Nov 19, 2020

The new ATS/ERS/ESCMID/IDSA guideline answers 22 PICO questions on the treatment of lung diseases caused by complex (MAC), , and . Especially in patients with microscopic detection of acid-fast ba...

Nov 19, 2020

Treatment-resistant depression (TRD) is considered a common clinical condition often associated with relevant suicidal ideation and characterized by a severe functional impairment lifetime. Among the ...

Nov 19, 2020

The Australian Treatment Outcomes Profile (ATOP) is a brief instrument measuring recent substance use, risk profile, and general health and wellbeing among clients attending Alcohol and other Drug (Ao...

Nov 19, 2020

Opiate abuse is prevalent among HIV-infected individuals and may exacerbate HIV-associated age-related neurocognitive disorders. However, the extent to which HIV and opiates converge to accelerate pat...

Nov 19, 2020

 The practice of rooming-in for opioid-dependent infants was introduced as the standard of care at our hospital following a pilot study which demonstrated that such infants had shorter lengths of st...

Nov 19, 2020

Previous observational studies have reported an association between impaired glucose metabolism and Alzheimer's disease. This study aimed to examine the causal association of glycemic traits with Alzh...

Nov 16, 2020

To describe a buprenorphine dispensing bottleneck resulting from a pharmacist-perceived Drug Enforcement Administration "cap" on the amount of buprenorphine that can be ordered or stocked.Expert revie...

Nov 16, 2020

The aim of this study was to assess the differences in patient complications as well as patient and staff satisfaction between a mixed-skill unit and an all-registered nurse (RN) unit.It is recognized...

Nov 16, 2020

Retrospective, observational study.To determine the association of patient socioeconomic disadvantage, insurance type, and other characteristics on presenting symptom severity in patients with isolate...

Nov 16, 2020

Prospective follow-up study.The aim of this study was to assess if depressive symptoms change the outcome of lumbar spine fusion (LSF) surgery at a 5-year follow-up.Previous reports of the influence o...

Nov 16, 2020

Brain functional connectivity (FC) analyses based on magneto/electroencephalography (M/EEG) signals have yet to exploit the intrinsic high-dimensional information. Typically, these analyses are constr...

Nov 16, 2020

Neuroprotection targeting mitochondrial dysfunction has been proposed as a potential therapeutic strategy for Parkinson's disease (PD). Ursodeoxycholic acid (UDCA) has been shown to prevent neuronal d...

Nov 16, 2020

The aberrant accumulation of disease-specific protein aggregates accompanying cognitive decline is a pathological hallmark of age-associated neurological disorders, also termed as proteinopathies, inc...

Nov 16, 2020

We searched Embase, PubMed, and CENTRAL from inception until 22 May 2020 to investigate which antipsychotics and/or mood stabilizers are better for patients with bipolar disorder in the maintenance ph...

Nov 16, 2020

To explore the therapeutic effects of lithium combined with second-generation antipsychotics (SGAs) of quetiapine, clozapine, olanzapine, and risperidone for the treatment of manic episodes in patient...

Nov 16, 2020

Ketamine is a potential rapid-acting treatment for depression. Studies have suggested that the side effects are minimal and temporary, but the psychotic symptom side effects have yet to be fully exami...

Nov 16, 2020

Substance use disorder (SUD) is associated with a high risk of physical and mental illness such as anxiety, depression, personality disorders, eating disorders, and abnormal mood changes. During the p...

Nov 16, 2020

Trauma evaluation in the emergency department (ED) can be a stressful event for children. With the goal of minimizing pain, anxiety, and unneeded interventions in stable patients, we implemented the P...

Nov 16, 2020

Nucleosomes cluster together when chromatin folds in the cell to form heterogeneous groups termed "clutches". These structural units add another level of chromatin regulation, for example during cell ...

Nov 16, 2020

Metformin has been recommended as a first-line antidiabetic drug (ADD) for all patients with type 2 diabetes even in the presence of high cardiovascular (CV) risk by American Diabetes Association. In ...