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Pain General

A randomized, controlled trial of a β2-agonist in painful polyneuropathy.

Nov 16, 2020

Experimental data have suggested that in neuropathic pain, tricyclic antidepressants may work solely through a β2-agonist action. The aim of this study was to test if the β2-agonist terbutaline reli...

Hippocampus shape deformation: potential diagnostic biomarker for chronic back pain in women.

Nov 16, 2020

Sex differences in the quality and prevalence of chronic pain are manifold, with females generally presenting higher incidence and severity. Uncovering chronic pain-related sex differences informs neu...

Helmets Protect Pediatric Bicyclists From Head Injury and Do Not Increase Risk of Cervical Spine Injury.

Nov 16, 2020

Only 21 states have mandatory helmet laws for pediatric bicyclists. This study sought to determine the incidence of helmeted riders among pediatric bicyclists involved in a collision and hypothesized ...

Rapid Administration of Ketamine for Abscess Drainage in Children-A Dose Finding Study.

Nov 16, 2020

To estimate the minimum dose and total sedation time of rapidly infused ketamine that achieves 3 to 5 minutes of effective sedation in children undergoing abscess incision and drainage in the emergenc...

Accuracy of Freehand versus Navigated Thoracolumbar Pedicle Screw Placement in Patients with Metastatic Tumors of the Spine.

Nov 16, 2020

To compare the accuracy and breach rates of freehand (FH) versus navigated (NV) pedicle screws in the thoracic and lumbar spine in patients with metastatic spinal tumors.A retrospective review of adul...

Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds.

Nov 16, 2020

CADA compounds selectively down-modulate human cell-surface CD4 protein and are of interest as HIV entry inhibitors and as drugs for asthma, rheumatoid arthritis, diabetes and some cancers. Postulatin...

Septic arthritis post anterior cruciate ligament reconstruction due to Clostridioides difficile.

Nov 16, 2020

Clostridioides difficile is an obligate anaerobe ubiquitous in the environment and is of particular interest in the healthcare setting as a cause of healthcare associated infection usually presenting ...

The otc gene of Streptococcus suis plays an important role in biofilm formation, adhesion, and virulence in a murine model.

Nov 16, 2020

Streptococcus suis (S. suis) is an emerging zoonotic pathogen that can cause meningitis, arthritis, pneumonia, and sepsis. It poses a serious threat to the swine industry and public health worldwide. ...

Allodynia and Disability in Migraine: The Mediating Role of Stress.

Nov 12, 2020

This study sought to investigate the relationship between allodynia, psychological variables, and disability among individuals with migraine.A growing body of research views migraine as a condition of...

Pediatric emergency room visits for neurological conditions: Description and use of pediatric neurologist advice.

Nov 12, 2020

Information on the spectrum and frequencies of pediatric neurological presentations to emergency departments is vital to optimize quality of care. The objective of this study was to determine the inci...

Caregiver Satisfaction and Effectiveness of Teleconsultation in Children and Adolescents With Migraine During the Ongoing COVID-19 Pandemic.

Nov 12, 2020

The ongoing COVID-19 pandemic and the lockdown measures have forced clinicians across the world to look on telemedicine. Although migraine as such seems an ideal option for telemedicine, a systematic ...

Therapeutic Exercise and Pain Neurophysiology Education in Female Patients with Fibromyalgia Syndrome: A Feasibility Study.

Nov 12, 2020

We compared the effects of therapeutic exercise (TE) combined with pain neurophysiology education (PNE) to those of TE in isolation on pain intensity, general fibromyalgia impact, mechanical pain sens...

Clinical, psychological and quality of life differences in fibromyalgia patients from secondary and tertiary healthcare.

Nov 12, 2020

The "funnel effect" of Fibromyalgia (FM) assumes that as patients access healthcare services, they present greater severity and a more complex clinical situation than individuals with FM from the gene...

Phoneutria nigriventer Tx3-3 peptide toxin reduces fibromyalgia symptoms in mice.

Nov 12, 2020

Fibromyalgia is characterized by the amplification of central nervous system pain with concomitant fatigue, sleep, mood disorders, depression, and anxiety. It needs extensive pharmacological therapy. ...

Chronic fluoxetine treatment impairs motivation and reward learning by affecting neuronal plasticity in the central amygdala.

Nov 12, 2020

Background and Purpose The therapeutic effects of fluoxetine (FLX) are believed to be due to its potency for increasing neuronal plasticity and reversing some learning deficits. Nevertheless, a growin...

Direct Sciatic Nerve Electrical Stimulation for Complex Regional Pain Syndrome Type 1.

Nov 12, 2020

Foot and leg pain in complex regional pain syndrome (CRPS) presents a challenge even with neuromodulation techniques such as spinal cord stimulation (SCS). We report our experience with a novo techniq...

Hand Surgery Referral Pattern Preferences Among Primary Care Physicians in Academic Centers in the Southeastern United States.

Nov 12, 2020

Board-certified hand surgeons undergo an additional 1 year of fellowship training after completing 1 of 3 residencies, either orthopedic surgery (OS), plastic surgery (PS), or general surgery (GS). Th...

"Coronavirus could kill me #StayHomeSaveLives": A content and sentiment analysis of tweets by people with arthritis during COVID-19.

Nov 12, 2020

Emerging evidence suggests that people with arthritis are reporting increased physical pain and psychological distress during COVID-19. At the same time, Twitter's daily usage has surged by 23% throug...

A High Psychologic and Somatic Symptom Profile and Family Health Factors Predict New or Persistent Pain during Early Adolescence.

Nov 12, 2020

Persistent or recurrent pain is common among adolescents and is associated with poor functioning. The purpose of this study was to determine whether preteens who present with pain, and higher, co-occu...

Severity of Chronic Pain in German Adolescent School Students - A Cross-sectional Study.

Nov 12, 2020

Prevalence estimates of severe chronic pain in pediatric community samples are rare and inconclusive. This study aimed to (1) examine the prevalence of chronic pain severity grades in school children ...

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