Oct 29, 2020

Heightened rates of prescription opioid misuse have been observed among sexual minority (SM) compared with heterosexual populations. In addition, depression and suicidal ideation are risk factors for...

Oct 29, 2020

To describe the use of tramadol and other analgesics in Denmark focusing on the impact of media attention (June and December 2017) and regulatory actions (September 2017 and January 2018) on the use o...

Oct 29, 2020

Migraine and sleep disorders are common and often burdensome chronic conditions with a high prevalence in the general population, and with considerable socio-economic impact and costs.The existence of...

Oct 29, 2020

Migraine is a severe primary headache disorder that affects about 12% of the population, and it often occurs along with nausea, vomiting, and extreme sensitivity to light and sound. For patients with ...

Oct 29, 2020

is the excessive and inadequately justified concern about potential risks of triptans. We evaluated causes and consequences of non-use of triptans in chronic migraine.Observational study with case-co...

Oct 29, 2020

Fibromyalgia is a chronic condition that results in a significant burden to individuals and society.To investigate the effectiveness of therapies for reducing pain and improving quality of life (QOL) ...

Oct 29, 2020

Interstitial cystitis/bladder pain syndrome (IC/BPS) comprises at least 2 phenotypes. Bladder centric patients typically demonstrate low bladder capacity (BC), often with Hunner lesion (HL), whereas n...

Oct 29, 2020

We studied the effects of a specific cardio training program lasting 5 years on pain and quality of life in fibromyalgia patients.An observational longitudinal pilot study was conducted in 138 fibro...

Oct 29, 2020

The only medication available currently to prevent and treat opioid overdose (naloxone) was approved by the Food and Drug Administration (FDA) nearly 50 years ago. Because of its pharmacokinetic and p...

Oct 29, 2020

The aim of this study is to compare postoperative outcomes and follow-up of two different modifications facilitating surgical technique of frozen elephant trunk (FET) procedure for complex thoracic ao...

Oct 29, 2020

Animal embryogenesis requires a precise coordination between morphogenesis and cell fate specification. During mesoderm induction, mesodermal fate acquisition is tightly coordinated with the morphogen...

Oct 29, 2020

Fibroblast-like synoviocytes (FLSs) are important non-immune cells located mostly in the inner layer of the synovium. Indeed, these cells are specialized mesenchymal cells, implicated in collagen home...

Oct 29, 2020

The objective was to evaluate the relationships between multimorbidity and overall fatigue as well as fatigue subdomains in patients with rheumatoid arthritis (RA).A cross-sectional study of a populat...

Oct 29, 2020

Studies in axial spondyloarthritis (AxSp) have shown that intensity of pain, anxiety, depression, and inflammatory activity are associated with poor sleep quality.To describe mood and sleep disorders ...

Oct 29, 2020

Preterm infants show a higher incidence of cognitive, social and behavioral problems, even in the absence of major medical complications during their stay in the neonatal intensive care unit (NICU). S...

Oct 29, 2020

Persistent Idiopathic Facial Pain (PIFP) is a poorly understood chronic pain syndrome of the face, formerly known as atypical facial pain. It is characterized by a constant painful sensation without n...

Oct 29, 2020

Agonists to subtype C of the Mas-related G-protein-coupled receptors (MrgC) induce pain inhibition after intrathecal (i.t.) administration in rodent models of nerve injury. Here, we investigated wheth...

Oct 26, 2020

Multimodal pain management is the most effective way to treat postsurgical pain. However, the use of opioids for acute pain management has unfortunately been a significant contributor to the current...

Oct 26, 2020

Opioid use disorder (OUD) is characterized by heightened cognitive, physiological, and neural responses to opioid-related cues that are mediated by mesocorticolimbic brain pathways. Craving and withdr...

Oct 26, 2020

Complex regional pain syndrome (CRPS), formerly known as reflex sympathetic dystrophy (RSD), is a difficult to treat condition characterized by debilitating pain and limitations in functional ability....