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Pain General

Effect of Statin Use on Cardiovascular Events and All-Cause Mortality and in Immune-Mediated Inflammatory Diseases: A Systematic Review and Meta-Analysis involving 148,722 Participants.

Jul 06, 2020

Immune-mediated inflammatory diseases (IMIDs) are associated with an increased risk of premature cardiovascular disease and all-cause mortality. Given lipid-lowering and anti-inflammatory properties, ...

Cleft Palate Repair: A New Maxillary Nerve Block Approach.

Jul 02, 2020

To introduce a different approach for maxillary nerve block (MNB), in cleft palate repair. To reduce the use of opioids during surgery and to prevent frequent respiratory complications by means of an ...

Risk Factors for Prolonged Opioid Use and Effects of Opioid Tolerance on Clinical Outcomes After Anterior Cervical Discectomy and Fusion Surgery.

Jul 02, 2020

Retrospective study.The aim of this study was to determine risk factors for prolonged opioid use and to investigate whether opioid-tolerance affects patient-reported outcomes following anterior cervic...

Two-hour infusion of vasoactive intestinal polypeptide induces delayed headache and extracranial vasodilation in healthy volunteers.

Jul 02, 2020

In recent years, vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptides (PACAPs) have gained special interest in headache science. VIP and PACAPs (two isoforms, PA...

Cinnarizine as alternative recommendation for migraine prophylaxis: a narrative review.

Jul 02, 2020

Despite the available prophylactic and acute drugs for migraine management, this disabling disorder remains undertreated especially among pediatrics. In this review, the authors aim at assessing the p...

Mechanism of Action of OnabotulinumtoxinA in Chronic Migraine: A Narrative Review.

Jul 02, 2020

To review the literature on the mechanism of action of onabotulinumtoxinA in chronic migraine.OnabotulinumtoxinA is a chronic migraine preventive treatment that significantly reduces headache frequenc...

Repetitive transcranial magnetic stimulation of the prefrontal cortex for fibromyalgia syndrome: a randomised controlled trial with 6-months follow up.

Jul 02, 2020

Fibromyalgia Syndrome (FMS), is a chronic pain disorder with poorly understood pathophysiology. In recent years, repetitive transcranial magnetic stimulation (rTMS) has been recommended for pain reli...

Prevalence of obstructive sleep apnea in female patients with fibromyalgia.

Jul 02, 2020

To determine the prevalence of obstructive sleep apnea in female patients with fibromyalgia (FM)presenting to physical therapy outpatient clinics.The 36-item short form health survey (SF-36) questionn...

Back Pain in Children and Adolescents.

Jul 02, 2020

Back pain is a relatively common presenting symptom in children and adolescents. Typical causes include muscle strain or spasm, spinal deformities (e.g., Scheuermann kyphosis, adolescent idiopathic sc...

Development of a New Emergency Medicine Spinal Immobilization Protocol for Pediatric Trauma Patients and First Applicability Test on Emergency Medicine Personnel.

Jul 02, 2020

The purpose of this study was to (i) develop a protocol that supports decision making for prehospital spinal immobilization in pediatric trauma patients based on evidence from current scientific liter...

Chronic Musculoskeletal Pain and Foot Reaction Time in Older Adults.

Jul 02, 2020

This cross-sectional study examines the association between chronic musculoskeletal pain and foot reaction time (RT) among older community-living adults. Participants were 307 adults aged 71 years and...

Exposure to contact sports results in maintained performance during experimental pain.

Jul 02, 2020

During pain, motor performance tends to decline. However, athletes who engage in contact sports are able to maintain performance despite the inherent pain that accompanies participation. This may be t...

An Initial Psychometric Evaluation of the Pain Concepts Questionnaire in a Low-SES Setting.

Jul 02, 2020

The examination of pain beliefs for chronic pain assessment and treatment has been a growing area of interest. A variety of questionnaires have been developed to assess pain beliefs, however, these qu...

Rheumatic Diseases Associated With Posterior Reversible Encephalopathy Syndrome.

Jul 02, 2020

Posterior reversible encephalopathy syndrome (PRES) is an acute neurological syndrome. There are many reports of PRES occurring in the setting of rheumatic diseases. However, it remains uncertain whet...

Percutaneous Radiofrequency Ablation of the Posterior and Anterior Interosseous Nerves for Chronic Wrist Pain: A Novel Technique.

Jul 02, 2020

The treatment of chronic wrist pain, due to posttraumatic, degenerative, or inflammatory arthritis, is challenging to adequately manage. The ideal surgical procedure should preserve wrist mobility and...

Fatal accident involving a welder employed by a shipping container company, associated with the use of tramadol and antidepressant agents.

Jul 02, 2020

The widespread use of opioids for the treatment of moderate or severe acute and chronic pain has become a public health problem due to the physical and psychological dependence and tolerance they prod...

Irukandji-like syndrome caused by single-tentacle box jellyfish found in Thailand, 2007-2019.

Jul 02, 2020

Irukandji syndrome definition is still widely misunderstood. Irukandji-like syndrome is more unclear than Irukandji syndrome. This study aimed to describe Irukandji-like syndrome in cases involving st...

Anti-Cyclic Citrullinated Peptide Antibodies Correlate to Ultrasound Synovitis in Rheumatoid Arthritis Better Than C-Reactive Protein.

Jul 02, 2020

The aim of this study was to compare ultrasound (US) grading and laboratory measures in patients with rheumatoid arthritis.Two-hundred four patients with rheumatoid arthritis who received US evaluatio...

Blockade of CCR4 DIminishes hypersensitivity and enhances opioid analgesia - evidence from a mouse model of diabetic neuropathy.

Jun 29, 2020

Chemokine signaling has been implicated in the pathogenesis of diabetic neuropathy; however, the role of chemokine CC motif receptor 4 (CCR4) remains unknown. The goal was to examine the function of C...

Chemogenetic silencing of neurons in the mouse anterior cingulate area modulates neuronal activity and functional connectivity.

Jun 29, 2020

The anterior cingulate area (ACC) is an integral part of the prefrontal cortex in mice and supports cognitive functions, including attentional processes, motion planning and execution as well as remot...

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