Sep 14, 2020

Interleukin-15 (IL-15) is a member of the IL-2 family of cytokines, which use receptor complexes containing the common gamma (γ) chain for signaling. IL-15 plays important roles in innate and adaptat...

Sep 14, 2020

The use of controlled substances like cocaine increases the risk of cardiovascular disease (CVD) and myocardial infarction (MI). However, outside of alcohol and tobacco, substance use is not included ...

Sep 11, 2020

Ankle sprains are one of the most common types of musculoskeletal injuries. Physiotherapy is routinely given to patients with ankle sprains. This study aims to evaluate the efficacy of supervised phys...

Sep 10, 2020

Achilles tendinopathy (AT), or Achilles tendinitis, is an injury of the Achilles tendon, which connects the calf muscle to the heel bone. The usual care given to patients with AT does not result in po...

Sep 10, 2020

Chronic pain often predicts the onset of psychological distress. Symptoms including anxiety and depression after pain chronification reportedly are caused by brain remodeling/recruitment of the limbic...

Sep 10, 2020

Migraine is a common and debilitating neurological disorder characterized by recurrent attacks of moderate to severe throbbing headache accompanied by nausea, vomiting and photophobia/phonophobia. Bec...

Sep 10, 2020

Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by recurrent thunderclap headaches associated with segmental vasoconstriction of cerebral arteries, which may result in intracrani...

Sep 10, 2020

This study aimed to investigate the clinical predictors of post-ictal headache (PIH) in patients with epilepsy in a tertiary center in Brazil.302 individuals with adult-onset epilepsy were followed fo...

Sep 10, 2020

Secondary salinization of freshwater ecosystems is of increasing global concern. One of the main causes are the effluents of the potash mining industry containing high concentrations of major ions (Cl...

Sep 10, 2020

Rheumatoid arthritis (RA) is a chronic autoimmune disease that leads to joint deformity and disability, as well as muscle involvement. Sarcopenia is characterized by a progressive age-related loss of ...

Sep 10, 2020

Rheumatoid arthritis (RA) is complex autoimmune system disease and significant impact on the health of population in our world. Numerous studies confirmed that genetic factors play a crucial role in t...

Sep 10, 2020

Evidence in preclinical models of chronic pain and human psychophysical investigations has suggested that alterations in endogenous brainstem pain-modulation circuit functioning are critical for the i...

Sep 10, 2020

We aimed to investigate whether small-fibre pathology, a common skin biopsy finding in patients with fibromyalgia, implies clinically important abnormalities of somatosensory system function and verif...

Sep 10, 2020

The aim of this study was to evaluate the psychometric properties of the Chilean version of the Fibromyalgia Survey Questionnaire (FSQ).Women with fibromyalgia (FM; n = 214), women with rheumatoid art...

Sep 10, 2020

The current study was designed to evaluate the translation of clinical trial outcomes and clinical guidelines for the treatment of fibromyalgia (FM) into an intensive multicomponent clinical program e...

Sep 10, 2020

The objectives of this study are to assess perioperative opioid use in patients undergoing knee surgery and to examine the relationship between preoperative opioid use and 2-year postoperative patient...

Sep 10, 2020

The purpose of this study was to evaluate Patient-Reported Outcomes Measurement Information System physical function (PROMIS PF) 2 years following knee surgery, and identify preoperative factors assoc...

Sep 10, 2020

Serum sickness-like reactions (SSLR) are defined by the presence of rash (primarily urticaria), and joint complaints (arthralgia/arthritis) that are believed to occur due to a non-IgE mediated respons...

Sep 07, 2020

To describe the perioperative opioid demand in a large population of patients undergoing lower extremity fracture fixation and to evaluate mental disorders such as substance abuse as risk factors for ...

Sep 07, 2020

The opioid epidemic continues to cause significant morbidity and mortality. Although there are effective medications for opioid use disorder (OUD), a minority of patients receive these treatments. OUD...