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Pain General

Treatment effects on pain catastrophizing and cutaneous allodynia symptoms in women with migraine and overweight/obesity.

Jul 16, 2020

Pain catastrophizing and cutaneous allodynia represent two risk factors for greater headache-related disability. Yet, there is limited knowledge of the extent to which these risk factors are modifiabl...

Stroke-like migraine attacks after radiation therapy (SMART) syndrome-a case series and review.

Jul 16, 2020

Cranial irradiation is used both prophylactically and for the treatment of brain tumors. There are various complications associated with it. The rare complication of stroke-like migraine attacks after...

Syrian female war refugees: preliminary fibromyalgia and insomnia screening and treatment trends.

Jul 16, 2020

Fibromyalgia (FM) is a chronic disorder characterised by chronic widespread pain, fatigue and sleep disturbances with higher prevalence in females. Psychological factors contribute largely to FM. Alth...

A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia.

Jul 16, 2020

Alterations in cellular energy metabolism have been implicated in chronic pain suggesting a role for mitochondrial DNA (mtDNA). Previous studies reported associations of a limited number of mtDNA poly...

Gulf war illness, post-HPV vaccination syndrome, and Macrophagic Myofasciitis. Similar disabling conditions possibly linked to vaccine-induced autoimmune dysautonomia.

Jul 16, 2020

More than one-fourth of all Persian Gulf War coalition soldiers remain seriously ill. Several epidemiological studies suggest a link between multiple vaccinations at the time of the military operation...

The International Spinal Cord Injury Survey: The Way Forward.

Jul 16, 2020

As a community survey of people living with spinal cord injury in 22 countries, representing all six of WHO regions of the world, InSCI is one of a very few surveys that highlights, not only the basic...

The cervical spine as a predominant site of cerebrospinal fluid leak: Preliminary results using the overflow leak test.

Jul 16, 2020

Cerebrospinal fluid hypovolemia (CSFH) is usually treated via an epidural blood patch (EBP). Accurate placement of the EBP at the site of cerebrospinal fluid (CSF) leakage is required for the successf...

Opioid Prescribing Patterns After Anorectal Surgery.

Jul 16, 2020

Anorectal procedures are frequently performed and have the potential to be particularly painful. There are no evidence-based guidelines regarding opioid prescribing after anorectal surgery and limited...

Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis.

Jul 16, 2020

TNF plays a key role in immune-mediated inflammatory diseases including rheumatoid arthritis (RA) and spondyloarthritis (SpA). It remains incompletely understood how TNF can lead to different disease ...

Media supplementation for targeted manipulation of monoclonal antibody galactosylation and fucosylation.

Jul 16, 2020

Monoclonal antibodies (mAbs) are critically important biologics as the largest class of molecules used to treat cancers, rheumatoid arthritis, and other chronic diseases. Antibody glycosylation is a c...

Testosterone protects against the development of widespread muscle pain in mice.

Jul 16, 2020

Chronic widespread pain conditions are more prevalent in women than men suggesting a role for gonadal hormones in the observed differences. Previously, we showed female mice, compared to male, develop...

Peripheral nerve injury and sensitization underlie pain associated with oral cancer perineural invasion.

Jul 16, 2020

Cancer invading into nerves, termed perineural invasion (PNI), is associated with pain. Here we show that oral cancer patients with PNI report greater spontaneous pain and mechanical allodynia compare...

Offset analgesia identifies impaired endogenous pain modulation in pediatric chronic pain disorders.

Jul 16, 2020

Offset analgesia (OA), a psychophysical test of endogenous pain inhibition, is diminished in many adult chronic pain disorders but OA has not been investigated in youth with chronic pain disorders. Th...

30-day Readmissions and Reoperations after Total Elbow Arthroplasty: A National Database Study.

Jul 16, 2020

The purpose of this study was to determine the rate of short-term complications after TEA and identify predictors of readmission and reoperation. We hypothesized that TEA performed for acute elbow tra...

The state of the science in opioid policy research.

Jul 13, 2020

Characterize the state of the science in opioid policy research based on a literature review of opioid policy studies.We conducted a scoping review of studies evaluating the impact of U.S. state-level...

Substance use patterns and health profiles among US adults who use opioids, methamphetamine, or both, 2015-2018.

Jul 13, 2020

Methamphetamine use, with and without opioids, has increased substantially, but little is known about the sociodemographic characteristics, substance use patterns, or health profiles of individuals wh...

Hydrocephalus-related quality of life as assessed by children and their caregivers.

Jul 13, 2020

Hydrocephalus is a chronic medical condition that has a significant impact on children and their caregivers. The objective of this study was to measure the quality of life (QOL) of children with hydro...

Menstrual migraine among Spanish university students.

Jul 13, 2020

This study sought to determine the prevalence of menstrual migraine among female university students at the Nursing Faculty of Ciudad Real and to determine possible risk factors.A cross-sectional obse...

Cortical spreading depolarisation-induced facial hyperalgesia, photophobia and hypomotility are ameliorated by sumatriptan and olcegepant.

Jul 13, 2020

Cortical spreading depolarisation (CSD), the neural mechanism underlying migraine aura, may cause headache by sensitising the trigeminal system. Photophobia, the most bothersome accompanying symptom d...

Comorbid pain experiences in young women with dysmenorrhea.

Jul 13, 2020

The association among dysmenorrhea, chronic pain, and conditions classified as central sensitivity syndromes (CSS) is largely unknown. We investigated the co-occurrence of dysmenorrhea with chronic pa...

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