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Psychiatry General

Disentangling time series between brain tissues improves fMRI data quality using a time-dependent deep neural network: DeNN: Artificial intelligence for fMRI denoising.

Sep 10, 2020

Functional MRI (fMRI) is a prominent imaging technique to probe brain function, however, a substantial proportion of noise from multiple sources influences the reliability and reproducibility of fMRI ...

Ligand-based pharmacophore modelling and virtual screening for the identification of amyloid-beta diagnostic molecules.

Sep 10, 2020

Currently, only three molecules, flutemetamol, florbetaben and florbetapir, have been approved for clinical use towards the definitive diagnosis of Alzheimer's disease (AD). Despite the clinically app...

Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau.

Sep 10, 2020

The repeated failures of amyloid-targeting therapies have challenged our narrow understanding of Alzheimer's disease (AD) pathogenesis and inspired wide-ranging investigations into the underlying mech...

Nudge interventions to reduce fish sauce consumption in Thailand.

Sep 10, 2020

High sodium consumption is one of the four major risk factors contributing to non-communicable diseases around the world. Thailand has one of the highest rates of sodium consumption, with fish sauce b...

Analysis of Body Composition and Pain Intensity in Women with Chronic Pelvic Pain Secondary to Endometriosis.

Sep 10, 2020

 To determine the average body composition (percentage of body fat), the anthropometric markers, and the intensity of clinical pain in women with a clinical diagnosis of chronic pelvic pain (CPP) se...

Do Neonatal Infections Require a Positive Blood Culture?

Sep 10, 2020

Neonatal sepsis is a major cause of worldwide morbidity and mortality. Blood cultures are considered the gold standard for diagnosis, but results are often delayed for 24 to 48 hours, and sensitivit...

Impact of Preoperative Opioid Use on 2-Year Patient-Reported Outcomes in Knee Surgery Patients.

Sep 10, 2020

The objectives of this study are to assess perioperative opioid use in patients undergoing knee surgery and to examine the relationship between preoperative opioid use and 2-year postoperative patient...

Predictors of PROMIS Physical Function at 2 Years following Knee Surgery.

Sep 10, 2020

The purpose of this study was to evaluate Patient-Reported Outcomes Measurement Information System physical function (PROMIS PF) 2 years following knee surgery, and identify preoperative factors assoc...

Absence of Iodinated Contrast Hypersensitivity and Characterization of Gadolinium Utilization in an Interventional Pain Population.

Sep 10, 2020

Iodinated contrast media (ICM) allergy labels pose a unique clinical problem for the interventional pain physician due to the drawbacks of gadolinium for enhancement during pain procedure, as well as ...

Insomnia Interventions in the Workplace: A Systematic Review and Meta-Analysis.

Sep 07, 2020

The aim of this systematic review and meta-analysis was to identify and evaluate the impact of interventions to improve or reduce insomnia in the workforce through randomized clinical trials. Followin...

New pharmacologic agents for insomnia and hypersomnia.

Sep 07, 2020

Insomnia and hypersomnia are conditions with multifactorial causes that can be difficult to treat. There have been recent developments and changes in the treatment of both conditions, including the ad...

The history of multiple adverse childhood experiences in patients with schizophrenia is associated with more severe symptomatology and suicidal behavior with gender-specific characteristics.

Sep 07, 2020

The current study aims to compare the prevalence of adverse childhood experiences (ACEs) between patients with schizophrenia and non-psychiatric control group, and to analyze the association of having...

Associations between hypomania proneness and attentional bias to happy, but not angry or fearful, faces in emerging adults.

Sep 07, 2020

Mania, the core feature of bipolar disorder, is associated with heightened and positive emotion responding. Yet, little is known about the underlying cognitive processes that may contribute to heighte...

Cannabinoid-Induced Psychosis: A Cross-Sectional Gender Study.

Sep 07, 2020

Gender is a crucial factor in the development of mental illnesses, with an essential influence on clinical characteristics and not only on the prevalence of each disorder. Gender differences in cannab...

Involvement of noradrenergic and serotonergic systems in risk-based decisions between options of equivalent expected value in rats.

Sep 07, 2020

Risk perception is an important factor that may mediate risk-based decision-making processes regulated by noradrenergic (NA) and serotonergic (5-HT) systems. Most risk-based decision-making models inv...

Interpersonal problems in social anxiety disorder across different relational contexts.

Sep 07, 2020

People with social anxiety disorder (SAD) frequently report interpersonal problems across various domains; however, it is unclear whether these problems are observable by others or represent negativel...

Older people's early experience of household isolation and social distancing during COVID-19.

Sep 07, 2020

To explore older people's initial experience of household isolation, social distancing and shielding, and the plans they constructed to support them through the COVID-19 pandemic.Public health guidanc...

School-based e-cigarette education in Alabama: Impact on knowledge of e-cigarettes, perceptions and intent to try.

Sep 07, 2020

Educational programs are needed to combat the sharp rise in adolescent e-cigarette use. We assessed adolescent knowledge about e-cigarettes, perceptions of harmfulness and addictiveness and intent to ...

Association between concurrent antidepressant and hypnotic treatment and the risk of dementia: A nationwide cohort study.

Sep 07, 2020

This study aimed to investigate the risk of dementia among subgroups of patients receiving concurrent antidepressant and hypnotic treatment, antidepressants alone, and hypnotics alone.Multivariate Cox...

The impact of substance use and abuse on opioid demand in lower extremity fracture surgery.

Sep 07, 2020

To describe the perioperative opioid demand in a large population of patients undergoing lower extremity fracture fixation and to evaluate mental disorders such as substance abuse as risk factors for ...

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