Nov 29, 2021

The roots of Kadsura coccinea is commonly used in Tujia ethnomedicine, named "heilaohu", having the effect of treating rheumatic arthritis (RA). Chemical investigation on the ethanol extract of heilao...

Nov 29, 2021

Nociceptors are known to directly recognize bacterial cell wall components or secreted toxins, thereby leading to pain induced by bacterial infection. However, direct activation of nociceptors by bact...

Nov 29, 2021

Prior systematic reviews have summarized the prevalence and impact of chronic pain in "average" pediatric (i.e., school-age) and adult (i.e., middle-age) age groups. To our knowledge, this is the firs...

Nov 22, 2021

High-level spinal cord injury commonly leads to blood pressure instability. This manifests clinically as orthostatic hypotension (OH), where blood pressure can drop to the point of loss of consciousne...

Nov 22, 2021

Psoriasis is a dermatological condition often associated with systemic comorbidities such as arthritis. Because of the vital role of treatment compliance in improvement in patients' condition and the ...

Nov 22, 2021

There is moderate quality evidence that exercise can help prevent future low back pain (LBP). This study aimed to explore patient needs and preferences for exercise programs to prevent LBP, and the ou...

Nov 22, 2021

This study describes the minimum incidence of pediatric complex regional pain syndrome (CRPS), clinical features, and treatments recommended by pediatricians and pain clinics in Canada. Participants i...

Nov 15, 2021

To analyze the development of upper airway in children with different characteristics. From June 2018 to June 2020, a total of 425 children younger than 16 years old who underwent head MRI examinati...

Nov 08, 2021

Parental substance misuse impacts millions of children globally and is a major determinant of repeat maltreatment and out-of-home placement. There is little published research on family-based, compreh...

Nov 08, 2021

Pain is a common and debilitating symptom of inflammatory bowel disease (IBD). Based on evidence that peripheral GABAA receptor (GAR) inhibition plays an important role in establishing colonic afferen...

Nov 08, 2021

A number of studies have demonstrated substantial individual differences in placebo effects. We aimed to identify individual psychological factors that potentially predicted the magnitude of placebo h...

Nov 01, 2021

Alpha oscillatory activity (8-13 Hz) is the dominant rhythm in the awake brain and is known to play an important role in pain states. Previous studies have identified alpha band slowing and increased ...

Nov 01, 2021

IMT504, a noncoding, non-CpG oligodeoxynucleotide, modulates pain-like behavior in rats undergoing peripheral nerve injury, through mechanisms that remain poorly characterized. Here, we chose the spar...

Oct 25, 2021

Oral health related quality of life (OHRQoL) is known to be reduced in disadvantaged populations, including people who inject drugs. Mental health issues, such as depression are also commonly reported...

Oct 25, 2021

Although tramadol is increasingly used to manage chronic noncancer pain, few safety studies have compared it with other opioids.To assess the associations of tramadol, compared with codeine, with mort...

Oct 25, 2021

There is a need to better understand biological factors that increase the risk of persistent musculoskeletal pain and heightened pain sensitivity. Knowing the heritability (how genes account for diffe...

Oct 18, 2021

To analyze neuroendocrine neoplasm (NEN) bone metastasis (BM) and Gallium-68 (68Ga)-DOTA-TATE performance and to explore their correlation with the immunohistochemical proliferation index (Ki-67).A to...

Oct 18, 2021

Patients with Rheumatoid Arthritis (RA) often report impaired health-related quality of life (HrQoL) such as difficulties in daily life, pain, fatigue and an affected social life. Even when lowering d...

Oct 18, 2021

Postmenopausal vaginal symptoms are common and frequently detrimental to a woman's quality of life. Fractional carbon dioxide vaginal laser is increasingly offered as a treatment, but the efficacy rem...

Oct 11, 2021

There is interest in the potential of internet-delivered programs to cost-effectively increase access to pain management for people with chronic pain. However, few large-scale clinical and economic ev...