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Psychiatry General

Is Methylphenidate Beneficial and Safe in Pharmacological Cognitive Enhancement?

Aug 17, 2020

Nootropics are drugs used to either treat or benefit cognition deficits. Among this class, methylphenidate is a popular agent, which acts through indirect dopaminergic and noradrenergic agonism and, t...

Interprofessional Collaboration and Involvement of Parents in the Management of Painful Procedures in Newborns.

Aug 17, 2020

Newborns are subject to many painful procedures. Pharmacological and non-pharmacological approaches alone are not enough, and it is necessary to consider other contributing elements such as the envir...

Transcriptomic and epigenomic dynamics associated with development of human iPSC-derived GABAergic interneurons.

Aug 17, 2020

GABAergic interneurons (GINs) are a heterogeneous population of inhibitory neurons that collectively contribute to the maintenance of normal neuronal excitability and network activity. Identification ...

A preliminary study on functional activation and connectivity during frustration in youths with bipolar disorder.

Aug 17, 2020

Frustration is associated with impaired attention, heightened arousal, and greater unhappiness in youths with bipolar disorder (BD) vs. healthy volunteers (HV). Little is known about functional activa...

Olfactory markers for depression: Differences between bipolar and unipolar patients.

Aug 17, 2020

The aim of the study was to compare olfactory functions between unipolar and bipolar patients according to the thymic states (depressed, euthymic) and determine specific olfactory variations between t...

The impact of sexual abuse on psychopathology of patients with psychogenic nonepileptic seizures.

Aug 17, 2020

In the present study, we evaluated if the presence of sexual abuse in the clinical history of patients with psychogenic non-epileptic seizures (PNES) is associated with a different psychopathological ...

Emotional reactivity to war stressors: An experience sampling study in people with and without different psychiatric diagnoses.

Aug 17, 2020

There is a lack of knowledge regarding real-time emotional reactivity to high-intensity stressors, particularly in people with mental illness, a potentially vulnerable population. The current study ai...

Eating disorder symptoms and core eating disorder fears decrease during online imaginal exposure therapy for eating disorders.

Aug 17, 2020

Few evidence-based treatments for eating disorders (EDs) exist. Imaginal exposure therapy is a key component of effective treatment for anxiety disorders and post-traumatic stress disorder. However, i...

Natural History of Insomnia Symptoms in the Transition from Childhood to Adolescence: Population Rates, Health Disparities and Risk Factors.

Aug 17, 2020

To determine the sociodemographic, behavioral, and clinical risk factors associated with the persistence, remission, and incidence of insomnia symptoms in the transition from childhood to adolescence....

Physical Exercise and Fitness Level Are Related to Cognitive and Psychosocial Functioning in Adolescents.

Aug 17, 2020

The purpose of this study was to analyze the relationships among physical exercise and fitness with selective attention, concentration, processing speed, general self-efficacy, self-rated health, and ...

Acupuncture for post-stroke insomnia: A protocol for systematic review and meta-analysis.

Aug 17, 2020

Post-stroke insomnia (PSI) is a significant complication of stroke, which often affects patients in various aspects. Acupuncture has fewer side effect and is increasingly used to treat PSI. The purpos...

COVID-19 and Hospital Palliative Care - A service evaluation exploring the symptoms and outcomes of 186 patients and the impact of the pandemic on specialist Hospital Palliative Care.

Aug 17, 2020

Patients hospitalised with COVID-19 have increased morbidity and mortality, which requires extensive involvement of specialist Hospital Palliative Care Teams. Evaluating the response to the surge in d...

Provision of a Drug Deactivation System for Unused Opioid Disposal at Surgical Dismissal: Opportunity to Reduce Community Opioid Supply.

Aug 17, 2020

To determine the impact of a drug deactivation system to post-surgical patients on the rate of opioid prescription disposal.Two hundred post-operative patients discharged after inpatient surgery at a ...

The effect of copy number on α-synuclein's toxicity and its protective role in Bax-induced apoptosis, in yeast.

Aug 17, 2020

Apoptosis is a form of programmed cell death which is essential for the Growth of dividing human cells whereas, in contrast, it is deleterious for post-mitotic cells such as neurons. Bax and α-synucl...

Imaging of dopamine transporters in Parkinson disease: a meta-analysis of F/ I-FP-CIT studies.

Aug 17, 2020

F-FP-CIT and I-FP-CIT are widely used radiotracers in molecular imaging for Parkinson's disease (PD) diagnosis. Compared with I-FP-CIT, F-FP-CIT has superior tracer kinetics. We aimed to conduct a...

Analysis of rare variants of autosomal-dominant genes in a Chinese population with sporadic Parkinson's disease.

Aug 17, 2020

To date, several studies have suggested that genes involved in monogenic forms of Parkinson's disease (PD) contribute to unrelated sporadic cases, but there is limited evidence in the Chinese populati...

Gambling Harm as a Global Public Health Concern: A Mixed Method Investigation of Trends in Wales.

Aug 17, 2020

Recent research evidence has suggested that gambling is a public health concern. A number of studies report the association between gambling activity and increased instances of various other harms, i...

Differences in identification of attention deficit hyperactivity disorder in children between teachers and parents.

Aug 17, 2020

The worldwide prevalence estimates for attention deficit hyperactive disorder (ADHD) are extremely heterogeneous. Diagnosis in children demands symptoms be present in at least 2 different settings, ma...

Silver Adsorption on Calcium Niobate(001) Nanosheets: Calorimetric Energies Explain Sinter-Resistant Support.

Aug 17, 2020

Metal nanoparticles deposited on oxide supports are essential to many technologies, including catalysts, fuel cells and electronics. Therefore, understanding the chemical bonding strength between meta...

Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells.

Aug 17, 2020

Efficient translation of human induced pluripotent stem cells (hiPSCs) depends on implementing scalable cell manufacturing strategies that ensure optimal self-renewal and functional differentiation. C...

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