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Psychiatry General

A compound downregulation of SRRM2 and miR-27a-3p with upregulation of miR-27b-3p in PBMCs of Parkinson's patients is associated with the early stage onset of disease.

Nov 12, 2020

Parkinson's disease (PD) is diagnosed when motor symptoms emerges, which almost 70% of dopamine neurons are lost. Therefore, early diagnosis of PD is crucial to prevent the progress of disease. Blood-...

The effect of concomitant benzodiazepine use on neurocognition in stable, long-term patients with bipolar disorder.

Nov 12, 2020

Neurocognitive dysfunction is a common feature of bipolar disorder even in euthymia, and psychopharmacological treatment could have an effect on cognition. Long-term prescription of benzodiazepines in...

Electroconvulsive Therapy in Mania: A Review of 80 Years of Clinical Experience.

Nov 12, 2020

Resistance to pharmacological agents is commonly encountered in the treatment of acute episodes of mania. In contemporary practice guidelines, electroconvulsive therapy (ECT), once a widely used stand...

Lithium - past, present, future.

Nov 12, 2020

A narrative review of past, present, and future of lithium use in psychiatry.The most important references on the topic were reviewed with special emphasis on the author's works.The history of medical...

Pre-adolescent stress disrupts adult, but not adolescent, safety learning.

Nov 12, 2020

Anxiety disorders are highly prevalent across the lifespan, although diagnoses peak early in adolescence. As a method for inhibiting fear, safety signals have the potential to augment conventional tre...

Sexual Health and Interpersonal Relationships Following Chemoradiotherapy For Human Papillomavirus Associated Oropharyngeal Cancer : a cross-sectional study.

Nov 12, 2020

To examine sexual health, including sexual satisfaction, and perceived changes in relationships and sexual relationships of human papillomavirus oropharyngeal cancer (HPV-OPC) survivors ≥12 months f...

Local Targeting of Lung-Tumor-Associated Macrophages with Pulmonary Delivery of a CSF-1R Inhibitor for the Treatment of Breast Cancer Lung Metastases.

Nov 12, 2020

The lungs are major sites of metastases for several cancer types, including breast cancer (BC). Prognosis and quality of life of BC patients that develop pulmonary metastases are negatively impacted. ...

Equine-assisted activities and therapies in children with attention deficit hyperactivity disorder: A systematic review.

Nov 12, 2020

Attention deficit hyperactivity disorder (ADHD) is a disorder characterized by problems of inattention and impulsive hyperactivity. Equine-assisted activities and therapies (EAAT) have become an emerg...

SYSTEMATIC REVIEW: INVESTIGATING THE PROGNOSTIC PERFORMANCE OF FOUR NON-INVASIVE TESTS IN ALCOHOL-RELATED LIVER DISEASE.

Nov 12, 2020

Mortality of Alcohol-related-Liver-Disease (ArLD) is increasing, and liver fibrosis stage is the best mortality predictor. Non-invasive-tests (NIT) are increasingly used to detect fibrosis, but their ...

Perceptions of coordinated movement.

Nov 12, 2020

Humans are highly social creatures who use others' movements to evaluate their social competencies. Smooth movement specifically signals an attractive, trustworthy or competent person. Those with Deve...

Phoneutria nigriventer Tx3-3 peptide toxin reduces fibromyalgia symptoms in mice.

Nov 12, 2020

Fibromyalgia is characterized by the amplification of central nervous system pain with concomitant fatigue, sleep, mood disorders, depression, and anxiety. It needs extensive pharmacological therapy. ...

Prevalence of advanced heart failure and use of palliative care in admitted patients: Findings from the EPICTER study.

Nov 12, 2020

Palliative care in patients with advanced heart failure is strongly recommended by Clinical Practice Guidelines. We aimed to calculate the prevalence of advanced heart failure in admitted patients, to...

Effect of the morphine/heroin vaccine on opioid and non-opioid drug-induced antinociception in mice.

Nov 12, 2020

Pain is a common symptom in patients with opioid use disorder (OUD), which increases synthetic and illicit synthetic opioid abuse and even fatalities due to opioid overdose. Many FDA-approved drugs ar...

Pathological findings in a patient with alpha-synuclein p.A53T and familial Parkinson's disease.

Nov 12, 2020

The present report documents a patient harboring an alpha-synuclein p.A53T variant from a family presenting with autosomal dominant inheritance, including four patients clinically diagnosed with Parki...

Cost-effectiveness of duloxetine for knee OA subjects: The role of pain severity.

Nov 12, 2020

Establish the impact of pain severity on the cost-effectiveness of generic duloxetine for knee osteoarthritis (OA) in the United States.We used a validated computer simulation of knee OA to compare us...

Predictors of Bipolar Disorder Versus Schizophrenia Diagnosis in a Multicenter First Psychotic Episode Cohort: Baseline Characterization and a 12-Month Follow-Up Analysis.

Nov 09, 2020

The aim of this study was to identify predisposing factors and clinical features at baseline that might help predict diagnosis of bipolar disorder vs schizophrenia in a first-episode psychosis (FEP) c...

Preliminary evidence for a relationship between prospective memory and PTSD symptoms in the general population.

Nov 09, 2020

PTSD sufferers often have problems with remembering the past, but do they also have trouble remembering tasks to be completed in the future? We argue characteristics of PTSD-such as negative appraisal...

Post-COVID-19 Epidemic: Allostatic Load among Medical and Nonmedical Workers in China.

Nov 09, 2020

As the fight against the COVID-19 epidemic continues, medical workers may have allostatic load.During the reopening of society, medical and nonmedical workers were compared in terms of allostatic load...

Action mechanism of Roman chamomile in the treatment of anxiety disorder based on network pharmacology.

Nov 09, 2020

Anxiety disorder is a common psychiatric disease. Roman chamomile as medicine or tea has long been used as a mild tranquilizer to reduce anxiety, but the mechanism is unclear. This research is based o...

Adapting implementation science for higher education research: the systematic study of implementing evidence-based practices in college classrooms.

Nov 09, 2020

Finding better ways to implement effective teaching and learning strategies in higher education is urgently needed to help address student outcomes such as retention rates, graduation rates, and learn...

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