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Psychiatry General

Restrictive eating disorders in children and adolescents: a comparison between clinical and psychopathological profiles.

Jul 30, 2020

DSM-5 describe three forms of restrictive and selective eating: Anorexia Nervosa-Restrictive (AN-R), Anorexia Nervosa-Atypical (AN-A), and Avoidant/Restrictive Food Intake Disorder (ARFID). While AN i...

Cardiovascular effects of repeated subanaesthetic ketamine infusion in depression.

Jul 30, 2020

Ketamine produces significant rapid-onset and robust antidepressant effects in patients with major depressive disorder. However, this drug also has transient cardiovascular stimulatory effects, and th...

Person-specific contributions of brain pathologies to progressive parkinsonism in older adults.

Jul 30, 2020

Mixed-brain pathologies are the most common cause of progressive parkinsonism in older adults. We tested the hypothesis that the impact of individual pathologies associated with progressive parkinsoni...

Evidence for the Confluence of Cigarette Smoking, Other Substance Use, and Psychosocial and Mental Health in a Sample of Urban Sexual Minority Young Adults: The P18 Cohort Study.

Jul 30, 2020

Sexual minority men (SMM) and transgender women (TW) are more likely to smoke cigarettes than heterosexual and cisgender peers, which may exacerbate existing disparities in mental and psychosocial hea...

Comparison of modafinil and pitolisant in narcolepsy: a non-inferiority meta-analytical approach.

Jul 27, 2020

To assess the non-inferiority of pitolisant, a new compound for the relief of excessive daytime sleepiness (EDS) and cataplexy in narcolepsy, compared with modafinil.Randomized controlled trials (RCTs...

Sleep and circadian rhythm in response to the COVID-19 pandemic.

Jul 27, 2020

This commentary highlights the critical role of sleep as a public health issue, particularly during a stressful life period such as the COVID-19 pandemic, and provides evidence-based practical guideli...

Clozapine in the Time of COVID-19.

Jul 27, 2020

Clozapine is the most effective antipsychotic for treatment resistant schizophrenia but adverse reactions to clozapine include neutropenia. The current COVID-19 pandemic may raise specific concerns fo...

Oral quetiapine treatment results in time-dependent alterations of recognition memory and brain-derived neurotrophic factor-related signaling molecules in the hippocampus of rats.

Jul 27, 2020

Antipsychotic drugs (APDs) have a variety of important therapeutic applications for neuropsychiatric disorders. However, they are routinely prescribed off-label across all age categories, a controvers...

Uric acid levels in subjects with schizophrenia: A systematic review and meta-analysis.

Jul 27, 2020

The association between schizophrenia (SZ) and uric acid (UA) levels has been suggested for many years, but without solid evidence. Therefore, we conducted a systematic review and meta-analysis of all...

Aspirin (single dose) for perineal pain in the early postpartum period.

Jul 27, 2020

Perineal trauma, due to spontaneous tears, surgical incision (episiotomy), or in association with operative vaginal birth, is common after vaginal birth, and is often associated with postpartum perine...

Distant mood monitoring for depressive and bipolar disorders: a systematic review.

Jul 27, 2020

Broadening our knowledge of the longitudinal course of mood symptoms is cardinal to providing effective long-term treatments. Research indicates that patients with mental illness are willing to engage...

Lurasidone Efficacy in Mixed Depressive States: A Comparison of Standard Rating Scales to the Koukopoulos Mixed Depression Rating Scale.

Jul 27, 2020

A new mood rating scale for mixed states of depression along with manic-like excitatory symptoms, the Koukopoulos Mixed Depression Rating Scale (KMDRS), was assessed in a post hoc analysis of a random...

Recurrence of Mania or Depression Among Adult Bipolar Patients Who Continued Using Lithium: A Single-group Summary Meta-analysis of Randomized Trials.

Jul 27, 2020

The exact recurrence rate of bipolar disorder in patients receiving lithium maintenance phase treatment and the modifiers associated with recurrence are still unknown.We searched Embase, PubMed, and C...

Evaluation of the efficiency of the web-based epilepsy education program (WEEP) for youth with epilepsy and parents: A randomized controlled trial.

Jul 27, 2020

When youth with epilepsy and their parents have insufficient information about the disease, they are known to have more problems with disease management, and they show poor compliance. Providing accur...

[Thoracoscopic Sympathectomy for Palmar and Axillary Hyperhidrosis].

Jul 27, 2020

This video is a step-by-step description of thoracoscopic sympathectomy.Sweating is essential for thermoregulation. Hyperhidrosis is a condition of excess sweating from the eccrine glands and is assoc...

Prevalence of complicated grief and related factors in elderly individuals in Sabzevar City, Iran.

Jul 27, 2020

Although often undiagnosed and untreated, prolonged grief and its conversion to complicated grief (CG) can lead to functional impairment. Given the impact of CG on mortality and quality of life in eld...

Involvement of the endogenous opioid system in the beneficial influence of physical exercise on amphetamine-induced addiction parameters.

Jul 27, 2020

Psychostimulant drugs addiction is a chronic public health problem and individuals remain susceptible to relapses increasing public expenses even after withdrawal and treatment. Our research group has...

Nalfurafine modulates the reinforcing effects of oxycodone in male and female adolescent C57BL/6J mice.

Jul 27, 2020

Addiction to prescription opioid, such as oxycodone, has affected millions of adolescents and young adults. Kappa opioid receptor (KOP-r) agonist can counterbalance the euphoria effects of mu opioid a...

Prenatal Methamphetamine Exposure and Adverse Neonatal Outcomes: A Nationwide Cohort Study.

Jul 27, 2020

There is limited knowledge on the adverse outcomes in newborns after maternal methamphetamine (MA) use during pregnancy.To compare neonatal outcomes in newborns exposed to MA with the newborns of opio...

Lentiviral delivery of human erythropoietin attenuates hippocampal atrophy and improves cognition in the R6/2 mouse model of Huntington's disease.

Jul 27, 2020

Huntington's disease (HD) is an incurable neurodegenerative disorder caused by a trinucleotide (CAG) repeat expansion in the huntingtin gene (HTT). The R6/2 transgenic mouse model of HD expresses exon...

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