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Pain General

Effect of Fully Immersive Virtual Reality Treatment Combined with Exercise in Fibromyalgia Patients: A Randomized Controlled Trial.

Jun 18, 2020

This trial was designed to evaluate the effects of fully immersive virtual reality (IVR) treatment combined with exercise training in fibromyalgia patients. Twenty patients were randomized into exerci...

Non-bladder centric interstitial cystitis/bladder pain syndrome phenotype is significantly associated with co-occurring endometriosis.

Jun 18, 2020

Interstitial cystitis/bladder pain syndrome (IC/BPS) and endometriosis are coexistent diagnoses in 48%-65% of women with chronic pelvic pain (CPP), suggesting that dual screening may be warranted. To ...

Promoting unsupervised walking in women with fibromyalgia: a randomized controlled trial.

Jun 18, 2020

The objective of this study is to test the efficacy of a group motivational plus implementation intentions intervention in promoting adherence to an unsupervised walking program recommended for fibrom...

Going beyond RGD: screening of a cell-adhesion peptide library in 3D cell culture.

Jun 18, 2020

In tissue engineering, cell-adhesion peptides (CAPs) such as the ubiquitous arginine-glycine-aspartic acid (RGD) sequence have allowed the functionalization of synthetic materials to mimic macromolecu...

Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS).

Jun 18, 2020

Anhedonia remains a major clinical issue for which there is few effective interventions. Untreated or poorly controlled anhedonia has been linked to worse disease course and increased suicidal behavio...

Transitioning a Practice to Robotic Total Knee Arthroplasty Is Correlated with Favorable Short-Term Clinical Outcomes-A Single Surgeon Experience.

Jun 18, 2020

 This study sought to evaluate the patient experience and short-term clinical outcomes associated with the hospital stay of patients who underwent robotic arm-assisted total knee arthroplasty (TKA)....

The Use of Nitinol Compression Staple Fixation and Bone Graft for Scaphoid Waist Fractures and Nonunion: A Surgical Technique.

Jun 18, 2020

In the management of scaphoid fractures, nonunion is an important complication that can lead to carpal instability and early-onset arthritis. Various techniques have been described to treat scaphoid n...

"What Should I Do First?" The Effect of Manipulated Goal Conflict on Affect, Motivation, and Helping Behavior in Chronic Pain Couples.

Jun 18, 2020

Although support provision by a partner is an important resource for individuals with chronic pain (ICPs), it poses a challenge for partners because it competes with other important personal goals of ...

Clinician-patient movement synchrony mediates social group effects on interpersonal trust and perceived pain.

Jun 18, 2020

Pain is an unfortunate consequence of many medical procedures, which in some patients becomes chronic and debilitating. Among the factors affecting medical pain, clinician-patient (C-P) similarity and...

The Concerns About Pain (CAP) Scale: A patient reported outcome measure of pain catastrophizing.

Jun 18, 2020

Pain catastrophizing (PC) has been recognized as an important and consistent psychosocial predictor of nearly every key pain-related outcome. The purpose of this study was to develop a new measure of ...

Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A.

Jun 18, 2020

Tumor necrosis factor (TNF) and interleukin (IL)-17A are pleiotropic cytokines implicated in the pathogenesis of several autoimmune diseases including rheumatoid arthritis (RA) and psoriatic arthritis...

Use of in vitro assays to identify antibiotics that are cytotoxic to normal equine chondrocytes and synovial cells.

Jun 18, 2020

Intra-articular (IA) antibiotic usage is prevalent in equine practice. However, recent emergence of antimicrobial resistance prompts re-evaluation of antibiotic selection, particularly when used proph...

Mindfulness-Based Stress Reduction for Migraine

Jun 15, 2020

“Among the limited treatment options for patients with migraine, many of those used as preventatives are not highly effective and can create challenging side effects,” says David A. Seminowicz, Ph...

Comparison of the Stopping Opioids after Surgery (SOS) score to preoperative morphine milligram equivalents (MME) for prediction of opioid prescribing after lumbar spine surgery.

Jun 15, 2020

Reliable estimation of the likelihood for prolonged postoperative opioid use may aid targeted interventions for high-risk patients. Previous studies have recommended differing methodologies for predic...

Towards eHealth to support the health journey of headache patients: a scoping review.

Jun 15, 2020

The aim of this study is to (1) review the digital health tools that have been used in headache studies, and (2) discuss the effectivity and reliability of these tools.Many headache patients travel a ...

Neck associated factors related to migraine in adolescents with painful temporomandibular disorders.

Jun 15, 2020

Migraine is a comorbidity of painful temporomandibular disorders (TMDs). Both migraine and painful TMD have associations with neck pain and head posture. The aim of this study was to clarify the role...

Validation of an algorithm for automated classification of migraine and tension-type headache attacks in an electronic headache diary.

Jun 15, 2020

This study evaluates the accuracy of an automated classification tool of single attacks of the two major primary headache disorders migraine and tension-type headache used in an electronic headache di...

Gene Expression Profiling in Fibromyalgia Indicates an Autoimmune Origin of the Disease and Opens New Avenues for Targeted Therapy.

Jun 15, 2020

Fibromyalgia is a chronic disorder characterized by widespread pain and by several non-pain symptoms. Autoimmunity, small fiber neuropathy and neuroinflammation have been suggested to be involved in t...

Sifting the wheat from the chaff? Evidence for the existence of an asymmetric fibromyalgia phenotype.

Jun 15, 2020

The different phenotypic presentations of fibromyalgia (FM) have been infrequently studied and may have diagnostic and therapeutic implications. The aim of this study was to explore differences betwee...

Red-hot chili receptors: a systematic review of TRPV1 antagonism in animal models of psychiatric disorders and addiction.

Jun 15, 2020

Transient Receptor Potential Vanilloid 1 (TRPV1) channels are non-selective cationic polymodal receptors gated by several different chemical and physical stimuli. TRPV1 receptors are distributed in se...

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