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Psychiatry General

The project for objective measures using computational psychiatry technology (PROMPT): Rationale, design, and methodology.

Sep 14, 2020

Depressive and neurocognitive disorders are debilitating conditions that account for the leading causes of years lived with disability worldwide. However, there are no biomarkers that are objective or...

Differential and unique patterns of synaptic miRNA expression in dorsolateral prefrontal cortex of depressed subjects.

Sep 14, 2020

Altered synaptic plasticity is often associated with major depressive disorder (MDD). Disease-associated changes in synaptic functions are tightly correlated with altered microRNA (miRNA) expression. ...

Real-time mobile monitoring of bipolar disorder: a review of evidence and future directions.

Sep 14, 2020

Rapidly accumulating data from mobile assessments are facilitating our ability to track the patterns of emotions, behaviors, biologic rhythms, and their contextual influences in real time. These appro...

Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications.

Sep 14, 2020

Individuals with severe psychiatric disorders have a reduced life expectancy compared to the general population. At the biological level, patients with these disorders present features that suggest th...

Evaluation of a personally-tailored opioid overdose prevention education and naloxone distribution intervention to promote harm reduction and treatment readiness in individuals actively using illicit opioids.

Sep 14, 2020

Opioid overdose prevention education and naloxone distribution (OEND) programs include information on general risk factors, overdose recognition, and naloxone utilization. This study evaluated a perso...

Endogenous theta stimulation during meditation predicts reduced opioid dosing following treatment with mindfulness-oriented recovery enhancement.

Sep 14, 2020

Veterans experience chronic pain at greater rates than the rest of society and are more likely to receive long-term opioid therapy (LTOT), which, at high doses, is theorized to induce maladaptive neur...

Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE mice.

Sep 14, 2020

Atherosclerosis is mainly caused by stress in arterial microenvironments, which results in the formation of stress granules as a consequence of the stress response. As the core protein of stress granu...

Multiple markers contribute to risk of progression from normal to mild cognitive impairment.

Sep 14, 2020

To identify a parsimonious set of markers that optimally predicts subsequent clinical progression from normal to mild cognitive impairment (MCI).250 clinically normal adults (mean age = 73.6 years,...

A validation of a self-administered screening test for Parkinson's disease.

Sep 14, 2020

The detection and diagnosis of Parkinson's disease (PD) is of paramount importance for optimal treatment and for participation in disease-modifying trials. The present study assesses the diagnostic ac...

The influence of performing gesture type on interpersonal musical timing, and the role of visual contact and tempo.

Sep 14, 2020

Bodily gestures play an important role in the communication of expressive intentions between humans. Music ensemble performance, as an outstanding example of nonverbal human communication, offers an e...

Disentangling the effects of attentional difficulties on fears of social evaluation and social anxiety symptoms: Unique interactions with sluggish cognitive tempo.

Sep 14, 2020

Although fears of negative and positive social evaluation are hallmark cognitive features of social anxiety, attentional difficulties may exacerbate the relation between fears of social evaluation and...

Impact of polysubstance use on high-sensitivity cardiac troponin I over time in homeless and unstably housed women.

Sep 14, 2020

The use of controlled substances like cocaine increases the risk of cardiovascular disease (CVD) and myocardial infarction (MI). However, outside of alcohol and tobacco, substance use is not included ...

Exhaled volatile organic compounds analysis in clinical pediatrics: a systematic review.

Sep 14, 2020

Measured exhaled volatile organic compounds (VOCs) in-breath also referred to as exhaled volatilome have been long claimed as a potential source of non-invasive and clinically applicable biomarkers. H...

Celecoxib Significantly Reduces Opioid Use After Shoulder Arthroplasty.

Sep 14, 2020

The opioid crisis has illuminated the risks of opioid use for pain management, with renewed interest in reducing opioid consumption after common orthopedic procedures. Anti-inflammatory medication is ...

Association between Physical Exercise and Mental Health

Sep 11, 2020

Physical exercise is associated with a myriad of health benefits, such as improved cardiovascular health and lower risk of hypertension and diabetes. However, the association of physical exercise with...

Neighborhood Migrant Density and Risk of Non-Affective Psychosis

Sep 11, 2020

Migrant groups in different regions of the world have experienced a higher risk of psychotic disorders, which is a public mental health priority. This study is to examine whether living in high own-re...

Cognitive Behavioural Therapy for Dissociative Seizures

Sep 11, 2020

Dissociative seizures are a type of non-epileptic seizures that are caused by mental or emotional processes rather than by a physical cause. The objective of this study is to evaluate the effectivenes...

Cannabidiol for the Treatment of Cannabis Use Disorder

Sep 11, 2020

Cannabidiol is a phytocannabinoid studied for its potential role in easing symptoms of several health issues, like anxiety, depression, acne, and heart diseases. However, very little is known about th...

Specialized Early Intervention with or without Standard Care for Psychosis

Sep 11, 2020

The introduction of specialized early intervention (SEI) has shown successful outcomes for the treatment of schizophrenia or other psychotic illnesses. This study aims to compare five years of SEI tre...

Work-Related Sexual Harassment and Risk of Suicide and Suicide

Sep 10, 2020

More than 50% of women report workplace harassment. The objective of this study is to evaluate the relationship between exposure to workplace sexual harassment and the incidence of suicide and suicide...

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