, clinical characteristics, treatment patterns with complications and changes in treatment of vertebral frac...

Drugs Recommended in Adult Rheumatic Diseases, But Considered for Off-Label Use in Argentina.

May 16, 2022

Off-label (OL) drug use is the prescription of a drug for indications other than those authorised in its technical datasheet. The objective of this study was to identify drugs recommended in rheumatol...

Comparisons between ankle distraction arthroplasty and supramalleolar osteotomy for treatment of post-traumatic varus ankle osteoarthritis.

May 16, 2022

Ankle distraction arthroplasty and supramalleolar osteotomy were both options for post-traumatic varus ankle arthritis (VAA), but their comparative effectiveness was scarcely reported. This study aime...

Structural imaging studies of patients with chronic pain: an anatomic likelihood estimate meta-analysis.

May 16, 2022

Neuroimaging is a powerful tool to investigate potential associations between chronic pain and brain structure. However, the proliferation of studies across diverse chronic pain syndromes and heteroge...

LRP4 is required for the olfactory association task in the piriform cortex.

May 09, 2022

Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic trans...

Microfluidic-assisted electrospinning, an alternative to coaxial, as a controlled dual drug release system to treat inflammatory arthritic diseases.

May 09, 2022

Inflammatory arthritic diseases are characterized by a persistent inflammation of the synovial tissues where tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6) pro-inflammatory cytokines are...

Sensory neuron expressed TRPC3 mediates acute and chronic itch.

May 09, 2022

Chronic pruritus is a prominent symptom of allergic contact dermatitis (ACD) and represent a huge unmet health problem. However, its underlying cellular and molecular mechanisms remain largely unexplo...

A multicenter, randomized, double-blind, placebo-controlled, comparative study to evaluate the efficacy and safety of newly developed diclofenac patches in patients with cancer pain.

May 09, 2022

This phase III multicenter randomized double-blind placebo-controlled comparative study evaluated the efficacy and safety of diclofenac sodium patches for the treatment of cancer pain. The study consi...

Amygdalar functional connectivity during resting and evoked pain in youth with functional abdominal pain disorders.

May 02, 2022

Pediatric functional abdominal pain disorders (FAPD) are highly prevalent, difficult to diagnose, and challenging to treat. The brain systems supporting FAPD remain poorly understood. This investigati...

Preconditioning by voluntary wheel running attenuates later neuropathic pain via Nrf2 antioxidant signaling in rats.

May 02, 2022

Animal and human studies have shown that exercise prior to nerve injury prevents later chronic pain, but the mechanisms of such preconditioning remain elusive. Given that exercise acutely increases fo...

Short-Term & Long-Term Pain After Total Hip Arthroplasty (THA)

Apr 28, 2022

Elderly patients' rehabilitation was significantly affected by postoperative discomfort. There was a lack of understanding about how to help older adults return to daily living following discharge. Th...

Association of Hypertension With Knee Pain Severity Among Knee Osteoarthritis (OA) Patients

Apr 28, 2022

To evaluate the relationship between hypertension and knee discomfort severity in knee osteoarthritis (OA) patients. Cross-sectional analysis of OAI baseline data. Participants with knee OA (N=1,363) ...

Investigate Specialized Chronic Non-Cancer Pain Care among Emerging Adults

Apr 28, 2022

To learn more about the characteristics of young people who use a specialized chronic non-cancer pain clinic and the therapies they receive and utilize. Over a six-month period, a retrospective chart ...

Pain Interference With Daily Living Activities & Dependency Level of CABG Surgery Patients

Apr 28, 2022

One of the most serious issues people face in coronary bypass was postoperative pain. The severity of pain after surgery hinders general activity, sleep, deep breathing, and sleep quality. The descrip...

A Qualitative Analysis of the Perioperative Pain Self-Management (PePS) Intervention

Apr 28, 2022

Postoperatively distressed patients were more likely to develop chronic postsurgical pain. Psychological therapies, which are active, appear to be beneficial in reducing chronic postsurgical pain. The...

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