Oct 08, 2020

To develop and internally validate a multivariable predictive model for days with new-onset migraine headaches based on patient self-prediction and exposure to common trigger factors.Accurate real-tim...

Oct 08, 2020

Fibromyalgia is a musculoskeletal disorder characterized by chronic, widespread muscle pain. This condition is associated with disturbed sleep, which has a direct impact on patient quality of life. Pa...

Oct 08, 2020

The trigeminal nerve complex is a very important and somewhat unique component of the nervous system. It is responsible for the sensory signals that arise from the most part of the face, mouth, nose, ...

Oct 08, 2020

Neuromyelitis optica spectrum disorder (NMOSD) is a type of central nervous system antibody-mediated disease which affects mainly optic nerves and spinal cord, but may also present with acute brainste...

Oct 08, 2020

Investigate the involvement of the histaminergic projections from tuberomammillary nucleus (TMN) to the spinal cord in the modulation of nociception and peripheral edema in a model of monoarthritis.Su...

Oct 08, 2020

This nationwide study aimed to compare use of oxycodone and doctor shopping for oxycodone in 2010 and 2016, and to quantify doctor shopping for oxycodone by sex, age, formulation, and dosage in 2010 a...

Oct 08, 2020

Little is known about risk factors for emergency department (ED) attendance for chronic pain (CP) management and the relative service burden. We examined emergency department (ED) utilisation in patie...

Oct 08, 2020

Sex differences for chronic back pain (cBP) have been reported, with females usually exhibiting greater morbidity, severity and poorer response to treatment. Genetic factors acting in an age-specific ...

Oct 08, 2020

 The Rome IV criteria for primary chronic obstipation help to distinguish between short-term ailments and a chronic pattern of complaints 1. In general, there are several causes of defecation disord...

Oct 08, 2020

Herein, we describe the rapid synthesis of a focused library of trisubstituted imidazo[4,5-b]pyridines and imidazo[4,5-c]pyridines from 2,4-dichloro-3-nitropyridine using the combination of solution-p...

Oct 08, 2020

Androgen deprivation therapy (ADT) is a cornerstone of treatment for advanced prostate cancer (PCa); however, it accelerates the loss of bone mineral density (BMD), which increases fracture risk. Guid...

Oct 05, 2020

The opioid receptor (OPR) family comprises the mu-, delta-, and kappa-opioid, and nociceptin receptors that belong to the superfamily of 7-transmembrane spanning G protein-coupled receptors (GPCRs). T...

Oct 05, 2020

Medication overuse headache (MOH), previously known as analgesic abuse headache or medication misuse headaches, is a common form of chronic headache disorder that has a detrimental impact on health an...

Oct 05, 2020

Migraine is a common and highly disabling headache disorder associated with a substantial socioeconomic burden. Migraine treatments can be categorized as preventive treatment, aimed at reducing the fr...

Oct 05, 2020

This is a comprehensive review of the current literature on the usage of galcanezumab for migraine treatment. It reviews the biology, pathophysiology, epidemiology, diagnosis, and conventional treatme...

Oct 05, 2020

Three-dimensional (3D) printing has emerged as an available visualization tool for clinicians and patients. We sought to utilize patient-specific 3D-printed anatomical modeling for preoperative planni...

Oct 05, 2020

Prescription opioid misuse (POM) has become a critical public health issue in the United States (US), with veteran and military population being especially vulnerable to POM. However, limited behavior...

Oct 05, 2020

This randomized, controlled trial evaluated whether a brief educational program (i.e., Scenario-Tailored Opioid Messaging Program [STOMP]) would improve parental opioid risk knowledge, perceptions, an...

Oct 05, 2020

Quadriparesis after intramuscular trigger point injections for myofascial pain syndrome has been rarely reported in the literature. A 37-year-old male patient presented with myofascial pain syndrome a...

Oct 05, 2020

The present paper consists of two separate studies in which the overarching aim was to examine the relationships between caregiver-child behaviours in the vaccination context (infant and preschool) an...