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Psychiatry General

Is short-term antidepressant treatment effective and safe in bipolar depression? Results from an observational multicenter study.

Dec 24, 2020

To investigate the short-term effectiveness and the short-term and long-term safety of acute antidepressant (AD) treatment of bipolar depression in a naturalistic setting.Patients with bipolar (n = ...

Modified Drinking Motives Questionnaire-Revised: Psychometric Validation in a Psychiatric Sample of Young Adults with Predominantly Polysubstance Use.

Dec 24, 2020

Measures of motives for alcohol use provide an important avenue for understanding underlying psychological reasons that drive substance use and predict distinct patterns of use. The Modified Drinking ...

An alternative analysis of illicit opioid use during treatment in a randomized trial of extended-release naltrexone versus buprenorphine-naloxone: A per-protocol and completers analysis.

Dec 24, 2020

The distinct pharmacological properties and clinical uses of extended-release naltrexone (XR-NTX) and sublingual buprenorphine-naloxone (BUP-NX) present challenges in analyzing patient outcomes.We con...

Short communication: Systematic review on effectiveness of micro-induction approaches to buprenorphine initiation.

Dec 24, 2020

Micro-induction is a novel buprenorphine induction approach that seeks to avoid withdrawal and minimize precipitated withdrawal, both barriers to standard inductions. We aimed to synthesize evidence o...

Cellular and behavioral basis of cannabinioid and opioid interactions: Implications for opioid dependence and withdrawal.

Dec 24, 2020

The brain's endogenous opioid and endocannabinoid systems are neuromodulatory of synaptic transmission, and play key roles in pain, memory, reward, and addiction. Recent clinical and pre-clinical evid...

N-Acetylcysteine Attenuates the Anxiety-Like Behavior and Spatial Cognition Impairment Induced by Doxorubicin and Cyclophosphamide Combination Treatment in Rats.

Dec 24, 2020

Cancer patients can suffer from psychological and cognitive disorders after chemotherapy, which influence quality of life.Oxidative stress may contribute to the psychological and cognitive disorders i...

The Association between Residential Green Space in Childhood and Development of Attention Deficit Hyperactivity Disorder: A Population-Based Cohort Study.

Dec 24, 2020

Access to green space has been hypothesized to have a beneficial impact on children's mental well-being and cognitive development. The underlying mechanisms of the mental health benefits of green spac...

The value of including families in the treatment of anorexia nervosa.

Dec 24, 2020

The aim of this paper is to consider family and wider carer involvement in the treatment of anorexia nervosa, and how this can be used to add value to services. We discuss widely adopted interventions...

The role of neonatal vitamin D in the association of prenatal depression with toddlers ADHD symptoms: A birth cohort study.

Dec 24, 2020

Vitamin D has been demonstrated a "neuroprotective" effect, but it is unclear whether early-life adequate vitamin D protect adverse neurodevelopment. We aimed to examine the role of neonatal vitamin D...

When symptoms become side effects: Development of the side effect attribution scale (SEAS).

Dec 24, 2020

Symptom misattribution is a central process in the nocebo effect but it is not accurately assessed in current side effect measures. We have developed a new measure, the Side Effect Attribution Scale (...

A 52-Week Prophylactic Randomised Control Trial of Omega-3 Polyunsaturated Fatty Acids in Bipolar Disorder.

Dec 21, 2020

Previous work suggests supplementation with omega-3 polyunsaturated fatty acids (PUFAs) may improve mood symptoms in bipolar disorder (BD) although findings remain unclear. In this study we assess the...

Neuroimaging correlates of emotional response-inhibition discriminate between young depressed adults with and without sub-threshold bipolar symptoms (Emotional Response-inhibition in Young Depressed Adults).

Dec 21, 2020

Many subjects with major depression (MDD) exhibit subthreshold mania symptoms (MDD+). This study investigated, for the first time, using emotional inhibition tasks, whether the neural organization of ...

The impact of pre-pregnancy BMI on maternal depressive and anxiety symptoms during pregnancy and the postpartum period: A systematic review and meta-analysis.

Dec 21, 2020

Studies have reported conflicting results on the association between maternal pre-pregnancy weight and adverse mental health outcomes during pregnancy and the postpartum period. This systematic review...

Prevalence of psychological disorders in the COVID-19 epidemic in China: A real world cross-sectional study.

Dec 21, 2020

This study aimed to explore the prevalence of psychological disorders and associated factors at different stages of the COVID-19 epidemic in China.The mental health status of respondents was assessed ...

Development and validation of analytical method for identification of new psychoactive substances using linear retention indexes and gas chromatography-mass spectrometry.

Dec 21, 2020

New Psychoactive Substances (NPS) are quickly developing to evade legislation, posing unprecedented challenges to public health and law enforcement authorities around the world. The aim of this work w...

Unilateral transcranial photobiomodulation for opioid addiction in a clinical practice: A clinical overview and case series.

Dec 21, 2020

Opioid Use Disorders (OUD) cause great disfunction and pain to individuals, families, and societies. There are few good treatments. This paper presents a novel, easily applied, painless, therapy that ...

Implementing harm reduction in non-urban communities affected by opioids and polysubstance use: A qualitative study exploring challenges and mitigating strategies.

Dec 21, 2020

Harm reduction services, which typically provide overdose education and prevention with distribution of naloxone and other supplies related to safer drug use, help reduce opioid-related overdose and i...

Direct and indirect effects of heatwaves on a coral reef fishery.

Dec 21, 2020

Marine heatwaves are increasing in frequency and intensity, and indirectly impacting coral reef fisheries through bleaching-induced degradation of live coral habitats. Marine heatwaves also affect fis...

Prophylactic antibiotics after endoscopic sinus surgery for chronic rhinosinusitis: a randomized, double-blind, placebo-controlled noninferiority clinical trial.

Dec 21, 2020

Surgeons commonly prescribe prophylactic antibiotics after endoscopic sinus surgery (ESS), yet minimal data exist to support this practice. In this study we aimed to assess the impact of post-ESS anti...

Health coaching: a necessary role for medical students?

Dec 21, 2020

The objective of this study is to discuss the strong rationale for training medical students in health coaching and explain the structure of a planned programme at the University of Cambridge.This is ...

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