Apr 25, 2022

To determine the efficacy and safety, in terms of maternal and neonatal outcomes, of adding intrathecal midazolam to spinal anesthesia for cesarean delivery in healthy pregnant women.A meta-analysis o...

Apr 25, 2022

Chronic postsurgical pain (CPSP) is defined by pain intensity and pain-related functional interference. This study included measures of function in a composite score of patient-reported outcomes (PROs...

Apr 18, 2022

Ample data support a prominent role of peripheral T-type calcium channels 3.2 (CaV3.2) in generating pain states. Development of primary sensory neuron-specific inhibitors of CaV3.2 channels is an opp...

Apr 11, 2022

Evaluating the effect of self-management interventions targeting people with inflammatory arthritis (IA) is a challenge because self-management interventions are complex and consensus on important out...

Apr 11, 2022

Chronic pain is highly prevalent. Individuals with cognitive disorders such as Alzheimer's disease are susceptible population in which pain is frequently difficult to diagnosis. It is still unclear wh...

Apr 11, 2022

Recent cross-sectional studies have identified differences in autobiographical memory (AM) among individuals with chronic pain, but temporal relationship between the two is unknown. Moreover, AM has y...

Apr 04, 2022

To assess the relationship between spinal reflexes and motor function in sub-acute (SAS) and chronic stroke (CS) patients.Twelve SAS and 16 CS patients underwent electrophysiological assessment of het...

Apr 04, 2022

Migraine is a complex neurovascular disorder that is one of the leading causes of disability and a reduced quality of life. Even with such a high societal impact, our understanding of the cellular and...

Apr 04, 2022

Burrowing behaviour is employed to assess pain-associated behaviour in laboratory rodents. To gain insight in how models of disease associated persistent pain and analgesics affect burrowing behaviour...

Mar 28, 2022

For a study, researchers sought to determine if higher opioid agonist therapy (OAT) take-home dosages early in the COVID-19 epidemic were related to treatment retention and opioid-related harm. A retr...

Mar 28, 2022

Dyspnea is common in patients with advanced cancer. Diagnostic procedures in patients with dyspnea are mandatory but often time-consuming and hamper rapid treatment of the underlying refractory sympto...

Mar 28, 2022

Idiopathic scoliosis does not only cause structural changes in the spine, but also functional changes of the musculoskeletal system.Does idiopathic scoliosis lead to asymmetric hip loading in severe L...

Mar 28, 2022

Cross-sectional area (CSA) decreases and fat infiltration increases in epaxial muscles of Dachshunds with intervertebral disc disease (IVDD), but less is known about large breed dogs with IVDD. The ai...

Mar 28, 2022

Chronic low back pain (CLBP) is the leading cause of years lived with disability. Recently, it has been reported that CLBP is associated with alterations in the central nervous system. The present stu...

Mar 21, 2022

Facet joints' (FJ) ankylosis was reported in patients with radiographic axial spondyloarthritis (r-AxSpA). However, a detailed FJ evaluation over the whole spectrum of AxSpA was not performed. We aime...

Mar 21, 2022

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder. Separate lines of evidence suggest that synapses and astrocytes play a role in the pathological mechanisms underlying ALS. Gi...

Mar 21, 2022

Few studies have evaluated hospitalizations associated with rheumatic disease in Indigenous North American populations. The objective of this study was to determine the characteristics of people hospi...

Mar 21, 2022

Poststroke pain (PSP) is a heterogeneous term encompassing both central neuropathic (ie, central poststroke pain [CPSP]) and nonneuropathic poststroke pain (CNNP) syndromes. Central poststroke pain is...

Mar 14, 2022

"Lock-in" programs are used by health insurers to reduce the risk of adverse outcomes that can result from overutilization of opioids and other controlled substances. We estimated the association betw...

Mar 14, 2022

Enhanced Recovery After Surgery (ERAS) has become the standard of care in microsurgical breast reconstruction. The current literature provides overwhelming evidence of the benefit of ERAS pathways in ...