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Pain General

Substance use and suicide outcomes among self-injured trauma patients.

Jul 29, 2021

Research indicates alcohol (AUD) or substance (SUD) use disorders and acute alcohol or drug use serve as risk factors for suicidal behaviors and death both distally and proximally to a suicidal event....

Ultra-Low Energy Cycled Burst Spinal Cord Stimulation Yields Robust Outcomes in Pain, Function, and Affective Domains: A Subanalysis From Two Prospective, Multicenter, International Clinical Trials.

Jul 29, 2021

DeRidder's burst stimulation design has become a key spinal cord stimulation (SCS) waveform because it reduces the intensity of pain as well as its associated emotional distress. The brain pathways un...

Adolescent pain, anxiety, and depressive problems: a twin study of their co-occurrence and the relationship to substance use.

Jul 29, 2021

Data on the etiological factors underlying the co-occurrence of common adolescent pain with anxiety and depression symptoms are very limited. Opioid prescriptions for adolescent pain problems are on t...

Association between bariatric surgery with long-term analgesic prescription and all-cause mortality among patients with osteoarthritis: a general population-based cohort study.

Jul 26, 2021

There is still a large unmet need for novel osteoarthritis (OA) treatments that could provide clinically important effects on long-term pain relief (≥12 months). We examined the relation of bariatri...

Evaluation of the HeroWear Apex back-assist exosuit during multiple brief tasks.

Jul 26, 2021

Trunk exoskeletons are wearable devices that support humans during physically demanding tasks by reducing biomechanical loads on the back. While most trunk exoskeletons are rigid devices, more lightwe...

Endovascular treatment of a ruptured post-traumatic false aneurysm of the aortic isthmus: A case report.

Jul 26, 2021

The false aneurysm of the aortic isthmus is, given its severity and case fatality rate, a subject of interest in vascular surgery. The interest of this article is the analysis of the different charact...

Piezo2 mechanosensitive ion channel is located to sensory neurons and nonneuronal cells in rat peripheral sensory pathway: implications in pain.

Jul 26, 2021

Piezo2 mechanotransduction channel is a crucial mediator of sensory neurons for sensing and transducing touch, vibration, and proprioception. We here characterized Piezo2 expression and cell specifici...

Postinjury stimulation triggers a transition to nociplastic pain in mice.

Jul 26, 2021

Acute injury-induced pain can transition to chronic nociplastic pain, which predominantly affects women. To facilitate studies on the underlying mechanisms of nociplastic pain, we developed a mouse mo...

Clinical relevance of attentional biases in pediatric chronic pain: an eye-tracking study.

Jul 26, 2021

Attentional biases have been posited as one of the key mechanisms underlying the development and maintenance of chronic pain and co-occurring internalizing mental health symptoms. Despite this theoret...

Musculoskeletal ultrasonography in rheumatic diseases.

Jul 22, 2021

Ultrasonography is an imaging technique that is used for evaluation of soft tissues based-on utilization of sound waves. Sound waves has been used for a long time in non-medical field including milita...

Frailty as a novel predictor of achieving comprehensive disease control (CDC) in rheumatoid arthritis.

Jul 22, 2021

Frailty is a construct recently introduced in the context of inflammatory joint diseases. To date, it is not clear if frailty can act as a negative factor in the achievement of comprehensive disease c...

Impact of various MRI signal intensity changes on radiological parameters, the neurological status, and surgical outcomes in degenerative cervical myelopathy.

Jul 19, 2021

A retrospective study of prospectively collected date.The present study aimed to identify patient characteristics, radiological factors, the neurological status, and postoperative outcomes associated ...

Impaired Antibody Response to the BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccine in Patients With Systemic Lupus Erythematosus and Rheumatoid Arthritis.

Jul 19, 2021

With a vaccine effectiveness of 95% for preventing coronavirus disease 2019 (COVID-19), Pfizer-BioNTech BNT162b2 (BNT162b2) was the first vaccine against severe acute respiratory syndrome coronavirus ...

Diagnostic accuracy of the PEG scale, a three-item questionnaire for grading the impact of orofacial pain-related dysfunction.

Jul 19, 2021

Purpose of this study was to examine the discriminative properties of the three-item PEG questionnaire for grading impact of non-dental orofacial pain.286 consecutive patients with orofacial pain of n...

Evaluating the stability of opioid efficacy over 12 months in patients with chronic noncancer pain who initially demonstrate benefit from extended release oxycodone or hydrocodone: harmonization of Food and Drug Administration patient-level drug safety study data.

Jul 19, 2021

Opioids relieve acute pain, but there is little evidence to support the stability of the benefit over long-term treatment of chronic noncancer pain. Previous systematic reviews consider only group lev...

Using wearable technology to detect prescription opioid self-administration.

Jul 19, 2021

Appropriate monitoring of opioid use in patients with pain conditions is paramount, yet it remains a very challenging task. The current work examined the use of a wearable sensor to detect self-admini...

Longitudinal effects of adverse childhood experiences on substance use transition patterns during young adulthood.

Jul 12, 2021

Few studies have investigated how adverse childhood experiences are associated with substance use patterns during young adulthood, a crucial developmental period.The objective of this study was to ext...

Distinct patterns of MRI lesions in MOG antibody disease and AQP4 NMOSD: a systematic review and meta-analysis.

Jul 12, 2021

the distinct MRI features of MOG-antibody disease (MOG-AD) and AQP4-NMOSD are still poorly defined. We performed a systematic review and meta-analysis to identify specific patterns of MRI abnormalitie...

Impact of Cadmium Mediated by Tobacco Use in Musculoskeletal Diseases.

Jul 12, 2021

Tobacco use has a negative impact on health due to its relationship with the development of high-mortality diseases, such as pulmonary cancer. However, the effect of cadmium (Cd), present in tobacco s...

TAK1 in the AP-1 pathway is a critical target of Saururus chinensis (Lour.) Baill in its anti-inflammatory action.

Jul 12, 2021

Saururus chinensis (Lour.) Baill (Saururaceae), also known as Asian lizard's tail, is a plant commonly found in East Asia. Its leaves have been used in traditional medicine to treat many diseases such...

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