Sep 28, 2020

The CB R agonist AM1710, examined in animal models of peripheral neuropathy, is effective in controlling aberrant light touch sensitivity, referred to as mechanical allodynia. However, nonspecific bin...

Sep 28, 2020

Spinal cord injury (SCI) induces both motor and sensory dysfunctions. We wondered whether miR-30b could promote primary sensory neuron (PSN) axon growth in inhibitory microenvironment. The neurite gro...

Sep 28, 2020

Prior work in a cohort of youth with functional abdominal pain (FAP) identified patient subgroups (High Pain Dysfunctional, High Pain Adaptive, Low Pain Adaptive) that predicted differences in the cou...

Sep 28, 2020

Rheumatoid arthritis (RA) is a chronic autoimmune disease that produces synovial membrane inflammation and causes progressive articular damage with function lossing. There is some controversy about wh...

Sep 28, 2020

Clinical outcomes after reconstruction for multiligamentous knee injury (MLKI) can be consistently favorable. However, recent implants and technique advances may allow for improvement in outcomes. Our...

Sep 28, 2020

Spinal cord injury (SCI) is an area of key interest in military medicine but has not been studied among the US Army Special Forces (SF), the most elite group of US soldiers. SF soldiers make up a disp...

Sep 24, 2020

Opioid use disorder (OUD) represents a large and pervasive global public health challenge. Previous genetic studies have demonstrated the significant heritability of OUD and identified several single-...

Sep 24, 2020

For decades the broad role of opioids in addiction, neuropsychiatric disorders, and pain states has been somewhat well established. However, in recent years, with the rise of technological advances, n...

Sep 24, 2020

To demonstrate that calcitonin gene-related peptide (CGRP) induces headache exacerbation with migraine-like features in patients with persistent post-traumatic headache (PTH) attributed to mild trauma...

Sep 24, 2020

Neurocysticercosis (NCC) is a disease caused by infection of the central nervous system with the larval stage of the tapeworm This disease is endemic in many parts of the world, including Africa, Asi...

Sep 24, 2020

Chronic backache remains among common causes of attendance in orthopaedic, pain and neurology clinics and requires a detailed workup for the management of these patients. As per literature, fibromyalg...

Sep 24, 2020

Fibromyalgia is a common rheumatic disease, which is thought to be a neuroendocrine dysregulation disorder. Patients' quality of life is severely affected by this disease. Though neural therapy, as a ...

Sep 24, 2020

Bess beetles are sapro-xillophagous insects that inhabit decaying logs. They display sub-social behavior and acoustic communication. Adults produce sounds with an abdomino-alary stridulatory system. T...

Sep 24, 2020

Persistent post-surgical pain is common among patients undergoing surgery, is detrimental to patients' quality of life, and can precipitate long-term opioid use. The purpose of this randomized control...

Sep 24, 2020

To compare enhanced recovery after surgery (ERAS) and conventional care (CC) protocols on outcomes of laparoscopic hysterectomy (LH) performed in the afternoon.A single-center randomized controlled tr...

Sep 24, 2020

Pregabalin is a drug for neuropathic pain. The antipronociceptive properties of pregabalin have led to its recent use as an adjuvant to the multimodal postoperative pain regimen. This meta-analysis wa...

Sep 24, 2020

High risks of falls have been reported in older adults with chronic pain but chronic pain similarly affects adults of all ages. This cross-sectional study aimed to determine the prevalence of falls an...

Sep 24, 2020

Clinical guidelines recommend that healthcare providers assist children to understand their experience of persistent pain, with pain science education a key component of clinical management in pediatr...

Sep 24, 2020

Fibromyalgia (FM) is a chronic disease whose symptoms may cause altered walking pattern, which is important given the relevance of walking in daily life activities. These activities use to require the...

Sep 24, 2020

The relationship between functional disability and MRI-inflammation has been studied for the hands, but has not been well established for the feet, even though walking-difficulties are common. Therefo...