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Psychiatry General

The effect of individualized education with support on breast cancer patients' anxiety and depression during radiation therapy: A pilot study.

Sep 21, 2020

This study was undertaken to determine the effects of individualized education with support intervention on breast cancer patients' anxiety and depression while undergoing radiation therapy (RT). More...

Acceptance and commitment therapy in adult cancer survivors: a systematic review and conceptual model.

Sep 21, 2020

People with cancer experience significant physical and psychological symptoms, during as well as after primary treatment. Acceptance and Commitment Therapy (ACT), a psychological intervention, reduces...

Efficacy of digital cognitive behavioural therapy for insomnia: a meta-analysis of randomised controlled trials.

Sep 21, 2020

Although cognitive behavioural therapy for insomnia (CBT-I) has been recommended the initial therapy for insomnia, its clinical usage remains limited due to the lack of therapists. Digital CBT-I (dCBT...

Motivations to initiate injectable hydromorphone and diacetylmorphine treatment: A qualitative study of patient experiences in Vancouver, Canada.

Sep 21, 2020

Within the context of the ongoing overdose crisis and limitations of conventional opioid treatments, the scale-up of injectable hydromorphone (HDM) and diacetylmorphine (DAM) as evidenced-based treatm...

Individual and social network correlates of recent treatment for substance use disorders among persons who use drugs in Baltimore, MD (2014 - 2017).

Sep 21, 2020

This analysis examined individual and network correlates of treatment enrollment for substance use disorders (SUDs) in the past 6 months and whether these factors varied by type(s) of drug(s) used and...

Naringenin alleviates 6-hydroxydopamine induced Parkinsonism in SHSY5Y cells and zebrafish model.

Sep 21, 2020

6-Hydroxydopamine (6-OHDA) is a neurotoxin that inhibits the mitochondrial complex I causing mitochondrial impairment, aetiology of Parkinson's. Naringenin is a flavanone predominantly present in citr...

A dual-acting 5-HT receptor inverse agonist/MAO-B inhibitor displays glioprotective and pro-cognitive properties.

Sep 21, 2020

The complex etiology of Alzheimer's disease has initiated a quest for multi-target ligands to address the multifactorial causes of this neurodegenerative disorder. In this context, we designed dual-ac...

Melatonin secretion in patients with Parkinson's disease receiving different-dose levodopa therapy.

Sep 21, 2020

Melatonin is involved in the regulation of sleep and circadian biological rhythmicity; decreased melatonin secretion has been associated with circadian disruptions. Previous studies evaluating melaton...

Reduced fronto-striatal volume in attention-deficit/hyperactivity disorder in two cohorts across the lifespan.

Sep 21, 2020

Attention-Deficit/Hyperactivity Disorder (ADHD) has been associated with altered brain anatomy in neuroimaging studies. However, small and heterogeneous study samples, and the use of region-of-interes...

Explaining short-term memory phenomena with an integrated episodic/semantic framework of long-term memory.

Sep 21, 2020

Current thinking about human memory is dominated by distinctions between episodic and semantic memory and between short-term memory (STM) and long-term memory (LTM). However, many memory phenomena see...

Factors associated with positive mental health in young adults with a neurodevelopmental disorder.

Sep 21, 2020

Positive dimension of mental health has gained less attention in previous research on individuals with neurodevelopmenal disorders. However, knowledge on factors associated with mental well-being is c...

A risk score for postoperative nausea and/or vomiting in women undergoing cesarean delivery with intrathecal morphine.

Sep 21, 2020

Postoperative nausea/vomiting affects up to 80% of parturients undergoing cesarean delivery, but there is a lack of obstetric-specific risk-prediction models. We performed this study to identify posto...

Racial discrimination as a mediator of racial disparities in insomnia disorder.

Sep 17, 2020

Racial and ethnic minorities are more likely to suffer from insomnia that is more severe; however, few studies have examined mechanisms by which racial disparities in severity of insomnia disorder may...

Early life stress increases Line1 within the developing brain in a sex-dependent manner.

Sep 17, 2020

Long-interspersing element 1 (Line1)-a retrotransposon that comprises ∼17% of the human genome and ∼24% of the rat genome -is aberrantly expressed in psychiatric disorders such as schizophrenia, b...

Dual mobility acetabular construct with freedom constrained liner for treatment of recurrent dislocations after total hip arthroplasty: A case report and literature review.

Sep 17, 2020

Recurrent dislocation after total hip arthroplasty (THA) using the dual mobility cup system can present challenges, while dual-mobility THA bearings can improve stability in both primary and revision ...

Gambling in children and adolescents.

Sep 17, 2020

Children are susceptible to problems with gambling because of developmental and cognitive immaturities, as well as a sensitivity to peer pressure and marketing.This review uses recent UK data from the...

Unpacking Associations between Mood Symptoms and Screen Time in Preadolescents: a Network Analysis.

Sep 17, 2020

Mounting evidence highlights the link between screen time and adolescent mood problems. However, there are several shortcomings to the extant literature: (1) this link is underexplored in preadolescen...

[Problematic gambling and criminal responsibility].

Sep 17, 2020

In total, 14% to 30 % of individuals with gambling disorder engage in illegal acts to finance such behavior. This clinical situation could be explained by higher gambling severity, associated substan...

Hypertriglyceridemia-induced brain-derived neurotrophic factor in rat submandibular glands.

Sep 17, 2020

Salivary glands produce brain-derived neurotrophic factor (BDNF), which increases plasma BDNF content. Salivary BDNF influences the hippocampus and enhances anxiety-like behaviors. Dyslipidemia affect...

Associations of history of mental illness with smoking and vaping among university students aged 18-24 years in New Zealand: Results of a 2018 national cross-sectional survey.

Sep 17, 2020

Data on associations of history of mental illness (HMI) with smoking and vaping in New Zealand (NZ) are lacking. This study examines these associations in university students aged 18-24 years.Data ca...

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