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Psychiatry General

Clinical experience of electroconvulsive therapy with anaesthetic and muscle relaxant at the Clínica Universidad de La Sabana: 2009-2017.

Jul 17, 2023

Electroconvulsive therapy is an effective and safe procedure, which is indicated mainly in patients with both unipolar and bipolar depressive episodes, mania and schizophrenia, when they do not respon...

Clinical feasibility of radiofrequency ablation using novel adjustable separable electrodes with a multipurpose needle for treating small hepatocellular carcinomas: a prospective single center study.

Jul 17, 2023

The novel separable clustered electrode system with two adjustable active tips (ICAEs) and a fine multipurpose needle (MPN) for temperature monitoring and adjuvant agent injection was developed and v...

A prospective investigation of impacts of comorbid attention deficit hyperactivity disorder (ADHD) on clinical features and long-term treatment response in adult patients with obsessive-compulsive disorder (OCD).

Jul 17, 2023

A close association between obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD) in children and adolescents has been investigated in previous studies. However, few ...

Adverse effects of 21 antidepressants on sleep during acute-phase treatment in major depressive disorder: A systemic review and dose-effect network meta-analysis.

Jul 10, 2023

Sleep-related adverse effects during acute treatment with antidepressants undermine compliance and impede remission. We aimed to address subtypes of sleep-related adverse effects and depict the relati...

Adverse effects of 21 antidepressants on sleep during acute-phase treatment in major depressive disorder: A systemic review and dose-effect network meta-analysis.

Jul 10, 2023

Sleep-related adverse effects during acute treatment with antidepressants undermine compliance and impede remission. We aimed to address subtypes of sleep-related adverse effects and depict the relati...

Inflammatory subgroups of schizophrenia and their association with brain structure: A semi-supervised machine learning examination of heterogeneity.

Jul 10, 2023

Immune system dysfunction is hypothesised to contribute to structural brain changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed and there is a lack of evidence of in...

Mental health literacy and relational health literacy among college students.

Jul 10, 2023

The aim of the present study was to examine MHL and RHL in a sample of college students in the United States, and to explore linkages among literacies and related constructs. Participants were 169 (...

Non-Psychosis Symptoms of Clozapine Withdrawal: a Systematic Review.

Jul 10, 2023

Clozapine is a potent antipsychotic medication with a complex receptor profile. It is reserved for treatment-resistant schizophrenia. We systematically reviewed studies of non-psychosis symptoms of cl...

Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the design of the WaTCh study.

Jul 10, 2023

Thyroid cancer (TC) patients are understudied but appear to be at risk for poor physical and psychosocial outcomes. Knowledge of the course and determinants of these deteriorated outcomes is lacking. ...

Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment.

Jul 03, 2023

Weight gain is a common harmful side effect of atypical antipsychotics used for schizophrenia treatment. Conversely, treatment with the novel phosphodiesterase-10A (PDE10A) inhibitor MK-8189 in clinic...

The self, neuroscience and psychosis study: Testing a neurophenomenological model of the onset of psychosis.

Jul 03, 2023

Basic self disturbance is a putative core vulnerability marker of schizophrenia spectrum disorders. The primary aims of the Self, Neuroscience and Psychosis (SNAP) study are to: (1) empirically test a...

Borderline personality disorder features and their relationship with trauma and dissociation in a sample of community health service users.

Jul 03, 2023

Previous studies have indicated that borderline personality disorder (BPD) is closely associated with trauma and dissociation. Nevertheless, BPD is a heterogeneous condition, and not all people with B...

Applying the Project ECHO Model to Support Implementation and Sustainment of Cognitive Behavioral Therapy for Psychosis.

Jul 03, 2023

Project Extension for Community Healthcare Outcomes (ECHO) is a teleconsultation model that leverages technology to sustain specialized interventions in underresourced settings. We present the applica...

Relationship between stress and resident non-technical skills during interdisciplinary trauma simulations.

Jul 03, 2023

Non-technical skills, such as communication and situation awareness, are vital for patient care and effective surgical team performance. Previous research has found that residents' perceived stress is...

Relationship between stress and resident non-technical skills during interdisciplinary trauma simulations.

Jul 03, 2023

Non-technical skills, such as communication and situation awareness, are vital for patient care and effective surgical team performance. Previous research has found that residents' perceived stress is...

Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling - a potential therapeutic concept?

Jul 03, 2023

Major depressive disorder (MDD) is defined as a complex mental disorder which is characterized by a pervasive low mood and aversion to activity. Several types of neurotransmitter systems e.g. serotone...

Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling - a potential therapeutic concept?

Jul 03, 2023

Major depressive disorder (MDD) is defined as a complex mental disorder which is characterized by a pervasive low mood and aversion to activity. Several types of neurotransmitter systems e.g. serotone...

Analysis of metabolic syndrome and cognitive functional analysis in schizophrenic patients based on psychological intervention.

Jun 26, 2023

In this paper, we explore the characteristics of cognitive dysfunction in patients with schizophrenia complicated with metabolic syndrome (MS), and to explore the effects of psychological intervention...

Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids.

Jun 26, 2023

De novo mutations and copy number deletions in NRXN1 (2p16.3) pose a significant risk for schizophrenia (SCZ). It is unclear how NRXN1 deletions impact cortical development in a cell type-specific man...

Long-term course of cognitive functioning in bipolar disorder: A ten-year follow-up study.

Jun 26, 2023

Cognitive impairments are common in bipolar disorder (BD), but the long-term course remains understudied. Longitudinal data on cognitive functioning from the start of the first treatment could help cl...

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