Nov 05, 2020

Lithium is widely used in the treatment of bipolar disorder. Here we describe the syndrome of irreversible lithium-effectuated neurotoxicity in a patient within therapeutic doses and levels, which per...

Nov 05, 2020

Seasonal pattern (SP) is a bipolar disorder (BD) specifier that indicates a tendency towards affective relapses during specific moments of the year. SP affects 15-25% of BD patients. In the past, SP w...

Nov 05, 2020

Cariprazine, a dopamine D-preferring D/D receptor partial agonist, is approved for the treatment of adults with schizophrenia (1.5-6 mg/day) and manic/mixed (3-6 mg/day) episodes associated with bip...

Nov 05, 2020

Research examining quality of life (QoL) among people living with epilepsy (PWE) consistently highlights the detrimental impact of stigma, anxiety, and depression, as well as the dynamic and changing ...

Nov 05, 2020

Premature ejaculation is the most prevalent male sexual dysfunction and causes significant individual and relational distress in subjects. This study aimed to investigate the underlying psychopatholog...

Nov 05, 2020

Genetically-selected Marchigian Sardinian alcohol-preferring (msP) rats display comorbid symptoms of increased alcohol preference and elevated anxiety-like behavior. Heightened stress sensitivity in m...

Nov 05, 2020

To describe the geographic and spatiotemporal distribution of needle reports in San Francisco, and examine spatial relationships between needle reports and needle disposal boxes, needle disposal kiosk...

Nov 05, 2020

Young people who use drugs have a rising hepatitis C (HCV) incidence in the United States, but they may face barriers to testing and treatment adoption due to stigma.We conducted a cross-sectional stu...

Nov 05, 2020

Anaphylactic reactions to antigens in the perioperative environment are uncommon, but they have a potential to lead to serious morbidity and/or mortality. The incidence of anaphylactic reactions is 1:...

Nov 05, 2020

Amyloid protein aggregates are pathological hallmarks of neurodegenerative disorders such as Alzheimer's (AD) and Parkinson's (PD) diseases and are believed to be formed well before the onset of neuro...

Nov 05, 2020

Purpose An impoverished production of routinized expressions, namely, formulaic language, has been reported for monolingual speakers with Parkinson's disease (PD). Little is known regarding how formul...

Nov 05, 2020

VPS35 is part of the retromer complex and is responsible for the trafficking and recycling of proteins implicated in autophagy and lysosomal degradation, but also takes part in the degradation of mito...

Nov 05, 2020

In many psychiatric settings, patients with complex cases are the rule rather than the exception. These cases are characterized by multidiagnostic conditions, often complicated with distressed social ...

Nov 05, 2020

To assess usage patterns, perceived usability, and effects of institution-specific guidelines (ISGs) for antimicrobials on clinicians' prescribing behavior and the additional benefits of the mobile ap...

Nov 05, 2020

Etanercept, a tumor necrosis factor inhibitor, is an effective drug for patients with active rheumatoid arthritis (RA). Monocyte chemoattractant protein-1 (MCP-1) and nitrotyrosine (NT) are pro-inflam...

Nov 03, 2020

The study aims to understand autoantibody status in a European multi-center cohort with subjects with unknown aetiology of epilepsy. The study also aims to evaluate the APE2 (Antibody Prevalence in Ep...

Nov 03, 2020

The study aims to diagnose MM2- type cortical and thalamic (MM2C and MM2T) sCJD (sporadic Creutzfeld-Jakob disease) at the initial stage using the new criteria. The researchers took the results of su...

Nov 03, 2020

The study aims at understanding the efficiency and safety of using Nusinersen in subjects with SMA (spinal muscular atrophy). The researchers collected studies on subjects above 18 who were diagnosed...

Nov 03, 2020

“Wisdom is a complex multicomponent human personality trait that confers benefits at the individual and societal levels,” explains Dilip V. Jeste, MD. “Empirical research in wisdom has escalated...

Nov 02, 2020

There is an enhanced need of extra corporeal membrane oxygenation which plays a vital role in providing for risk management in the best possible manner. This is because of the reason that there have b...