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Psychiatry General

Acute effects of Adaptive Deep Brain Stimulation in Parkinson's disease.

Aug 03, 2020

Beta-based adaptive Deep Brain Stimulation (aDBS) is effective in Parkinson's disease (PD), when assessed in the immediate post-implantation phase. However, the potential benefits of aDBS in patients ...

Evaluation and optimization of common lipid extraction methods in cerebrospinal fluid samples.

Aug 03, 2020

A typical lipidomics approach aims at the simultaneous analysis of a multitude of lipid species from different lipid classes with highest possible sensitivity for all target lipids. Efficient extracti...

Monoterpene indole alkaloids with acetylcholinesterase inhibitory activity from the leaves of Rauvolfia vomitoria.

Aug 03, 2020

Seventeen monoterpene indole alkaloids, including seven new alkaloids (1-7) and ten known analogues (8-17), were isolated and identified from the leaves of R. vomitoria. The structures of new alkaloid...

Multimorbidity and psychotropic polypharmacy among participants with autism spectrum disorder with intellectual disability.

Aug 03, 2020

Nowadays, adults with autism spectrum disorder (ASD) experience several comorbidities whose treatment implies a wide range of psychotropic prescriptions. This study aimed to evaluate medication-relate...

The Neurodevelopmental Spectrum of Synaptic Vesicle Cycling Disorders.

Aug 03, 2020

In this review, we describe and discuss neurodevelopmental phenotypes arising from rare, high penetrance genomic variants which directly influence synaptic vesicle cycling (SVC disorders). Pathogenic ...

Adjunctive effect of acupressure to pharmacological treatment on depression, anxiety and stress in knee osteoarthritis patients.

Aug 03, 2020

of the study were to check the effectiveness of acupressure therapy with pharmacological treatment on pain, depression, anxiety and stress in knee osteoarthritis patients. To assess the effect of pain...

Using Droplet Digital PCR in the Detection of Mycobacterium tuberculosis DNA in FFPE Samples.

Aug 03, 2020

Droplet digital PCR (ddPCR) is a technology that has higher sensitivity over real-time PCR in the identification of trace DNA. However, the use of ddPCR for the detection of Mycobacterium tuberculosis...

fMRI network correlates of predisposing risk factors for delirium: A cross-sectional study.

Aug 03, 2020

Delirium, the clinical expression of acute encephalopathy, is a common neuropsychiatric syndrome that is related to poor outcomes, such as long-term cognitive impairment. Disturbances of functional br...

Effects of high-intensity interval training compared with resistance training in prostate cancer patients undergoing radiotherapy: a randomized controlled trial.

Jul 30, 2020

Exercise training has shown beneficial effects in the management of radiotherapy-related side effects in prostate cancer (PCa) patients undergoing radiation therapy (RT). However, the optimal modality...

Cost and quality-of-life impacts of community treatment orders (CTOs) for patients with psychosis: economic evaluation of the OCTET trial.

Jul 30, 2020

Current RCT and meta-analyses have not found any effect of community treatment orders (CTOs) on hospital or social outcomes. Assumed positive impacts of CTOs on quality-of-life outcomes and reduced ho...

Maternal Immune Activation Causes Schizophrenia-like Behaviors in the Offspring through Activation of Immune-Inflammatory, Oxidative and Apoptotic Pathways, and Lowered Antioxidant Defenses and Neuroprotection.

Jul 30, 2020

Schizophrenia is a complex neuropsychiatric disorder, influenced by a combined action of genes and environmental factors. The neurodevelopmental origin is one of the most widely recognized etiological...

Stability of admission diagnoses; data from a specialized in-patient treatment facility for dual diagnosis.

Jul 30, 2020

We investigated the stability of diagnoses during admission over an 11-year period in patients admitted to a highly specialized integrated dual diagnosis treatment facility in Denmark using diagnosis ...

Do Meso-Limbic Gene Expression Findings from Mouse Models of Cocaine Self-Administration Recapitulate Human Cocaine Use Disorder?

Jul 30, 2020

Animal models of drug use have been employed for over 100 years to facilitate the identification of mechanisms governing human substance use and addiction. Most cross-species research on drug use/ad...

Mother-to-Infant Bonding in Women with Postpartum Psychosis and Severe Postpartum Depression: A Clinical Cohort Study.

Jul 30, 2020

Mother-to-infant bonding is important for long-term child development. The aim of this study was to investigate bonding in women admitted to a Mother and Baby Unit with postpartum depression (PD, = 6...

Revision of the fear of cancer recurrence cognitive and emotional model by Lee-Jones et al with women with breast cancer.

Jul 30, 2020

Fear of cancer recurrence (FCR) is among the top unmet concerns reported by breast cancer survivors. Despite the sizable literature on FCR, few theoretical models have been empirically tested. One of ...

Convergent and divergent functional connectivityalterations of hippocampal subregions between short-term and chronic insomnia disorder.

Jul 30, 2020

Insomnia disorder (ID) is reclassified into short-term and chronic subtypes based on recent etiological advances, however, neural mechanisms underlying the subtypes are rarely examined. In this study,...

Development and initial psychometric evaluation of a radiotherapy-related symptom assessment tool, based on data from patients with brain tumours undergoing proton beam therapy.

Jul 30, 2020

Currently, no available tool easily and effectively measures both the frequency, intensity and distress of symptoms among patients receiving radiotherapy. A core symptom set (fatigue, insomnia, pain, ...

Lung cancer stigma: A concept with consequences for patients.

Jul 30, 2020

Patients with lung cancer (LC) report lower quality of life (QoL) and higher levels of psychological distress compared with other cancer populations. Lung cancer stigma (LCS) may in part explain these...

Variability in opioid prescribing practices among cardiac surgeons and trainees.

Jul 30, 2020

The opioid epidemic has become a major public health crisis in recent years. Discharge opioid prescription following cardiac surgery has been associated with opioid use disorder; however, ideal practi...

Effect of Intravenous Acetaminophen on Postoperative Hypoxemia After Abdominal Surgery: The FACTOR Randomized Clinical Trial.

Jul 30, 2020

Opioid-induced ventilatory depression and hypoxemia is common, severe, and often unrecognized in postoperative patients. To the extent that nonopioid analgesics reduce opioid consumption, they may dec...

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