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Pain General

Investigate Specialized Chronic Non-Cancer Pain Care among Emerging Adults

Apr 28, 2022

To learn more about the characteristics of young people who use a specialized chronic non-cancer pain clinic and the therapies they receive and utilize. Over a six-month period, a retrospective chart ...

Pain Interference With Daily Living Activities & Dependency Level of CABG Surgery Patients

Apr 28, 2022

One of the most serious issues people face in coronary bypass was postoperative pain. The severity of pain after surgery hinders general activity, sleep, deep breathing, and sleep quality. The descrip...

A Qualitative Analysis of the Perioperative Pain Self-Management (PePS) Intervention

Apr 28, 2022

Postoperatively distressed patients were more likely to develop chronic postsurgical pain. Psychological therapies, which are active, appear to be beneficial in reducing chronic postsurgical pain. The...

Maternal and neonatal outcomes with the addition of intrathecal midazolam as an adjuvant to spinal anesthesia in cesarean delivery: A systematic review and meta-analysis of randomized controlled trials.

Apr 25, 2022

To determine the efficacy and safety, in terms of maternal and neonatal outcomes, of adding intrathecal midazolam to spinal anesthesia for cesarean delivery in healthy pregnant women.A meta-analysis o...

Re-thinking the definition of CPSP: composites of patient-reported pain-related outcomes versus pain intensities alone.

Apr 25, 2022

Chronic postsurgical pain (CPSP) is defined by pain intensity and pain-related functional interference. This study included measures of function in a composite score of patient-reported outcomes (PROs...

Targeting intrinsically disordered regions facilitates discovery of CaV3.2 inhibitory peptides for AAV-mediated peripheral analgesia.

Apr 18, 2022

Ample data support a prominent role of peripheral T-type calcium channels 3.2 (CaV3.2) in generating pain states. Development of primary sensory neuron-specific inhibitors of CaV3.2 channels is an opp...

Outcome measures in rheumatology applied in self-management interventions targeting people with inflammatory Arthritis A systematic review of outcome domains and measurement instruments.

Apr 11, 2022

Evaluating the effect of self-management interventions targeting people with inflammatory arthritis (IA) is a challenge because self-management interventions are complex and consensus on important out...

Altered pain sensitivity in 5×FAD mice is associated with the dendritic spine loss in ACC pyramidal neurons.

Apr 11, 2022

Chronic pain is highly prevalent. Individuals with cognitive disorders such as Alzheimer's disease are susceptible population in which pain is frequently difficult to diagnosis. It is still unclear wh...

Autobiographical memory predicts postsurgical pain up to 12 months after major surgery.

Apr 11, 2022

Recent cross-sectional studies have identified differences in autobiographical memory (AM) among individuals with chronic pain, but temporal relationship between the two is unknown. Moreover, AM has y...

Relationship between spinal reflexes and leg motor function in sub-acute and chronic stroke patients.

Apr 04, 2022

To assess the relationship between spinal reflexes and motor function in sub-acute (SAS) and chronic stroke (CS) patients.Twelve SAS and 16 CS patients underwent electrophysiological assessment of het...

Transient receptor potential melastatin 8 (TRPM8) is required for nitroglycerin and calcitonin gene-related peptide induced migraine-like pain behaviors in mice.

Apr 04, 2022

Migraine is a complex neurovascular disorder that is one of the leading causes of disability and a reduced quality of life. Even with such a high societal impact, our understanding of the cellular and...

A systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease associated persistent pain.

Apr 04, 2022

Burrowing behaviour is employed to assess pain-associated behaviour in laboratory rodents. To gain insight in how models of disease associated persistent pain and analgesics affect burrowing behaviour...

Take-Home OAT During Pandemic Lowered Treatment Interruption

Mar 28, 2022

For a study, researchers sought to determine if higher opioid agonist therapy (OAT) take-home dosages early in the COVID-19 epidemic were related to treatment retention and opioid-related harm. A retr...

Evaluation of diagnostic and treatment approaches to acute dyspnea in a palliative care setting among medical doctors with different educational levels.

Mar 28, 2022

Dyspnea is common in patients with advanced cancer. Diagnostic procedures in patients with dyspnea are mandatory but often time-consuming and hamper rapid treatment of the underlying refractory sympto...

The relationship of hip loading asymmetry and radiological parameters of the spine in Lenke type 1 idiopathic scoliosis.

Mar 28, 2022

Idiopathic scoliosis does not only cause structural changes in the spine, but also functional changes of the musculoskeletal system.Does idiopathic scoliosis lead to asymmetric hip loading in severe L...

Epaxial muscle atrophy is more evident in large dogs with intervertebral disc disease than in dogs with ischaemic myelopathy.

Mar 28, 2022

Cross-sectional area (CSA) decreases and fat infiltration increases in epaxial muscles of Dachshunds with intervertebral disc disease (IVDD), but less is known about large breed dogs with IVDD. The ai...

Association between chronic low back pain and regional brain atrophy in a Japanese older population: the Hisayama Study.

Mar 28, 2022

Chronic low back pain (CLBP) is the leading cause of years lived with disability. Recently, it has been reported that CLBP is associated with alterations in the central nervous system. The present stu...

Facet joint disease in patients with axial spondyloarthritis: A retrospective computed tomography study.

Mar 21, 2022

Facet joints' (FJ) ankylosis was reported in patients with radiographic axial spondyloarthritis (r-AxSpA). However, a detailed FJ evaluation over the whole spectrum of AxSpA was not performed. We aime...

Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis.

Mar 21, 2022

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder. Separate lines of evidence suggest that synapses and astrocytes play a role in the pathological mechanisms underlying ALS. Gi...

Hospitalizations Associated With Rheumatic Disease in Alaska, 2015-2018.

Mar 21, 2022

Few studies have evaluated hospitalizations associated with rheumatic disease in Indigenous North American populations. The objective of this study was to determine the characteristics of people hospi...

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