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Pain General

[Effectiveness of intra-articular anesthesia in knee arthroscopy].

Aug 10, 2020

Knee arthroscopy is one of the most commonly performed procedures. General anesthesia and spinal blockage are the most common forms of anesthesia. We consider that this surgery can be managed with int...

The association of physical activity with all-cause and cause-specific mortality

Aug 07, 2020

Inadequate physical activity is a global health problem and is responsible for 6-10% of major chronic illnesses worldwide. This study aims at deriving a relation between recommended physical activity ...

Serum Activity Against G Protein-Coupled Receptors and Severity of Orthostatic Symptoms in Postural Orthostatic Tachycardia Syndrome.

Aug 06, 2020

Background Postural orthostatic tachycardia syndrome (POTS) is characterized by excessive heart rate increase on standing and orthostatic intolerance. Previous data indicate autoimmune involvement. We...

Novel hybrid compounds, opioid agonist+melanocortin 4 receptor antagonist, as efficient analgesics in mouse neuropathic pain model.

Aug 06, 2020

When the nerve tissue is injured, endogenous agonist of melanocortin type 4 (MC4) receptor, α-MSH, exerts tonic pronociceptive action in the central nervous system, contributing to sustaining the neu...

Efficacy and safety of erenumab in women with a history of menstrual migraine.

Aug 06, 2020

We performed a post hoc, subgroup analysis of a phase 3, randomized, double-blind, placebo-controlled study of erenumab for prevention of episodic migraine (STRIVE) to determine the efficacy and safet...

A Qualitative Study to Assess the Content Validity of the 24-Hour Migraine Quality of Life Questionnaire in Patients with Migraine.

Aug 06, 2020

A concept elicitation, cognitive debriefing, and usability study was undertaken to: (1) explore migraine symptoms and day-to-day impacts; (2) determine the comprehensiveness and comprehensibility of t...

Clinical and Radiological Outcomes of Less Invasive Temporary Internal Distraction Followed by Staged Pedicle Screw Instrumentation in Adolescents with Severe Idiopathic Scoliosis at minimum two years' follow-up.

Aug 06, 2020

Temporary internal distraction rod is one of the surgical options in severe scoliosis to avoid preoperative halo traction or vertebral column resection. This technique can be applied in a single sessi...

Outcomes are comparable using free bone block autografts versus allografts for the management of anterior shoulder instability with glenoid bone loss: a systematic review and meta-analysis of "The Non-Latarjet".

Aug 06, 2020

Glenoid augmentation using free bone blocks for anterior shoulder instability has been proposed as an alternative to or bail-out for the Latarjet procedure. The purpose of this investigation was to sy...

Acute Effects of Turmeric Extracts on Knee Joint Pain: A Pilot, Randomized Controlled Trial.

Aug 06, 2020

Turmeric extracts (TEs) have been shown to be suitable as a pain treatment for human joint arthritis. In a pilot, randomized clinical trial, 68 individuals with mild/moderate knee joint pain (KJP) con...

Injectable PLGA-coated ropivacaine produces a long-lasting analgesic effect on incisional pain and neuropathic pain.

Aug 06, 2020

The management of persistent postsurgical pain and neuropathic pain remains a challenge in the clinic. Local anesthetics have been widely used as simple and effective treatment for these two disorders...

Comorbid Pain and Cognitive Impairment in a Nationally Representative Adult Population: Prevalence and Associations with Health Status, Health Care Utilization, and Satisfaction with Care.

Aug 06, 2020

Using a nationally representative sample of adults and pain definitions consistent with the United States National Pain Strategy, we examined the associations of pain and cognitive impairment (CI) wit...

Impact of Depression and Anxiety Symptoms on Patient-Reported Outcomes in Patients With Migraine: Results From the American Registry for Migraine Research (ARMR).

Aug 06, 2020

The association between migraine, depression, and anxiety has been established, but the impact of these psychiatric comorbidities on functional impairment in people with migraine has been under-invest...

Hypnotic intervention in people with fibromyalgia: A randomized controlled trial.

Aug 06, 2020

Fibromyalgia affects the quality of life of the patients, as well as their family. It also affects their social, labor, physical, and psychological dynamics. We aimed to evaluate the effectiveness of ...

Decreased sleep quality in patients with systemic lupus erythematosus: a meta-analysis.

Aug 06, 2020

To obtain a reliable estimation on the sleep quality in patients with systemic lupus erythematosus (SLE) and identify the main sleep problems, a meta-analysis was performed.Up to March 21, 2020, PubMe...

Best Practices for Chiropractic Management of Patients with Chronic Musculoskeletal Pain: A Clinical Practice Guideline.

Aug 06, 2020

To develop an evidence-based clinical practice guideline (CPG) through a broad-based consensus process on best practices for chiropractic management of patients with chronic musculoskeletal (MSK) pai...

Where and how alpha-synuclein pathology spreads in Parkinson's disease.

Aug 06, 2020

In Parkinson's disease (PD), neuronal alpha-synuclein aggregates are distributed throughout the nervous system, including the brain, spinal cord, sympathetic ganglia, submandibular gland, enteric nerv...

Enhanced Recovery After Surgical Correction of Adolescent Idiopathic Scoliosis.

Aug 06, 2020

Few publications in the literature examine enhanced recovery after scoliosis surgery (ERAS) in children, despite significant scientific interest in adults. The objective of the current study was to de...

Prevalence of high-riding vertebral artery: a meta-analysis of the anatomical variant affecting choice of craniocervical fusion method and its outcome.

Aug 06, 2020

A high-riding vertebral artery (HRVA) is defined as C2 isthmus height ≤ 5 mm or/and internal height ≤ 2 mm measured 3 mm lateral to the border of the spinal canal. Its reported prevalence varies w...

Sustainable effects of 8-year intermittent spinal cord stimulation in a patient with thalamic post-stroke pain.

Aug 06, 2020

Central post-stroke pain (CPSP) is a central neuropathic pain syndrome secondary to a cerebrovascular accident. CPSP treatment usually begins with medication; however, this is associated with inadequa...

Community Attitudes Toward Opioid Use Disorder and Medication for Opioid Use Disorder in a Rural Appalachian County.

Aug 03, 2020

To evaluate community attitudes concerning opioid use disorder (OUD) and medication for opioid use disorder (MOUD) in a rural community, and to plan educational initiatives to reduce stigma surroundin...

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