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Pain General

[Non-inflammatory muscle pain].

Jul 06, 2020

Muscle pain as a common symptom in daily practice frequently occurs as a non-specific accompanying symptom in multiple internal and neurological diseases. Primarily inflammatory or autoimmune muscular...

Flexible endoscope visualization to assist in the removal of a string of 10 schwannomas at the cauda equina: technical case report.

Jul 06, 2020

Bead-like schwannomas at the cauda equina are rare but benign intraspinal tumors. They can involve multiple nerve roots and spread within the spinal canal, and open resection would cause significant t...

Blood glutamate scavengers and exercises as an effective neuroprotective treatment in mice with spinal cord injury.

Jul 06, 2020

Excitotoxicity due to neuronal damage and glutamate release is one of the first events that leads to the progression of neuronal degeneration and functional impairment. This study is based on a paradi...

A Systematic Literature Review of Residual Symptoms and Unmet Need in Patients with Rheumatoid Arthritis.

Jul 06, 2020

To evaluate the nature and burden of residual disease in rheumatoid arthritis (RA) in patients who meet treatment targets. Secondly, for those who did not meet targets, evaluate how much is due to pat...

species infections in humans: a systematic review.

Jul 06, 2020

species have been recognized to cause infections in immunocompromised individuals. The purpose of this study was to systemically review all published cases of infections in humans and describe the e...

The impact of income support systems on healthcare quality and functional capacity in workers with low back pain: a realist review.

Jul 06, 2020

Low back pain (LBP) is a leading cause of work disability. While absent from work, workers with LBP may receive income support from a system such as workers' compensation or social security. This stud...

Does a screening trial for spinal cord stimulation in patients with chronic pain of neuropathic origin have clinical utility and cost-effectiveness (TRIAL-STIM)? a randomised controlled trial.

Jul 06, 2020

Spinal cord stimulation (SCS) is an established treatment of chronic neuropathic pain. Although a temporary SCS screening trial is widely used to determine whether a patient should receive permanent S...

In silico feasibility assessment of extracorporeal delivery of low-intensity pulsed ultrasound to intervertebral discs within the lumbar spine.

Jul 06, 2020

Low intensity pulsed ultrasound (LIPUS) may have utility for noninvasive treatment of discogenic lower back pain through stimulating, remodeling and accelerating healing of injured or degenerated inte...

Cardiovascular and somatic comorbidities and sleep measures using three hypopnea criteria in mild obstructive sleep-disordered breathing: sex, age and body mass index differences in a retrospective sleep clinic cohort.

Jul 06, 2020

To describe sex, age and body mass index (BMI) differences in comorbidities and polysomnography (PSG) measures, categorized using three different apnea-hypopnea index (AHI) criterion, in sleep clinic ...

Effect of Statin Use on Cardiovascular Events and All-Cause Mortality and in Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-Analysis involving 148,722 Participants.

Jul 06, 2020

Immune-mediated inflammatory diseases (IMIDs) are associated with an increased risk of premature cardiovascular disease and all-cause mortality. Given lipid-lowering and anti-inflammatory properties, ...

Cleft Palate Repair: A New Maxillary Nerve Block Approach.

Jul 02, 2020

To introduce a different approach for maxillary nerve block (MNB), in cleft palate repair. To reduce the use of opioids during surgery and to prevent frequent respiratory complications by means of an ...

Risk Factors for Prolonged Opioid Use and Effects of Opioid Tolerance on Clinical Outcomes After Anterior Cervical Discectomy and Fusion Surgery.

Jul 02, 2020

Retrospective study.The aim of this study was to determine risk factors for prolonged opioid use and to investigate whether opioid-tolerance affects patient-reported outcomes following anterior cervic...

Two-hour infusion of vasoactive intestinal polypeptide induces delayed headache and extracranial vasodilation in healthy volunteers.

Jul 02, 2020

In recent years, vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptides (PACAPs) have gained special interest in headache science. VIP and PACAPs (two isoforms, PA...

Cinnarizine as alternative recommendation for migraine prophylaxis: a narrative review.

Jul 02, 2020

Despite the available prophylactic and acute drugs for migraine management, this disabling disorder remains undertreated especially among pediatrics. In this review, the authors aim at assessing the p...

Mechanism of Action of OnabotulinumtoxinA in Chronic Migraine: A Narrative Review.

Jul 02, 2020

To review the literature on the mechanism of action of onabotulinumtoxinA in chronic migraine.OnabotulinumtoxinA is a chronic migraine preventive treatment that significantly reduces headache frequenc...

Repetitive transcranial magnetic stimulation of the prefrontal cortex for fibromyalgia syndrome: a randomised controlled trial with 6-months follow up.

Jul 02, 2020

Fibromyalgia Syndrome (FMS), is a chronic pain disorder with poorly understood pathophysiology. In recent years, repetitive transcranial magnetic stimulation (rTMS) has been recommended for pain reli...

Prevalence of obstructive sleep apnea in female patients with fibromyalgia.

Jul 02, 2020

To determine the prevalence of obstructive sleep apnea in female patients with fibromyalgia (FM)presenting to physical therapy outpatient clinics.The 36-item short form health survey (SF-36) questionn...

Back Pain in Children and Adolescents.

Jul 02, 2020

Back pain is a relatively common presenting symptom in children and adolescents. Typical causes include muscle strain or spasm, spinal deformities (e.g., Scheuermann kyphosis, adolescent idiopathic sc...

Development of a New Emergency Medicine Spinal Immobilization Protocol for Pediatric Trauma Patients and First Applicability Test on Emergency Medicine Personnel.

Jul 02, 2020

The purpose of this study was to (i) develop a protocol that supports decision making for prehospital spinal immobilization in pediatric trauma patients based on evidence from current scientific liter...

Chronic Musculoskeletal Pain and Foot Reaction Time in Older Adults.

Jul 02, 2020

This cross-sectional study examines the association between chronic musculoskeletal pain and foot reaction time (RT) among older community-living adults. Participants were 307 adults aged 71 years and...

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