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Psychiatry General

The Association between Peripheral Inflammation, Brain Glutamate and Antipsychotic Response in Schizophrenia: data from the STRATA collaboration.

May 15, 2023

Glutamate and increased inflammation have been separately implicated in the pathophysiology of schizophrenia and the extent of clinical response to antipsychotic treatment. Despite the mechanistic lin...

Rhynchophylline inhibits methamphetamine dependence via modulating the miR-181a-5p/GABRA1 axis.

May 15, 2023

Uncaria rhynchophylla (Miq.) Miq. ex Havil. is a plant species that is routinely devoted in traditional Chinese medicine to treat central nervous system disorders. Rhynchophylline (Rhy), a predominant...

Effects of the DICE Method to Improve Timely Recognition and Treatment of Neuropsychiatric Symptoms in Early Alzheimer's Disease at the Memory Clinic: The BEAT-IT Study.

May 15, 2023

Neuropsychiatric symptoms (NPS) are highly prevalent in Alzheimer's disease (AD) and are associated with negative outcomes. However, NPS are currently underrecognized at the memory clinic and non-phar...

Olfactory Obsessions: A Study of Prevalence and Phenomenology in the Course of Obsessive-Compulsive Disorder.

May 15, 2023

Olfactory obsessions (OOs) are rarely described in the medical literature. The features of OOs appear consistent with characteristics of a typical obsession, but since they do not involve the realm of...

Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder.

May 15, 2023

The Mood Disorder Questionnaire (MDQ) is a common screening tool for bipolar disorder that assesses manic symptoms. Its utility for genetic studies of mania or bipolar traits has not been fully examin...

Impact of atypical working hours on sleep and mood among healthcare workers.

May 15, 2023

Atypical working hours have raised serious concerns about health effects, such as sleep disorders and psychological repercussions. These schedules are frequent among health professionals having the ob...

Generation and Characterization of the First Murine Model of Alzheimer's Disease with Mutated AβPP Inserted in a BALB/c Background (C.B6/J-APPswe).

May 15, 2023

Numerous mouse models of Alzheimer's disease (AD) are available, but all suffer from certain limitations, thus prompting further attempts. To date, no one model exists with amyloidopathy in a BALB/c s...

Cannabidiol in children with treatment-resistant epilepsy with myoclonic-atonic seizures.

May 15, 2023

This multicenter study aimed to evaluate the efficacy and tolerability of add-on cannabidiol (CBD) in treatment-resistant patients with epilepsy with myoclonic-atonic seizures (EMAtS) (n = 22) and S...

The Relationship Between Cannabis Use and Affect Differs by Social Context

May 12, 2023

The following is a summary of "Association between affect and cannabis use varies by social context," published in the February 2023 issue of Drug and Alcohol Dependence by Denson et al. The gl...

The Evolution of Beliefs and Attitudes Towards Alcohol Consumption Across Generations

May 11, 2023

The following is a summary of "Generational shifts in attitudes and beliefs about alcohol: An age-period-cohort approach," published in the February 2023 issue of Drug and Alcohol Dependence by Living...

Frailty Linked to Suicide Attempt Risk in Elderly US Veterans

May 10, 2023

The following is a summary of "Association of Frailty With Risk of Suicide Attempt in a National Cohort of US Veterans Aged 65 Years or Older," published in the February 2023 issue of Psychiatry by Ku...

Office-based Buprenorphine Treatment for Opioid Use Disorder: Cost-effectiveness

May 09, 2023

The following is a summary of "Cost-effectiveness of office-based buprenorphine treatment for opioid use disorder," published in the February 2023 issue of Drug and Alcohol Dependence by Qian et al. ...

Exploring the Cannabis Use & Sleep Quality: An Electronic Daily Diary Study of Adults

May 08, 2023

The following is a summary of "Cannabis use and sleep quality in daily life: An electronic daily diary study of adults starting cannabis for health concerns," published in the February 2023 issue of D...

Preoperative mechanical bowel preparation for gynecologic surgeries: a systematic review with meta-analysis.

May 08, 2023

To assess the efficacy and safety of mechanical bowel preparation before benign laparoscopic or vaginal gynecologic surgeries.Database searches of MEDLINE (PubMed), EMBASE (OVID), Cochrane Central Reg...

Unrevealing the shared genetic mechanisms underlying C-reactive protein and schizophrenia.

May 08, 2023

Longitudinal observational studies and Mendelian randomization research have obtained contradictory conclusions regarding the association between C-reactive protein (CRP) level and schizophrenia risk....

Gestational Exposure to Haloperidol Changes Cdkn1a and Apaf1 mRNA Expressions in Mouse Hippocampus.

May 08, 2023

The onset of schizophrenia is associated with both genetic and environmental risks during brain development. Environmental factors during pregnancy can represent risk factors for schizophrenia, and we...

Differences in the gut microbiome across typical ageing and in Parkinson's disease.

May 08, 2023

The microbiota-gut-brain axis' role in Parkinson's disease (PD) pathophysiology, and how this differs from typical ageing, is poorly understood. Presently, gut-bacterial diversity, taxonomic abundance...

Effects of Danggui-Shaoyao-San on central neuroendocrine and pharmacokinetics in female ovariectomized rats.

May 08, 2023

The traditional Chinese medicine formula Danggui-Shaoyao-San (DSS) has been reported to have estrogen-like effects and therapeutic effects on the symptoms of Alzheimer's disease (AD).To explore whethe...

Psychotic-like experiences in general population: Psychiatric comorbidity and impact on quality of life across lifespan.

May 08, 2023

In this study, we aimed to determine the prevalence of Psychotics-Like Experiences according to age group and their association with psychiatric disorders through these different age-group, as well as...

Unlocking the potential of snake venom-based molecules against the malaria, Chagas disease, and leishmaniasis triad.

May 08, 2023

Malaria, leishmaniasis and Chagas disease are vector-borne protozoal infections with a disproportionately high impact on the most fragile societies in the world, and despite malaria-focused research g...

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