Dec 10, 2020

The prevalence of poisoning from methadone and prescription opioids is increasing in pediatric populations. Naloxone is the main antidote for treatment. Long-acting opioid toxicity may need close obse...

Dec 10, 2020

Robotic rehabilitation systems have been investigated to assist with motor dysfunction recovery in patients with lower-extremity paralysis caused by central nervous system lesions. These systems are i...

Dec 10, 2020

Postoperative pain after craniotomy is a significant clinical problem which is sometimes underestimated, although moderate or severe pain in early postoperative period complicates up to 60% of cases. ...

Dec 10, 2020

School-based educational programs have shown positive changes in health-related behaviors among adolescents. The aim of this study was to analyze the changes in pain-related knowledge among adolescent...

Dec 10, 2020

Total knee replacement (TKR) normally provides improvements of physical function and reduces pain. However, approximately 20% of the patients report chronic postoperative knee pain. The aims of the pr...

Dec 10, 2020

Rheumatoid arthritis (RA) is a severe inflammatory autoimmune disease, but its treatment has been very difficult. Recently, stem cell-based therapies have opened up possibilities for the treatment of ...

Dec 10, 2020

For several years, hyaluronic acid (HyA) and, more recently, polyacrylamide hydrogel (PHyd) have been used to reduce lameness and pain caused by osteoarthritis. However, there is still a lack of scien...

Dec 10, 2020

To quantitatively profile the T-cell repertoire in the peripheral blood of individuals genetically at risk for RA, namely first-degree relatives of RA patients (RA-FDR) at different phases of disease ...

Dec 07, 2020

The neuroendocrine-stress axis of nonmammalian species is evolutionarily conserved, which makes them useful to serve as important model systems for elucidating the function of the vertebrate stress re...

Dec 07, 2020

To determine reversion rates from chronic migraine to episodic migraine during long-term erenumab treatment.A daily headache diary was completed during the 12-week, double-blind treatment phase of a p...

Dec 07, 2020

The prevalence of migraine and non-migraine headache declines with age.Data from the third visit (2011-2015) of the population-based Heinz Nixdorf Recall study were analysed (n = 2038, 51% women, ...

Dec 07, 2020

Little evidence is available on the role of transcranial direct current stimulation (tDCS) in patients affected by chronic migraine (CM) and medication overuse headache (MOH). We aim to investigate th...

Dec 07, 2020

Fibromyalgia syndrome is a chronic rheumatic disorder characterized by generalized and widespread musculoskeletal pain. It is associated with several secondary symptoms such as psychological and pain-...

Dec 07, 2020

Balance impairment is a frequent disorder in patients with fibromyalgia (FMS), increasing the risk of falls and decreasing physical function and quality of life. In recent years, the use of active the...

Dec 07, 2020

U.S. research examining the illicit drug supply remains rare even though the information could help reduce overdoses. Relatively little is known regarding how often opioids are found in stimulants and...

Dec 07, 2020

Use of various substances, including opioid use is often associated with coming in contact with the law- enforcement agencies. Data are scarce on the unique socio-demographic and clinical correlates f...

Dec 07, 2020

Treatment guidelines recommend targeting both physical and psychological factors in interventions for degenerative lumbar spine disorders. Studying treatment mechanisms gives information on key factor...

Dec 07, 2020

Myofascial pain is one of the most common causes of regional pain yet with no definitive treatment modality. This randomized clinical trial was conducted to assess the efficacy of deep cervical plexus...

Dec 07, 2020

Metabolic dysfunction has been suggested to be involved in musculoskeletal pain; however, few studies have identified metabolic markers associated with multisite musculoskeletal pain (MSMP). This stud...

Dec 07, 2020

 The long-term outcome of facet joint replacement (FJR) still is to be proven. We present a prospective case series of 26 (male-to-female ratio of 1:1; mean age: 61 years) patients undergoing FJR ...