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Psychiatry General

Could irritability be the key to unlocking the enigma of mixed states?

Oct 29, 2020

It has recently been argued that a unidimensional approach to mood disorders, focusing predominantly on emotions is too narrow to capture the full spectrum of symptoms of affective disorders, and that...

Depressive and anxiety disorders worsen the prognosis of glioblastoma.

Oct 29, 2020

Glioblastoma multiforme (GBM) is one of the most malignant tumors. Depressive and anxiety disorders may co-exist with GBM. We investigated whether depression and anxiety influenced the outcomes of GBM...

Randomized Controlled Trial of Riluzole Augmentation for Posttraumatic Stress Disorder: Efficacy of a Glutamatergic Modulator for Antidepressant-Resistant Symptoms.

Oct 29, 2020

Current pharmacologic treatments for posttraumatic stress disorder (PTSD) have shown limited efficacy, prompting a call to investigate new classes of medications. The current study investigated the ef...

A Global Survey of Disease Burden in Patients Who Carry a Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy.

Oct 29, 2020

The extent to which work productivity, emotional well-being, social interactions, and family life are impacted in patients who self-identify as having chronic inflammatory demyelinating polyneuropathy...

Overview of the possible role of vitamin C in management of COVID-19.

Oct 29, 2020

The mainstay of management of coronavirus disease 2019 (COVID-19) is mainly supportive as to date there is no effective antiviral treatment, apart from remdesivir which has been approved by Food and D...

Sex Differences in the Longitudinal Course and Outcome of Bipolar Disorder in Youth.

Oct 29, 2020

Despite substantial literature on sex differences in adults with bipolar disorder (BD), little is known about this topic in youth; this study examines sex differences in mood symptomatology and psychi...

Developing a Process for the Analysis of User Journeys and the Prediction of Dropout in Digital Health Interventions: Machine Learning Approach.

Oct 29, 2020

User dropout is a widespread concern in the delivery and evaluation of digital (ie, web and mobile apps) health interventions. Researchers have yet to fully realize the potential of the large amount o...

Does cognitive-behavioural therapy improve sleep outcomes in individuals with traumatic brain injury: a scoping review.

Oct 29, 2020

Insomnia symptoms are common after a traumatic brain injury (TBI). Cognitive-behavioural therapy (CBT) to treat sleep disturbances and insomnia (CBT-I) has been used to improve sleep outcomes. It is u...

Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model.

Oct 29, 2020

Learning valence-based responses to favorable and unfavorable options requires judgments of the relative value of the options, a process necessary for species survival. We found, using engineered mice...

Brain-Enriched Coding and Long Non-coding RNA Genes Are Overrepresented in Recurrent Neurodevelopmental Disorder CNVs.

Oct 29, 2020

Autism spectrum disorder (ASD) is a neurodevelopmental condition with substantial phenotypic and etiological heterogeneity. Although 10%-20% of ASD cases are attributable to copy number variation (CNV...

Disparities in Prescription Opioid Misuse Affecting Sexual Minority Adults Are Attenuated by Depression and Suicidal Ideation.

Oct 29, 2020

Heightened rates of prescription opioid misuse have been observed among sexual minority (SM) compared with heterosexual populations. In addition, depression and suicidal ideation are risk factors for...

Use of tramadol and other analgesics following media attention and risk minimization actions from regulators: a Danish nationwide drug utilization study.

Oct 29, 2020

To describe the use of tramadol and other analgesics in Denmark focusing on the impact of media attention (June and December 2017) and regulatory actions (September 2017 and January 2018) on the use o...

Countermeasures for preventing and treating opioid overdose.

Oct 29, 2020

The only medication available currently to prevent and treat opioid overdose (naloxone) was approved by the Food and Drug Administration (FDA) nearly 50 years ago. Because of its pharmacokinetic and p...

Psychological factors associated with sleep disorders in patients with axial spondyloarthritis or psoriatic arthritis: a multicenter cross-sectional observational study.

Oct 29, 2020

Studies in axial spondyloarthritis (AxSp) have shown that intensity of pain, anxiety, depression, and inflammatory activity are associated with poor sleep quality.To describe mood and sleep disorders ...

Optimal temporal artery biopsy length for the diagnosis of giant cell arteritis

Oct 28, 2020

There have been many studies that have been conducted so far in order to calculate the giant cell arteritis, which has become the major type of large vessel vasculitis. There have been many abrupt ons...

Mavrilimumab for severe COVID-19

Oct 28, 2020

There have been various studies that have been conducted so far in order to measure the number of continuous variables and hence, at the same time make sure that serum C-reactive proteins like ferriti...

Anti-TNF therapy needs to be given trial priority in COVID-19 treatment

Oct 28, 2020

The pandemic of the COVID-19 has affected the lives of millions of people in this world. There has been an increasing danger to be faced by the people in terms of health and wealth. This is because of...

Imperfect storm: is interleukin-33 the Achilles heel of COVID-19?

Oct 28, 2020

There have been many attempts that have been made so far in order to unravel the unique cytokine signature of COVID-19 that might prove to be helpful in providing for the clues to disease the mechanis...

Ayurvedic Ways To Cure PCOS Hair Loss

Oct 28, 2020

Introduction The lives of the people these days is not at all easy. The lifestyle pressures have brought about the worst in people. This has made them suffer from various kinds of illnesses and hence...

Tocilizumab in patients with severe COVID-19: a retrospective cohort study

Oct 27, 2020

There has been almost a year since the outbreak of the novel coronavirus and hence, till now there has not been any therapy or treatment to cure pneumonia which might follow after the person has been ...

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