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Pain General

Brain Metabolism and Structure in Chronic Migraine.

Oct 01, 2020

The purpose of this paper is to review and synthesize current literature in which neurochemical and structural brain imaging were used to investigate chronic migraine (CM) pathophysiology and to furth...

Evaluation of Patients with Insufficient Efficacy and/or Tolerability to Triptans for the Acute Treatment of Migraine: A Systematic Literature Review.

Oct 01, 2020

Use of triptans for acute treatment of migraine is associated with insufficient efficacy and/or tolerability in approximately 30-40% of people. We conducted a systematic literature review (SLR) to syn...

The Effect of Anesthesia Type During Delivery on Neonatal Otoacoustic Emission Hearing Test Results: A Tertiary Center Experience.

Oct 01, 2020

Hearing is essential for the healthy development of an infant as language is one of the main stimulants of intellectual capacity. We investigate the effect of anesthesia type during delivery on neonat...

Key Evidence Supporting Prescription Opioids Approved by the U.S. Food and Drug Administration, 1997 to 2018.

Oct 01, 2020

Little is known about the evidence required by the U.S. Food and Drug Administration (FDA) for new approvals of opioid analgesics.To characterize the quality of safety and efficacy data in new drug ap...

Pool-based exercise for amelioration of pain in adults with fibromyalgia syndrome: A systematic review and meta-analysis.

Oct 01, 2020

To evaluate the effects of pool-based exercises on pain symptomatology among adults with fibromyalgia syndrome.A systematic review and meta-analysis were carried out using PRISMA guidelines. Database ...

Influence of Oxidative Stress-Related Genes on Susceptibility to Fibromyalgia.

Oct 01, 2020

Fibromyalgia (FM) is a complex syndrome to diagnose and treat due to its unknown etiology. However, previous studies reported that patients with FM suffer from oxidative stress.In this study, we inves...

Postoperative Pain Management in Patients With Ulcerative Colitis.

Oct 01, 2020

Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders of the gastrointestinal tract including ulcerative colitis (UC) and Crohn's disease. Pain management can be challenging in...

DIFFERENCES IN DEPRESSION, ANXIETY AND STRESS DISORDERS BETWEEN FIBROMYALGIA ASSOCIATED WITH RHEUMATOID ARTHRITIS AND PRIMARY FIBROMYALGIA.

Oct 01, 2020

Fibromyalgia (FM) was frequently observed in patients with rheumatoid arthritis (RA). We aimed to evaluate the differences in psychiatric comorbidities and life adversities between patients with RA+FM...

Retrospective comparison between a two- and three-component ankle arthroplasty: clinical and functional evaluation via gait analysis.

Oct 01, 2020

Total ankle arthroplasty is intended to restore physiological joint function in case of severe ankle arthritis. However, little is known about the functional outcome associated to different prosthesis...

Quantitative Imaging in Inflammatory Arthritis: Between Tradition and Innovation.

Oct 01, 2020

Radiologic imaging is crucial for diagnosing and monitoring rheumatic inflammatory diseases. Particularly the emerging approach of precision medicine has increased the interest in quantitative imaging...

Spontaneous Neuronal Plasticity in the Contralateral Motor Cortex and Corticospinal Tract after Focal Cortical Infarction in Hypertensive Rats.

Oct 01, 2020

In this study, we investigated the spontaneous neural plasticity on the contralateral side in hypertensive rats, including the expression of nerve growth factors (synaptophysin [SYN] and growth-associ...

Pain or No Pain, We Will Give You Opioids: Relationship Between Number of Opioid Pills Prescribed and Severity of Pain after Operation in US vs Non-US Patients.

Sep 28, 2020

Patients in the US receive disproportionally higher amounts of opioids following surgery compared to their non-US counterparts. We aimed to assess the relationship between perceived pain severity afte...

A non-opioid analgesic implant for sustained post-operative intraperitoneal delivery of lidocaine, characterized using an ovine model.

Sep 28, 2020

Appropriate management of post-operative pain is an ongoing challenge in surgical practice. At present, systemic opioid administration is routinely used for analgesia in the post-operative setting. Ho...

Long term pre-treatment opioid use trajectories in relation to opioid agonist therapy outcomes among people who use drugs in a Canadian setting.

Sep 28, 2020

Opioid agonist therapy (OAT) models are generally provided without consideration of how pre-treatment characteristics may be associated with outcome. Therefore, we aimed to first characterize longitud...

Medication Overuse Withdrawal in Children and Adolescents Does Not Always Improve Headache: A Cross-Sectional Study.

Sep 28, 2020

MOH can be diagnosed in subjects with headache occurring 15 days/month in association with a regular medication overuse, but its existence is not universally accepted. ICHD-3 redefined criteria for M...

Drug-naïve Egyptian females with migraine are more prone to sexual dysfunction than those with tension-type headache: a cross-sectional comparative study.

Sep 28, 2020

Headache is one of the chronic disorders that can trigger sexual dysfunction due to complex mechanisms. This study recruited 120 consecutive patients from our outpatient clinics with migraine (n =�...

Sumatriptan alleviates radiation-induced oral mucositis in rats by inhibition of NF-kB and ERK activation, prevention of TNF-α and ROS release.

Sep 28, 2020

Oral mucositis caused by radiation therapy is a common problem in cancer patients, especially those with head and neck cancer. Numerous experimental and clinical studies have attempted to find a drug ...

Associations of Sleep Disturbance, Atopy, and Other Health Measures with Chronic Overlapping Pain Conditions.

Sep 28, 2020

To quantify the contributions of atopic disorders, sleep disturbance, and other health conditions to five common pain conditions.This cross-sectional analysis used data from 655 participants in the OP...

Associations of Psychologic Factors with Multiple Chronic Overlapping Pain Conditions.

Sep 28, 2020

To characterize psychologic functioning across five chronic overlapping pain conditions (COPCs)-temporomandibular disorders, fibromyalgia, low back pain, headache, and irritable bowel syndrome-and the...

Prescription of exercises for the treatment of chronic pain along the continuum of nociplastic pain: a systematic review with meta-analysis.

Sep 28, 2020

To compare different exercise prescriptions for patients with chronic pain along the continuum of nociplastic pain: fibromyalgia, chronic whiplash-associated disorders (CWAD), and chronic idiopathic n...

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