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Pain General

Predictors of Improvement in Pediatric Chronic Migraine: Results from the Cognitive-Behavioral Therapy and Amitriptyline Trial.

May 27, 2021

Explore predictors of improvement in headache days and migraine-related disability through a secondary analysis of the cognitive-behavioral therapy plus amitriptyline trial in children and adolescents...

Burden of migraine and unmet needs from the patients' perspective: a survey across 11 specialized headache clinics in Korea.

May 27, 2021

Migraine is a neurological, primary headache disorder affecting more than 1 billion people worldwide, with a multi-faceted burden that can significantly impact the everyday life of a patient, both dur...

InterMiG: international differences in the therapeutic approach to migraine patients in specialized headache centers.

May 27, 2021

There is currently a wide therapeutic arsenal for migraine patients, without a single first-line preventive drug and we choose the different available alternatives taking into account comorbidities, n...

Sarcopenia Is Associated With Increased Risks of Rotator Cuff Tendon Diseases Among Community-Dwelling Elders: A Cross-Sectional Quantitative Ultrasound Study.

May 27, 2021

Recently, the association between sarcopenia and various musculoskeletal disorders, such as lumbar spine stenosis and fibromyalgia, has been highlighted. However, the relationship between sarcopenia ...

Visit-to-visit blood pressure variability and regional cerebral perfusion decline in older adults.

May 27, 2021

Blood pressure variability (BPV) is linked to dementia risk, possibly through cerebral hypoperfusion. We investigated BPV over 1 year and concurrent regional cerebral perfusion decline in older adults...

Talking about post-injury sexual functioning: The views of people with spinal cord injuries-A qualitative interview study.

May 27, 2021

This study aimed to explore perceptions of people with spinal cord injuries regarding the information they received during their rehabilitation programme on post-injury sexual functioning.Spinal cord ...

Peritraumatic 17β-estradiol levels influence chronic posttraumatic pain outcomes.

May 27, 2021

Biologic factors that predict risk for and mediate the development of common outcomes of trauma exposure such as chronic posttraumatic pain (CPTP) are poorly understood. In the current study, we exami...

Central Sensitization Inventory in endometriosis.

May 27, 2021

A key clinical problem is identifying the endometriosis patient whose pain is complicated by central nervous system sensitization, where conventional gynecologic treatment (e.g. hormonal therapy or su...

Deficit of β-endorphin neurons in the hypothalamus and high expression of MOR in mesolimbic structures are related to high alcohol consumption in outbred rats.

May 24, 2021

Clinical studies have postulated that β-endorphin deficiency generates excessive alcohol consumption and, it has been shown that the reduction of β-endorphin neurons increases alcohol intake in anim...

Impact of COVID-19 on chronic migraine treated with erenumab: a case report.

May 24, 2021

Headache is a frequent symptom of the novel coronavirus 19 disease (COVID-19). To date, there are limited information on how COVID-19 affects migraine and its treatment.A 47-year-old patient, sufferin...

Patient experience of telemedicine for headache care during the COVID-19 pandemic: An American Migraine Foundation survey study.

May 24, 2021

We sought to investigate the patient experience of telemedicine for headache care during the coronavirus disease 2019 (COVID-19) pandemic.The use of telemedicine has rapidly expanded and evolved since...

The effect of COVID19 public health restrictions on the health of people with musculoskeletal conditions and symptoms: the CONTAIN study.

May 24, 2021

To quantify the change in quality of life, disease-specific indicators, health, and lifestyle before and during the COVID19 pandemic amongst people with musculoskeletal diagnoses and symptoms.We under...

Clinical Features and Treatment Response in Immune-Mediated Small Fiber Neuropathy with Trisulfated Heparin Disaccharide or Fibroblast Growth Factor Receptor 3 Antibodies.

May 24, 2021

Novel antibodies to trisulfated heparin disaccharide (TS-HDS) and fibroblast growth factor receptor 3 (FGFR-3) have been recently described in otherwise cryptogenic small fiber neuropathy (SFN) cases....

A novel computational technique for the quantification of temporal summation in healthy individuals.

May 24, 2021

The pathophysiology of chronic musculoskeletal pain is linked to the neurophysiologic condition known as central sensitization. Developing reliable, sensitive and clinically feasible techniques for qu...

Changes in secondary outcomes associated with brief interventions for problem gambling in methadone patients.

May 24, 2021

Patients in methadone maintenance treatment (MMT) with problem gambling (PG) experience worse psychosocial outcomes than their non-PG counterparts. Interventions targeting PG in MMT may enhance psycho...

Recombinant CD300c-Fc fusion protein attenuates collagen-induced arthritis in mice.

May 24, 2021

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation and tissue destruction. Immune responses mediated by T cells and autoantibodies are known to play critical...

Comparison of the AAPT Fibromyalgia Diagnostic Criteria and Modified FAS Criteria with Existing ACR Criteria for Fibromyalgia in Korean Patients.

May 24, 2021

Recently, new sets of diagnostic criteria were proposed, including criteria by the ACTTION-American Pain Society Pain Taxonomy (AAPT) group and Fibromyalgia Assessment Status (FAS) 2019 modified crite...

The beneficial effect of positive treatment expectations on pharmacological migraine prophylaxis.

May 24, 2021

Migraine is one of the leading causes of years lived with disability and considered to be a major global health concern. Pharmacological preventive treatment often causes side effects that limit the a...

Public support for harm reduction: A population survey of Canadian adults.

May 20, 2021

We described public views toward harm reduction among Canadian adults and tested a social exposure model predicting support for these contentious services, drawing on theories in the morality policy, ...

Distress tolerance and subsequent substance use throughout high school.

May 20, 2021

To examine the association of perceived distress tolerance-one's ability to endure aversive experiences-with subsequent substance use frequency during adolescence.High school students (N = 3,203) we...

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