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Sleep Disorders

Validation of the GOAL Questionnaire as an Obstructive Sleep Apnea Screening Instrument in Bariatric Surgery Candidates: a Brazilian Single-Center Study.

Aug 06, 2020

To validate the GOAL questionnaire as obstructive sleep apnea (OSA) screening tool in bariatric surgery (BS) patients and compare it with other existing instruments.Before performing full polysomnogra...

Effects of N -(4-hydroxybenzyl) adenine riboside in stress-induced insomnia in rodents.

Aug 06, 2020

Adenosine exhibits a somnogenic effect; however, there is no adenosinergic hypnotic because of cardiovascular effects. This study investigated whether N6-(4-hydroxybenzyl) adenine riboside (T1-11), ex...

Diagnostic meta-analysis of the Pediatric Sleep Questionnaire, OSA-18, and pulse oximetry in detecting pediatric obstructive sleep apnea syndrome.

Aug 06, 2020

The aim of this meta-analysis was to compare the pooled sensitivity and specificity of the Pediatric Sleep Questionnaire (PSQ), Obstructive Sleep Apnea Questionnaire (OSA-18), and pulse oximetry (PO) ...

Sleep abnormalities across different clinical stages of Bipolar Disorder: A review of EEG studies.

Aug 03, 2020

Sleep disturbances are highly prevalent across all stages of Bipolar Disorder. Despite a wealth of research on the neurophysiological features of sleep in this population, progress in this field has b...

Anxiety and depression in COVID-19 survivors: role of inflammatory and clinical predictors.

Aug 03, 2020

Infection-triggered perturbation of the immune system could induce psychopathology, and psychiatric sequelae were observed after previous coronavirus outbreaks. The spreading of the Severe Acute Respi...

Circulating MicroRNA Profile Associated with Obstructive Sleep Apnea in Alzheimer's Disease.

Jul 30, 2020

The diagnosis of obstructive sleep apnea (OSA) in Alzheimer's disease (AD) by polysomnography (PSG) is challenging due to the required collaboration of the patients. In addition, screening questionnai...

Convergent and divergent functional connectivityalterations of hippocampal subregions between short-term and chronic insomnia disorder.

Jul 30, 2020

Insomnia disorder (ID) is reclassified into short-term and chronic subtypes based on recent etiological advances, however, neural mechanisms underlying the subtypes are rarely examined. In this study,...

Development and initial psychometric evaluation of a radiotherapy-related symptom assessment tool, based on data from patients with brain tumours undergoing proton beam therapy.

Jul 30, 2020

Currently, no available tool easily and effectively measures both the frequency, intensity and distress of symptoms among patients receiving radiotherapy. A core symptom set (fatigue, insomnia, pain, ...

Obstructive sleep apnea in pulmonary fibrosis.

Jul 27, 2020

In previous years, there was limited research related to the role of sleep in interstitial lung diseases (ILDs). Physicians treating ILD patients tended to focus mainly on the daily disabling symptoms...

Hypoglossal Nerve Stimulation in a Rabbit Model of Obstructive Sleep Apnea Reduces Apneas and Improves Oxygenation.

Jul 27, 2020

Based on a prior anesthetized model, we developed an unanesthetized model to evaluate the effects of hypoglossal nerve stimulation (HNS) during sleep. We prepared three rabbits with injections of Hyal...

The importance of specialized sleep investigations in children with a suprasellar tumor.

Jul 23, 2020

Disruption of sleep has great impact on quality of life. In children with a suprasellar tumor and hypothalamic-pituitary dysfunction, the circadian rhythm may be disturbed causing sleep problems. Howe...

A novel cell-free formulation for the treatment of knee osteoarthritis generates better patient-reported health outcomes in more severe cases.

Jul 23, 2020

The bioactive cell-free formulation (BIOF2) for cartilage regeneration has shown a major therapeutic response in severe knee osteoarthritis. However, its effect on patients with mild or moderate stage...

The effectiveness of adjustable oral appliance for older adult patients with obstructive sleep apnea syndrome.

Jul 23, 2020

Oral appliance (OA) treatment for obstructive sleep apnea syndrome (OSAS) has attracted more and more attention due to its low price, comfort, portable and non-invasion. This study aimed to investigat...

Fatal familial insomnia: A new case description with early response to immunotherapy.

Jul 20, 2020

Fatal Familial Insomnia (FFI) is a rare prionopathy with autosomal dominant inheritance. Although it owes its name because insomnia is one of the most frequent and core symptoms, its clinical phenotyp...

The effect of age, gender, income, work, and physical activity on mental health during coronavirus disease (COVID-19) lockdown in Austria.

Jul 20, 2020

The impact of Coronavirus disease (COVID-19) and the governmental restrictions on mental health have been reported for different countries. This study evaluated mental health during COVID-19 lockdown ...

A PERIOD3 variable-number-tandem-repeat polymorphism modulates melatonin treatment response in Delayed Sleep-Wake Phase Disorder.

Jul 20, 2020

We examined whether a polymorphism of the PERIOD3 gene (PER3; rs57875989) modulated the sleep promoting effects of melatonin in Delayed Sleep-Wake Phase Disorder (DSWPD). One hundred and four individu...

Upper Airway Stimulation versus Untreated Comparators in Positive Airway Pressure Treatment Refractory Obstructive Sleep Apnea.

Jul 16, 2020

Understand the impact of insurance coverage on sleep apnea outcomes for patients awaiting upper airway stimulation.Examine the natural history of impact of Upper Airway Stimulation treatment versus in...

Patients with obstructive sleep apnea present with chronic up-regulation of serum HIF-1α protein.

Jul 16, 2020

Obstructive sleep apnea (OSA) is a chronic condition that is characterized by recurrent pauses in breathing during sleep causing intermittent hypoxia. The main factor responsible for oxygen metabolism...

Association between irritability and suicidal ideation in three clinical trials of adults with major depressive disorder.

Jul 16, 2020

Irritability in pediatric samples is associated with higher rates of subsequent suicide-related outcomes. No study, to date, has evaluated the longitudinal association between irritability and suicida...

Automatic positive airway pressure for obstructive sleep apnea in heart failure with reduced ejection fraction.

Jul 13, 2020

Moderate-to-severe obstructive sleep apnea (OSA) is highly prevalent in heart failure patients with reduced left ventricular ejection fraction (HFrEF), and is associated with worsening cardiac functio...

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