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Psychiatry General

The Relation between Bigotry, racism, and Mental Health

Oct 09, 2020

The disparities these days are widening to such an extent that it is becoming difficult to realize that what is happening in this world. It is really becoming difficult to realize that the people thes...

The Consequences of a Large Cohort Naturalistic Study

Oct 09, 2020

The age of growing up is very critical. People tend to mend their ways for the worse. Therefore, it is important to observe the human mind in the best possible manner. Therefore, the thing which matte...

The effects of early life stress on motivated behaviors: A role for gonadal hormones.

Oct 08, 2020

Motivated behaviors are controlled by the mesocorticolimbic dopamine (DA) system, consisting of projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) and prefrontal cortex (...

Increased thalamic volume and decreased thalamo-precuneus functional connectivity are associated with smoking relapse.

Oct 08, 2020

The thalamus, with the highest density of nicotinic acetylcholine receptor (nAChR) in the brain, plays a central role in thalamo-cortical circuits that are implicated in nicotine addiction. However, l...

Prevalence And Impact Of Myofascial Pain Syndrome In Relapsing-Remitting Multiple Sclerosis And The Effects Of Local Anesthetic Injections For Short-Term Treatment.

Oct 08, 2020

Previous studies have suggested that patients with multiple sclerosis (MS) who have comorbid musculoskeletal disorders have a lower quality of life. However, there is limited data on the relationship ...

Depression Predicts Cognitive and Functional Decline One Month after Coronary Artery Bypass Graft Surgery (NOAHS Study).

Oct 08, 2020

Prior research on cognitive and functional outcomes after coronary artery bypass graft (CABG) surgery has largely explored these two domains in isolation. In this study, we assess baseline depression ...

Age-specific prevalence and determinants of depression in long-term breast cancer survivors compared to female population controls.

Oct 08, 2020

Depression is more prevalent in breast cancer (BC) survivors than in the general population. However, little is known about depression in long-term survivors. Study objectives were: (1) to compare the...

Different iron deposition patterns in akinetic/rigid-dominant and tremor-dominant Parkinson's disease.

Oct 08, 2020

The loss of dopaminergic cells and excessive iron deposition in some deep brain nuclei are associated with the pathophysiology of PD, and different clinical subtypes may indicate different pathologica...

Could "triple-therapy" considered as a novel-optimal treatment model for acute bipolar depression? A prospective real-world research in China.

Oct 08, 2020

Results of researches of bipolar depression treatment are inconsistent and to our knowledge, no study has previously revealed an optimal treatment model for bipolar depression in the real-world throug...

Cariprazine to Treat Schizophrenia and Bipolar Disorder in Adults.

Oct 08, 2020

Antipsychotics are the standard of care when it comes to the treatment of Schizophrenia, and they are often used in Bipolar as well. Their use can come with adverse effects such as extrapyramidal move...

Is it depression or is it bipolar depression?

Oct 08, 2020

This review is intended to guide primary care providers in differentiating patients with bipolar depression from those with unipolar depression and inform patient management. Up to 64% of clinical enc...

Cumulative Cardiovascular Disease Risk and Triglycerides Differentially Relate to Subdomains of Executive Function in Bipolar Disorder; preliminary findings.

Oct 08, 2020

Cardiovascular disease is disproportionally prevalent in bipolar disorder (BD) and has been linked to cognition in preliminary studies. Herein we evaluate the association between known risk factors fo...

Clinical features related to rapid cycling and one-year euthymia in bipolar disorder patients: A multicenter treatment survey for bipolar disorder in psychiatric clinics (MUSUBI).

Oct 08, 2020

Rapid cycling (RC) presents a risk of greater severity in bipolar disorder (BD), whereas patients with one-year euthymia (OYE) have better prognosis. The purpose of this study was to identify the clin...

The potential role of cocaine and heroin co-use in the opioid epidemic in the United States.

Oct 08, 2020

Opioid/heroin use is an epidemic in the United States (US). Polysubstance use dramatically increases risk of adverse overdose outcomes, versus use of a single substance. Co-use of heroin and cocaine, ...

The association of prefrontal cortex response during a natural reward cue-reactivity paradigm, anhedonia, and demoralization in persons maintained on methadone.

Oct 08, 2020

Persons with opioid use disorder (OUD) often experience anhedonia and demoralization, yet there is relatively little research on the pathophysiology of anhedonia and demoralization in OUD treatment an...

A GLP-2 Analogue Protects SH-SY5Y and Neuro-2a Cells Against Mitochondrial Damage, Autophagy Impairments and Apoptosis in a Parkinson Model.

Oct 08, 2020

Glucagon-like peptide-2 (GLP-2) is a peptide hormone that belongs to the glucagon-derived peptide family. We have previously shown that analogues of the sister hormone Glucagon-like peptide-1 (GLP-1) ...

Emotional dysregulation and uncertainty intolerance as transdiagnostic mediators of anxiety in adults with autism spectrum disorders and intellectual disability.

Oct 08, 2020

There is extensive documentation supporting the comorbidity of anxiety and autistic spectrum disorder (ASD). Transdiagnostic factors such as executive functions, emotion regulation, and uncertainty in...

Add-on effect of clarithromycin to oral steroids as post- operative therapy for chronic rhinosinusitis with nasal polyps: a randomised controlled trial.

Oct 08, 2020

Evidence is lacking regarding the efficacy of macrolides and oral corticosteroids in chronic rhinosinusitis with nasal polyps (CRSwNP) after endoscopic sinus surgery (ESS). Therefore, we examined the ...

New information flows for cancer registries: testing the use of laboratory data in the province of Reggio Emilia, Italy.

Oct 08, 2020

Haematological malignancies often escape the standard information flows of cancer registries because diagnosis is not always based on bone marrow histology but, rather, on other laboratory tests.To qu...

In-Plate Cryopreservation of 2D and 3D Cell Models: Innovative Tools for Biomedical Research and Preclinical Drug Discovery.

Oct 08, 2020

Cell-based assays performed in multiwell plates are utilized in basic and translational research in a variety of cell models. The assembly of these multiwell platforms and their use is often laborator...

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