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Psychiatry General

Death and Grieving for Family Caregivers of Loved Ones With Life-Limiting Illnesses in the Era of COVID-19: Considerations for Case Managers.

Nov 16, 2020

Family caregivers of a loved one with a life-limiting or terminal illness are often overwhelmed by, and underprepared for, their responsibilities. They often need help from family members and friends ...

Efficacy and safety of Hominis placenta pharmacopuncture on mild cognitive impairment: Randomized, double blind, placebo-controlled, multi-center trial.

Nov 16, 2020

Mild cognitive impairment (MCI) is cognitive decline which can be observed in a wide range of cognitive domains. It is considered as a prodromal stage of dementia; therefore, strategies for treatment ...

Toxicology Screening Testing in Patients Undergoing Spine Surgery: A Prospective Observational Pilot Study.

Nov 16, 2020

Chronic opioid use and polypharmacy are commonly seen in chronic pain patients presenting for spine procedures. Substance abuse and misuse have also been reported in this patient population. Negative ...

Impact of surgical technique and analgesia on clinical outcomes after lung transplantation: A STROBE-compliant cohort study.

Nov 16, 2020

There is paucity of data on the impact of surgical incision and analgesia on relevant outcomes.A retrospective STROBE-compliant cohort study was performed between July 2007 and August 2017 of patients...

Rapid Administration of Ketamine for Abscess Drainage in Children-A Dose Finding Study.

Nov 16, 2020

To estimate the minimum dose and total sedation time of rapidly infused ketamine that achieves 3 to 5 minutes of effective sedation in children undergoing abscess incision and drainage in the emergenc...

Intrinsic Brain Architecture and Attentional & Mood Symptoms

Nov 16, 2020

With the incidence of mental disorders increasing, it is essential to understand the neurodevelopmental trajectory of psychiatric symptoms. This study aims to evaluate whether the strength of cooling ...

Cortical Connectivity Antidepressant Moderators for Depressive Disorder

Nov 16, 2020

Several magnetic resonance imaging (MRI) findings suggest the role of cortical connectivity treatments in the treatment and selectivity for major depressive disorder (MDD). However, its clinical utili...

Cognitive-Behavioral Treatments for Anxiety in Children with Autism

Nov 16, 2020

Anxiety is a common symptom in young individuals with autism spectrum disorder (ASD). Though psychological therapies for treating anxiety have been proposed, their efficacy has not been established. T...

Association of OPRM1 Functional Coding Variant With Opioid Use Disorder

Nov 16, 2020

With the opioid crisis continually increasing, it is crucial to understand the biological and biochemical mechanisms of opioid abuse. This study aims to identify the genetic risk variants for opioid u...

Adjunctive Psychotherapy for Bipolar Disorder

Nov 16, 2020

Various therapies have been recognized as adjuncts to pharmacotherapy for bipolar disorder patients. However, their efficacy has not been well studied. This study aims to evaluate how using manualized...

Association between Inflammation, Metabolic Dysregulation, and Depression

Nov 16, 2020

Several observational studies have highlighted the associations between C-reactive protein and interleukin, a cytokine-stimulating substance that induces depressive symptoms. However, whether inflamma...

Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template.

Nov 12, 2020

In this work, we studied a series of carfentanyl amide-based opioid derivatives targeting the mu opioid receptor (μOR) and the delta opioid receptor (δOR) heteromer as a credible novel target in pai...

The Relationship between Online Sexual Solicitation and Internet Addiction in Adolescents.

Nov 12, 2020

The purpose of this study is to investigate the association between online sexual solicitation (OSS) and internet accessibility, usage, and addiction in adolescents. The study was conducted with 48 ad...

Loneliness during the first half-year of COVID-19 Lockdowns.

Nov 12, 2020

During the first 6-months of the COVID-19 pandemic, the primary weapons against the spread of the virus have included local government orders for restriction of movement and broad implementation of fa...

(m)RVD-hemopressin (α) and (m)VD-hemopressin (α) improve the memory-impairing effect of scopolamine in novel object and object location recognition tasks in mice.

Nov 12, 2020

Dysfunction of cholinergic system plays an important role in disease associated with cognitive blockage, such as Alzheimer's disease (AD). Central administration of scopolamine, an antagonist of acety...

A compound downregulation of SRRM2 and miR-27a-3p with upregulation of miR-27b-3p in PBMCs of Parkinson's patients is associated with the early stage onset of disease.

Nov 12, 2020

Parkinson's disease (PD) is diagnosed when motor symptoms emerges, which almost 70% of dopamine neurons are lost. Therefore, early diagnosis of PD is crucial to prevent the progress of disease. Blood-...

The effect of concomitant benzodiazepine use on neurocognition in stable, long-term patients with bipolar disorder.

Nov 12, 2020

Neurocognitive dysfunction is a common feature of bipolar disorder even in euthymia, and psychopharmacological treatment could have an effect on cognition. Long-term prescription of benzodiazepines in...

Electroconvulsive Therapy in Mania: A Review of 80 Years of Clinical Experience.

Nov 12, 2020

Resistance to pharmacological agents is commonly encountered in the treatment of acute episodes of mania. In contemporary practice guidelines, electroconvulsive therapy (ECT), once a widely used stand...

Lithium - past, present, future.

Nov 12, 2020

A narrative review of past, present, and future of lithium use in psychiatry.The most important references on the topic were reviewed with special emphasis on the author's works.The history of medical...

Pre-adolescent stress disrupts adult, but not adolescent, safety learning.

Nov 12, 2020

Anxiety disorders are highly prevalent across the lifespan, although diagnoses peak early in adolescence. As a method for inhibiting fear, safety signals have the potential to augment conventional tre...

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