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Pain General

Cost-effectiveness analysis of branded and authorized generic celecoxib for patients with chronic pain in Japan.

Jul 08, 2021

The aim of this study was to examine the cost-effectiveness of branded and authorized generic (AG) celecoxib for chronic pain patients with osteoarthritis (OA), rheumatoid arthritis (RA), and low back...

Voluntary exercise blocks ongoing pain and diminishes bone remodeling while sparing protective mechanical pain in a rat model of advanced osteoarthritis pain.

Jul 08, 2021

Exercise is the most common treatment recommended by health care providers for treatment of musculoskeletal pain. We examined whether voluntary running wheel exercise improves pain and bone remodeling...

Pain is common after sexual assault and posttraumatic arousal/reactivity symptoms mediate the development of new or worsening persistent pain.

Jul 08, 2021

Clinically significant new or worsening pain (CSNWP) is a common, yet often overlooked, sequelae of sexual assault. Little is known regarding factors influencing the development of CSNWP in sexual ass...

Self-selection of gestational lumbopelvic posture and bipedal evolution.

Jul 05, 2021

Not all pregnant women seem to select the more curved lumbopelvic posture that their sexual dimorphic anatomy allows even though many previous researchers have assumed lumbopelvic curvature to be stan...

The effect of short-term spinal cord electrical stimulation on patients with postherpetic neuralgia and its effect on sleep quality.

Jul 05, 2021

To investigate the effect of short-term spinal cord electrical stimulation (stSCS) on postherpetic neuralgia (PHN) and its effect on sleep quality in patients in Guangxi, China.160 patients with acute...

Current Epidemiology and Risk Factors for the Development of Hand Osteoarthritis.

Jul 05, 2021

Hand osteoarthritis (hand OA), the most common peripheral arthritis in the world, is less studied than osteoarthritis (OA) of the knee and hip. However, it is uniquely situated to offer novel insight ...

A novel small-bodied rupicolous Cnemaspis Strauch, 1887 (Squamata: Gekkonidae) from the northern Western Ghats, Maharashtra, India, with comments on the status of C. indraneildasii, Bauer 2000.

Jul 01, 2021

We describe a distinct new rupicolous Cnemaspis based on four adult specimens collected from the Kedareshwar caves on Harishchandragad mountain, from the northern Western Ghats, approximately 1200 m a...

The impact of chronic pain on driving behaviour: a systematic review.

Jul 01, 2021

Driving is a complex task that requires both the ability to rapidly identify potential hazards and to respond appropriately to driving situations to avoid crashing. A great deal of research has sought...

Neuronal basis for pain- and anxiety-like behaviors in the central nucleus of the amygdala.

Jul 01, 2021

Chronic pain is often accompanied by anxiety and depression disorders. Amygdala nuclei play important roles in emotional responses, fear, depression, anxiety and pain modulation. The exact mechanism o...

Developing consensus on core outcome domains for assessing effectiveness in perioperative pain management: results of the PROMPT/IMI-PainCare Delphi Meeting.

Jul 01, 2021

Postoperative pain management is still insufficient, leading to major deficits, including patient suffering, impaired surgical recovery, long-term opioid intake, and post-surgical chronic pain. Yet, i...

Cedrus deodara (Roxb. ex D.Don) G.Don: A review of traditional use, phytochemical composition and pharmacology.

Jun 28, 2021

Cedrus deodara (Roxb. ex D.Don) G.Don (Family: Pinaceae) is a medicinal tree traditionally important and well mentioned in traditional system of medicine of India, Pakistan, China, Korea etc. for its ...

Lysophosphatidic acid activates nociceptors and causes pain or itch depending on the application mode in human skin.

Jun 28, 2021

Lysophosphatidic acid (LPA) is involved in the pathophysiology of cholestatic pruritus and neuropathic pain. Slowly conducting peripheral afferent C-nerve fibers are crucial in the sensations of itch ...

Effects of combined THC and heroin vapor inhalation in rats.

Jun 24, 2021

Opioids are effective medications, but they have several key limitations including the development of tolerance, establishment of dependence, diversion for non-medical use, and the development of addi...

Exploring how hospitalization can alter hepatitis c virus treatment prioritization and trajectories in people who use drugs: A qualitative analysis.

Jun 24, 2021

People who use drugs (PWUD) have high rates of hepatitis C virus (HCV) infection. Hospitalization can be a time for PWUD to engage in addiction treatment, but little is known about how hospitalization...

Primary headaches during the COVID-19 lockdown in Germany: analysis of data from 2325 patients using an electronic headache diary.

Jun 24, 2021

Lockdown measures due to the COVID-19 pandemic have led to lifestyle changes, which in turn may have an impact on the course of headache disorders. We aimed to assess changes in primary headache chara...

Is psychiatric morbidity in chronic migraine associated with poor outcome: Experience from a tertiary care centrer.

Jun 24, 2021

Chronic Migraine is defined as headache occurring on 15 or more days/month for more than 3 months, which, on at least 8 days/month, has the features of migraine headache. This constitutes 10%-15% of a...

The American Headache Society Consensus Statement: Update on integrating new migraine treatments into clinical practice.

Jun 24, 2021

To incorporate recent research findings, expert consensus, and patient perspectives into updated guidance on the use of new acute and preventive treatments for migraine in adults.The American Headache...

A family-based study to identify genetic biomarkers of fibromyalgia: consideration of patients' subgroups.

Jun 24, 2021

Evidence from genome-wide and candidate gene association studies, familial aggregation and linkage analyses demonstrate the genetic contribution to fibromyalgia (FM) disease. This study aimed to ident...

Mental health and well-being during the COVID-19 pandemic: stress vulnerability, resilience and mood disturbances in fibromyalgia and rheumatoid arthritis.

Jun 24, 2021

The COVID-19 pandemic severely increased the stress levels in the population. The aim of present study was to investigate the impact of the lockdown measures on emotional well-being and disease activi...

Dietary habits in patients with fibromyalgia: a cross-sectional study.

Jun 24, 2021

To the scarce information on dietary habits in fibromyalgia (FM), it is added that there are no comparative studies with other rheumatic diseases. The objective of this study was to characterise the d...

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