Pain General
Aug 12, 2021
“For most patients, pain control remains unsatisfactory,” explains Feng Pan, PhD, MMed, MBBS. “The few pharmacologic analgesic options available have limited efficacy and carry a substantial ris...
Aug 12, 2021
Long-term potentiation (LTP) of synaptic transmission is considered to be a cellular counterpart of learning and memory. Activation of postsynaptic NMDA type glutamate receptor (NMDA-R) induces traffi...
Aug 12, 2021
Spinal cord injury (SCI), as one of the intractable diseases in clinical medicine, is afflicting thousands of human beings, and the pathological changes after the injury have been a hot spot for explo...
Aug 12, 2021
Endogenous pain modulation, as tested by the conditioned pain modulation (CPM) protocol, is typically less efficient in chronic pain patients compared to healthy controls. We aimed to assess whether C...
Aug 09, 2021
“Discrimination negatively influences health and well-being in the general population, but its impact on people with pain is unclear,” explains Ruth A. Hackett, PhD. “Therefore, it is important ...
Aug 09, 2021
Herbal beverages have been used as a natural part of the medicinal and food culture in northwestern Argentina. The flower beverages (infusion or decoction) of Acacia caven, Geoffroea decorticans and L...
Aug 09, 2021
Chronic spinal pain poses complex challenges for healthcare around the world and is in need of effective interventions. Pain Neuroscience Education (PNE) is a promising intervention hypothesized to im...
Aug 08, 2021
“Migraine, which affects more than 1 billion people worldwide, is one of the leading causes of disability in people younger than 50,” says Keisuke Suzuki, MD, PhD. “In addition to moderate-to-se...
Aug 05, 2021
Men with Peyronie’s disease (PD) typically present with complaints of penile deformity, but some patients also report suffering from pain and erectile dysfunction (ED). “There is a common misconc...
Aug 05, 2021
We aimed to identify differences in prescription opioid-related behaviors between adults with and without disabilities in the U.S. We analyzed data from the 2015-2017 National Survey on Drug Use and H...
Aug 05, 2021
Primary headache is a common cause of pediatric emergency department (PED) visits. Without published guidelines to direct treatment options, various strategies lacking evidence are often employed. Thi...
Aug 05, 2021
To explore the effectiveness and safety of 3 oral cannabinoid preparations (FM2®, Bedrocan® and Bediol®) in the treatment of chronic migraine.Retrospective, cohort study.Patients with chronic migra...
Aug 05, 2021
The delta value of oxyhemoglobin (Δ-HbO) determined by functional near-infrared spectroscopy at prefrontal cortex (PFC) and motor cortex (MC) based on primary (25 °C) and secondary (5 °C) thermal...
Aug 05, 2021
Various studies have shown that overweight and obesity are central features of FM, but the real impact of a high BMI on clinical severity in patients with FM is still controversial. The aim of this st...
Aug 05, 2021
In clinical practice, the bodily distribution of chronic pain is often used in conjunction with other signs and symptoms to support a diagnosis or treatment plan. For example, the diagnosis of fibromy...
Aug 05, 2021
Depression is highly prevalent among hospitalized patients with pneumonia. At discharge, these patients transfer to a less care-intensive home-based setting. Nevertheless, little is known on the progn...
Aug 05, 2021
Evaluation of the diagnostic accuracy of a checklist-style structured reporting template in the setting of whole-body multislice computed tomography in major trauma patients depending on the level ...
Aug 05, 2021
B cells can become activated in germinal center (GC) reactions in secondary lymphoid tissue and ectopic GCs in synovium in RA that may be TNF and lymphotoxin (LT) dependent. Here we characterized the ...
Aug 05, 2021
Several health research agendas have successfully been developed with adults but rarely with children. Children are still seldom recognized as possessing credible knowledge about their own body and li...
Aug 05, 2021
Lower back pain (LBP) is a prevalent and challenging condition in primary care. The effectiveness of an individually tailored self-management support tool delivered via a smartphone app has not been r...