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Psychiatry General

, , and as Potential Candidate Biomarker Genes for Several Clinical Subphenotypes of Depression and Bipolar Disorder.

Nov 19, 2020

GSK3B, BDNF, NGF, NRG1, HTR2C, and PIP4K2A play important roles in molecular mechanisms of psychiatric disorders. GSK3B occupies a central position in these molecular mechanisms and is also modulated ...

Social media use and internalizing symptoms during early adolescence: The role of co-rumination.

Nov 19, 2020

This study examined the longitudinal associations between social media use, co-rumination (repeatedly discussing personal problems with peers), and internalizing symptoms during early adolescence.Self...

The role of cognitive functions in the diagnosis of bipolar disorder: A machine learning model.

Nov 19, 2020

Considering the clinical heterogeneity of the bipolar disorder, difficulties are encountered in making the correct diagnosis. Although a number of common findings have been found in studies on the neu...

Association between Adherence with an Atypical Antipsychotic and with Other Psychiatric Drugs in Patients with Bipolar Disorder.

Nov 19, 2020

Using U.S. pharmacy and medical claims, medication adherence patterns of patients with serious mental illness suggest that adherence to atypical antipsychotics may be related to adherence to other pre...

The haybiome: Characterising the viable bacterial community profile of four different hays for horses following different pre-feeding regimens.

Nov 19, 2020

Respirable dust in conserved forages can pose problems with equid respiratory health, thus soaking (W) and high temperature steaming (HTS) are employed to reduce the levels in hay. The aim of this stu...

[Nontuberculous Mycobacterial Pulmonary Disease - The New ATS/ERS/ESCMID/IDSA Guideline].

Nov 19, 2020

The new ATS/ERS/ESCMID/IDSA guideline answers 22 PICO questions on the treatment of lung diseases caused by complex (MAC), , and . Especially in patients with microscopic detection of acid-fast ba...

Augmentation with Atypical Antipsychotics for Treatment-Resistant Depression.

Nov 19, 2020

Treatment-resistant depression (TRD) is considered a common clinical condition often associated with relevant suicidal ideation and characterized by a severe functional impairment lifetime. Among the ...

Assessing the concurrent validity, inter-rater reliability and test-retest reliability of the Australian Treatment Outcomes Profile (ATOP) in alcohol and opioid treatment populations.

Nov 19, 2020

The Australian Treatment Outcomes Profile (ATOP) is a brief instrument measuring recent substance use, risk profile, and general health and wellbeing among clients attending Alcohol and other Drug (Ao...

Morphine and HIV-1 Tat interact to cause region-specific hyperphosphorylation of tau in transgenic mice.

Nov 19, 2020

Opiate abuse is prevalent among HIV-infected individuals and may exacerbate HIV-associated age-related neurocognitive disorders. However, the extent to which HIV and opiates converge to accelerate pat...

Rooming-in for Infants at Risk for Neonatal Abstinence Syndrome: Outcomes 5 Years following Its Introduction as the Standard of Care at One Hospital.

Nov 19, 2020

 The practice of rooming-in for opioid-dependent infants was introduced as the standard of care at our hospital following a pilot study which demonstrated that such infants had shorter lengths of st...

Glycemic traits and Alzheimer's disease: a mendelian randomization study.

Nov 19, 2020

Previous observational studies have reported an association between impaired glucose metabolism and Alzheimer's disease. This study aimed to examine the causal association of glycemic traits with Alzh...

DEA Disconnect Leads to Buprenorphine Bottlenecks.

Nov 16, 2020

To describe a buprenorphine dispensing bottleneck resulting from a pharmacist-perceived Drug Enforcement Administration "cap" on the amount of buprenorphine that can be ordered or stocked.Expert revie...

Comparing an All-RN Unit to a Mixed-Skill Unit at a Hospital.

Nov 16, 2020

The aim of this study was to assess the differences in patient complications as well as patient and staff satisfaction between a mixed-skill unit and an all-registered nurse (RN) unit.It is recognized...

Greater Socioeconomic Disadvantage is Associated with Worse Symptom Severity at Initial Presentation in Patients Seeking Care for Lumbar Disc Herniation.

Nov 16, 2020

Retrospective, observational study.To determine the association of patient socioeconomic disadvantage, insurance type, and other characteristics on presenting symptom severity in patients with isolate...

Influence of Depressive Symptoms on the Outcome of Lumbar Spine Fusion - a 5-year Follow-up Study.

Nov 16, 2020

Prospective follow-up study.The aim of this study was to assess if depressive symptoms change the outcome of lumbar spine fusion (LSF) surgery at a 5-year follow-up.Previous reports of the influence o...

High-dimensional brain-wide functional connectivity mapping in magnetoencephalography.

Nov 16, 2020

Brain functional connectivity (FC) analyses based on magneto/electroencephalography (M/EEG) signals have yet to exploit the intrinsic high-dimensional information. Typically, these analyses are constr...

Ursodeoxycholic acid protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis in MPTP/MPP-induced Parkinson's disease.

Nov 16, 2020

Neuroprotection targeting mitochondrial dysfunction has been proposed as a potential therapeutic strategy for Parkinson's disease (PD). Ursodeoxycholic acid (UDCA) has been shown to prevent neuronal d...

Emerging potential of cannabidiol in reversing proteinopathies.

Nov 16, 2020

The aberrant accumulation of disease-specific protein aggregates accompanying cognitive decline is a pathological hallmark of age-associated neurological disorders, also termed as proteinopathies, inc...

Mood stabilizers and/or antipsychotics for bipolar disorder in the maintenance phase: a systematic review and network meta-analysis of randomized controlled trials.

Nov 16, 2020

We searched Embase, PubMed, and CENTRAL from inception until 22 May 2020 to investigate which antipsychotics and/or mood stabilizers are better for patients with bipolar disorder in the maintenance ph...

Effects of Lithium Combined with Second-Generation Antipsychotics for the Treatment of Manic Episodes in Patients with Bipolar Disorder: A Naturalistic Study in China.

Nov 16, 2020

To explore the therapeutic effects of lithium combined with second-generation antipsychotics (SGAs) of quetiapine, clozapine, olanzapine, and risperidone for the treatment of manic episodes in patient...

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